CRISPR now possible in cockroaches
Researchers have developed a CRISPR-Cas9 approach to enable gene editing in cockroaches, according to a study published by Cell Press on May 16th in the journal Cell Reports Methods. The simple and efficient technique, named "direct parental" CRISPR.....»»
Virtual laboratory allows scientists to simulate specific decreases in gene activity
Imagine you're looking at millions upon millions of mysterious genetic mutations. With CRISPR gene-editing technology, a select few of these mutations might have therapeutic potential. However, proving it would mean many thousands of hours of lab wor.....»»
CRISPR/Cas9 modifies Euglena to create potential biofuel source
News about biofuels sometimes mentions used cooking oil as a feedstock, but if these substances contain animal fat, they can solidify in colder temperatures. This happens because, chemically, the fatty acids of these and many other saturated fats hav.....»»
Beyond needles: Introducing a new, nature-based approach for delivering cargo into egg cells
A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed at the Marine Biological Laboratory (MBL), resolving a major bottleneck to using the gene-editing tool CRISPR-Cas9 in many research o.....»»
Crispr-Enhanced Viruses Are Being Deployed Against UTIs
With antibiotics losing their effectiveness, one company is turning to gene editing and bacteriophages—viruses that infect bacteria—to combat infections......»»
Breaking boundaries: PAM-less genome editing in soybean
CRISPR-Cas9 has transformed crop genetic improvement, yet its reliance on specific protospacer adjacent motif (PAM), sequences limits editing scope and efficiency. In soybean, a critical source of protein and oil, these limitations hinder the develop.....»»
Researchers achieve first CRISPR-based genome editing in Nile grass rats
A team of researchers at Michigan State University has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats......»»
Consumer-grade insecticide sprays fail to control cockroaches, study shows
A common variety of consumer insecticide sprays is mostly ineffective and of "little to no value" in eliminating cockroach infestations, a study in the Journal of Economic Entomology shows......»»
Harnessing compact RNA-guided endonucleases for enhanced genome editing
The review paper "CRISPR Beyond: Harnessing Compact RNA-Guided Endonucleases for Enhanced Genome Editing," authored by Feizuo Wang from National University of Singapore, presents a comprehensive examination of the advancements in CRISPR-Cas technolog.....»»
Unlocking the potential of rapeseed: CRISPR edits for hybrid efficiency
Hybrid production in rapeseed faces several significant challenges, primarily due to the complexities and limitations of current male sterility systems. Traditional methods often involve intricate management processes and are highly sensitive to envi.....»»
Editing for resilience: CRISPR/Cas9 boosts potato stress resistance
Scientists have made a significant breakthrough in agricultural biotechnology by using CRISPR/Cas9 to edit the potato genome, resulting in plants with increased resistance to both biotic and abiotic stresses. This innovation could lead to a new era o.....»»
Precise genetics: New CRISPR method enables efficient DNA modification
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This targeted cut allows the D.....»»
Unlocking carbon"s potential: CRISPR boosts lignocellulose absorption
Lignocellulosic biomass, such as paper mulberry, holds promise for sustainable material production due to its cost-effectiveness and renewability. However, optimizing lignin composition remains challenging due to its complex structure and varied comp.....»»
Novel protein found to inhibit activity of CRISPR-Cas system
In a study published in Nature on July 3, researchers from the Institute of Biophysics of the Chinese Academy of Sciences and the University of Toronto, Canada, discovered a novel anti-CRISPR protein called AcrIF25, which inhibits the activity of the.....»»
New modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues a.....»»
Research improves multiplex mutagenesis to increase experimental efficiency in plant genome editing
CRISPR/Cas9 remains the most powerful tool to generate mutations in plant genomes. Studying the various combinations of mutations has significantly increased the scale of experimental setups, necessitating more space to grow numerous plants......»»
A pest of our own making: Revealing the true origins of the not-so-German cockroach
German cockroaches thrive in buildings all over the world. They're one of the most common cockroach species, causing trouble for people both here and overseas. But in nature, they're nowhere to be found......»»
How cockroaches spread around the globe to become the pest we know today
They're six-legged, hairy home invaders that just won't die, no matter how hard you try......»»
Mystery CRISPR unlocked: A new ally against antibiotic resistance?
CRISPR-Cas systems have revolutionized biotechnology by offering ways to edit genes like a pair of programmable scissors. In nature, bacteria use these systems to fight off deadly viruses. A recent international collaboration led by the University of.....»»
Team develops efficient host-vector system for a model archaeon by solving CRISPR-based host-plasmid conflict
A research group has constructed versatile genetic tools for Saccharolobus islandicus REY15A, one of the very few archaeal models for archaea biology and CRISPR biology research......»»
Microbiome studies help explore treatments for genetic disorders
A collaboration has led to the identification, in a bacterium of the intestine, of new CRISPR-Cas9 molecules that could have a clinical potential to treat genetic diseases such as retinitis pigmentosa, through sub-retinal injections. Anna Cereseto an.....»»