Cryo-electron microscopy captures structure of a protein pump
Hailey-Hailey disease is a rare, inherited condition characterized by patches of blisters appearing mainly in the skin folds of the arm pits, groin and under the breasts. It is caused by a mutation in the gene that codes for a specific protein involv.....»»
Glycans can regulate their own biosynthesis by modifying enzyme activity
Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of cells and.....»»
Discovery of critical iron-transport protein in malaria parasites could lead to faster-acting medications
Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise......»»
Engineered bacterial protein offers efficient rare earth metal separation
A newly discovered protein naturally houses an unusual binding site that can differentiate between rare earth elements, and researchers at Penn State have made it even better. Rare earth elements are key components used in everything from modern tech.....»»
Largest-Ever Pair of Black Hole Jets Stretches 23 Million Light-Years
Supermassive black holes can expel jets of material so vast and powerful that they may shape the large-scale structure of the cosmos.....»»
A Giant Structure in Space Challenges Our Understanding of The Universe
A Giant Structure in Space Challenges Our Understanding of The Universe.....»»
James Webb Space Telescope Captures Cosmic Fingerprint 5,000 Light-Years Away
James Webb Space Telescope Captures Cosmic Fingerprint 5,000 Light-Years Away.....»»
Novel light source enables better temporal resolution of UV-induced molecular dynamics
The Attosecond Science group at the Center for Free-Electron Laser Science has developed a novel light source capable of producing extremely short pulses for the investigation of UV-induced molecular dynamics with unprecedented temporal resolution. S.....»»
Re-analysis of Milky Way"s central supermassive black hole shows elongated structure
A research team led by Assistant Professor Makoto Miyoshi of the National Astronomical Observatory of Japan (NAOJ) has independently re-analyzed observation data of the supermassive black hole at the center of the Milky Way galaxy obtained and publis.....»»
Super-resolution imaging of living tissues achieved by multi-confocal image scanning microscopy
There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues at the frontier of biological research. Professor Xi Peng's group at Peking University has developed a novel imaging tec.....»»
Synthesis method improves catalytic activity by controlling the surface structure of metal particles
Fine-tuning the reactions that produce hydrogen (H2) for use as a clean fuel is an important endeavor to fight against climate change. Researchers at Tohoku University and the Tokyo University of Science have succeeded in improving the catalytic acti.....»»
New method achieves functional protein delivery into living cells
In cooperation with researchers from the China University of Petroleum, the working group of Dr. Werner Nau, Professor of Chemistry at Constructor University, has demonstrated the effectiveness of a new method of intracellular protein transport......»»
Advancing drug delivery: New framework links lipid nanoparticle structure to immune response
A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines beyond vaccines to other therapeutic applications.....»»
On the way to light-controlled medicine: Researchers elucidate the structure of specific photoreceptors
Researchers in biology and medicine have long dreamed of controlling the activities of cells without, for example, having to use chemicals. After all, in a structure as complex as an entire organism, unwanted side-effects can often arise......»»
When ribosomes go rogue
Unusual variations in the cellular protein factory can skew development, help cancer spread, and more. But ribosome variety may also play biological roles, scientists say. In the.....»»
An elegant switch regulates production of protein variants during cell division
Our cells contain thousands of proteins that have gone largely undetected and unstudied until recent years: these are variants of known proteins, which cells can make when their protein-building machinery interacts differently with the same stretch o.....»»
Newly developed methodology breaks molecular symmetry to back one theory about life"s origin
The vast majority of organic molecules (based on a carbon structure) are not flat, but have a three-dimensional geometry. Various results can be obtained depending on the way the atoms are arranged inside each molecule. In some cases, a molecule and.....»»
Faulty fuel pump triggers Honda recall of over 700,000 vehicles in U.S.
A cracked core component in the fuel pump can lead to fuel leaks, increasing the risk of fire if an ignition source is present nearby......»»
Enhancing recombinant protein expression in lettuce
Recombinant proteins are crucial in pharmaceutical and other industries. A production method uses plants as hosts in transient protein expression systems. Researchers at the University of Tsukuba developed a technique to increase recombinant protein.....»»
X-ray spectroscopy study maps ultrafast charge delocalization in aqueous environments
The movement of electron density is a subject of interest for chemists worldwide, as substances interact through electrons. These processes are ultrafast and traditionally require time-resolved experiments at the attosecond level to study and describ.....»»
Turtle genome provides new clues on the evolution of vertebrates
Scientists from the UAB and Iowa State University have generated the genome assemblies of two hidden-neck turtles. The results, which revealed a new three-dimensional structure of the genome within the phylogenetic group of reptiles, birds and mammal.....»»