Decoding the cell signals between young proteins and their "chaperones"
Of the 25,000 different proteins in the human body, insulin, antibodies, and collagen are among the few that perform their biological jobs by literally folding into 3D shapes......»»
Wireless antennas harness light to decode cellular communication signals
Monitoring electrical signals in biological systems helps scientists understand how cells communicate, which can aid in the diagnosis and treatment of conditions like arrhythmia and Alzheimer's......»»
Discovery of enzyme pathway may lead to lifesaving leishmaniasis treatments
A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts about 1 million people and kills about 30,000 peopl.....»»
New AA-powered AirTag case promises 10-year lifespan
Aluminum AirTag case replaces coin cell with 2 AA Lithium batteries for extended lifespan. On Wednesday, a startup announced TimeCapsule, a new $20 battery case purported to exten.....»»
Genetically encoded biosensors measure living cells" charge in real time
Biological cells have many vital functions in the organism. For example, they produce proteins, carbohydrates and fats. But they are also responsible for detoxifying harmful molecules and transmitting signals and immune defense steps. A so-called red.....»»
Clever trick to cook young stars detected for first time—astronomers highlight magnetic fields as the missing ingredient
The missing ingredient for cooking up stars in the same way you might steam your Christmas pudding has been spotted for the first time by astronomers. Much like a pressure cooker has a weight on top of its lid to keep the pressure in and get your fes.....»»
Molecular tool demonstrates how bad eggs are identified for destruction by reproductive system
The biological factory that produces reproductive cells has a robust quality control system to identify and eliminate eggs with chromosomal abnormalities. For years, cell biologists have sought to uncover the mechanisms behind this system, relying on.....»»
Researchers highlight role "workhorse protein" plays in keeping nervous system running smoothly
A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission breaks down, devastating dise.....»»
Cellular RNA plays key role in antiviral defense, study finds
Scientists have uncovered a new role for a cell's own RNA in fending off attacks by RNA viruses. Some of the cell's RNA molecules, researchers found, help regulate antiviral signaling. These signals are part of the intricate coordination of immune re.....»»
Tech used by WWI flying aces inspires new cellular behavior discovery
Researchers at the University of Massachusetts Amherst have designed a new technology that takes inspiration from WWI fighter aircraft machine gun and propeller synchronization to manipulate cell behavior by precisely modulating the pH of the cell's.....»»
Study reveals how transcription factors navigate DNA architecture to shape cellular identity
A new study led by Prof. Yosef Buganim from the Hebrew University of Jerusalem and Dr. Abdenour Soufi from the University of Edinburgh reveals how transcription factors (TFs)—key proteins that regulate gene activity—navigate DNA and chromatin str.....»»
Molecular gardening: New enzymes discovered for protein modification pruning
Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including cancer and neurodegenerative disorders......»»
New software unlocks secrets of cell signaling, showing realistic simulations
Researchers at University of California San Diego have developed and tested a new software package, called Spatial Modeling Algorithms for Reactions and Transport (SMART), that can realistically simulate cell-signaling networks—the complex systems.....»»
New method maps hundreds of proteins in cell nuclei simultaneously
Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time. The method, called ChIP–DIP (Chromatin ImmunoPrecipitation Done In Parallel), is a versatile tool f.....»»
Old moon, young crust: Violent volcanism may mean the moon is much older than previously thought
After its formation, the moon may have been the scene of such immense volcanic activity that its entire crust melted several times and was completely churned through. At that time, the moon orbited significantly closer to Earth than today. The result.....»»
Azo-menthol: New molecule can regulate ion channels using light
Located in the cell membrane, TRPM8 ion channels are known as receptors that recognize cold and respond to menthol, the cooling agent in peppermint. In addition, these channels influence pain perception and play a key role in numerous diseases. This.....»»
Political branding is not connecting with young voters, study finds
A recent study examining how young people interpret political brands through the context of brand image, has found there is little differentiation, identification and connection between young voters and politicians......»»
Building a backbone: Scientists recreate the body"s "GPS system" in the lab
Scientists at the Francis Crick Institute have generated human stem cell models which, for the first time, contain notochord—a tissue in the developing embryo that acts like a navigation system, directing cells where to build the spine and nervous.....»»
Young exoplanet"s atmosphere unexpectedly differs from its birthplace
Just as some children physically resemble their parents, many scientists have long thought that developing planets should resemble the swirling disk of gas and dust that births them......»»
Talk to him: How a conversation can shape public support for women"s rights
A single conversation with a close family member may not change a young woman's views on policies protecting their rights, but it can strongly influence young men's attitudes......»»
Good relationships and sex education can help teens understand when behavior is abusive or controlling
Nearly half of young people aged between 13 and 17 who have been in a relationship in the past year have experienced violent or controlling behavior, according to a recent survey from charity the Youth Endowment Fund......»»