Converting P450 peroxygenase into peroxidase via mechanism-guided protein engineering
Enzyme catalysis is a promising green solution for producing pharmaceuticals, fine chemicals, and biofuels. However, exploring their catalytic promiscuity to expand and enhance the capabilities of enzymes remains challenging......»»
Bioengineers develop protein assembly road map for nature-derived nanobubbles
As far as water gear goes, floaties are not exactly high tech. But the tiny air-filled bubbles some microorganisms use as flotation devices when they compete for light on the water surface are a different story......»»
Drosophila study discovers mechanism that could control longevity, cancer cell production
Researchers at UC Merced have used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging......»»
Breaking boundaries: PAM-less genome editing in soybean
CRISPR-Cas9 has transformed crop genetic improvement, yet its reliance on specific protospacer adjacent motif (PAM), sequences limits editing scope and efficiency. In soybean, a critical source of protein and oil, these limitations hinder the develop.....»»
3D bioprinting materials offer possibility for better bone and soft tissue repair
3D bioprinting is an advanced tissue engineering technique that builds complex tissues using bioactive substances like living cells and scaffolds. It provides personalized tissue repair solutions, reducing immune rejection by using patient-specific c.....»»
Cells use alternative splicing to regulate gene expression, research suggests
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»
How to convert PDF to PowerPoint
Converting a PDF to Powerpoint is quick and straightforward if you use the right tools. Here's how to do it......»»
Investigation reveals global fisheries are in far worse shape than we thought—and many have already collapsed
When fish are taken from our oceans faster than they can reproduce, their population numbers decline. This over-fishing upsets marine ecosystems. It's also bad for human populations that rely on fish for protein in their diets......»»
Study finds RNA molecule controls butterfly wing coloration
A team of international researchers has uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. In a study published in the Proceedings of the National Academy of Sciences, the team, led by Luca L.....»»
Researchers identify genes for low glycemic index and high protein in rice
A team of researchers at the International Rice Research Institute (IRRI) has identified genes and markers responsible for low glycemic index (GI) and high protein content in rice, using genetics and artificial intelligence classification methods......»»
Light-activated polymerization methods unlock new possibilities for intracellular applications
Synthetic polymers play a crucial role in cell biology, serving as delivery vehicles for DNA and drugs, acting as fluorescent probes for cellular sensing, functioning as bioinks for tissue engineering, and mimicking biological functionality (e.g., ar.....»»
Novel encoding mechanism unveiled for particle physics
In the development of particle physics, researchers have introduced an innovative particle encoding mechanism that promises to improve how information in particle physics is digitally registered and analyzed. This new method, focusing on the quantum.....»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
New moves for self defense—how plants can inspire future soft robotic design
For plants, cleaning the air, providing food and medicines, and preserving our ecosystem is just another day's work. In the Department of Mechanical Engineering at Carnegie Mellon University, however, plants are being studied in new ways to inspire f.....»»
Big-name publishers are refusing to let Apple Intelligence train on data
Website owners have a simple mechanism to tell Apple Intelligence not to scrape the site for training purposes, and reportedly major platforms like Facebook and the New York Times are using it.Future expansions to Apple Intelligence may involve more.....»»
Shedding light on the mechanism of yeast DNA repair
DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as blocked DNA replication, can generate double-strand brea.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Bacterial defense strategy has potential application in genome editing
Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method......»»
Study shows an electrically-activated protein regulates spermatogenesis
Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»