Cellular environments shape molecular architecture
Context matters. It's true for many facets of life, including the tiny molecular machines that perform vital functions inside our cells......»»
Ultra-sensitive photothermal microscopy technique detects single nanoparticles as small as 5 nm
The detection of individual particles and molecules has opened new horizons in analytical chemistry, cellular imaging, nanomaterials, and biomedical diagnostics. Traditional single-molecule detection methods rely heavily on fluorescence techniques, w.....»»
Researchers synthesize molecular aggregates for solar energy applications
No molecule stands alone—they need others, at least when it comes to being able to display useful photophysical, electronic, and chemical properties. When individual molecules combine into an aggregate, or a complex of two or more molecules, they b.....»»
Vulnerability prioritization is only the beginning
To date, most technology solutions focused on vulnerability management have focused on the prioritization of risks. That usually took the shape of some risk-ranking structure displayed in a table with links out to the CVEs and other advisory or threa.....»»
The secret to sleepy cells" control of inflammatory secretions
Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells. This drowsy condition is known to provide heal.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
Physicists observe key minuscule molecular interactions in ultra-fast atomic processes
An international team of scientists is the first to report incredibly small time delays in a molecule's electron activity when the particles are exposed to X-rays......»»
Cryo-ET study elucidates protein folding helpers in their natural environment
Cryo-electron tomography (cryo-ET), can be used to visualize and analyze cellular structures in their natural environment. Researchers at the MPI of Biochemistry in Martinsried and the University Medical Center Göttingen have now used cryo-ET to stu.....»»
How a former BMW exec"s advice helped shape a driver-assist specialist"s focus
Provizio CEO Barry Lunn was told early on that cost was king in the automotive sector, which inspired him to try to make advanced driver-assistance systems affordable for every vehicle......»»
What the unique shape of the human heart tells us about our evolution
Mammals, from the mighty blue whale to the tiny shrew, inhabit nearly every corner of our planet. Their remarkable adaptability to different environments has long fascinated scientists, with each species developing unique traits to survive and thrive.....»»
Twisted molecular wires exhibit high single-molecule conductance
From the high-voltage wires that carry electricity over long distances, to the tungsten filaments in our incandescent lights, we may have become accustomed to thinking that electrical conductors are always made of metal. But for decades, scientists h.....»»
Newly discovered, free-living eukaryote is the first known to have lost its mitochondria
An international team of geneticists and molecular biologists has discovered the first-known, free-living eukaryote to have lost its mitochondria. In their study, published in Nature Communications, the group found the eukaryote while investigating t.....»»
Proteins for skin strength also control cell signaling, study suggests
An extensive family of proteins that gives human skin mechanical strength also appears to organize molecular signals that control skin cell activity, a study led by UT Southwestern Medical Center researchers shows. The team's findings, published in D.....»»
Cellular DNA damage response pathways might be useful against some disease-causing viruses
New research reveals that triggering a cell's DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral treatments exist, possibly including human papilloma vir.....»»
How a former BMW exec"s advice helped shape an ADAS specialist"s focus
Provizio CEO Barry Lunn was told early on that cost was king in the automotive sector, which inspired him to try to make advanced driver assistance systems affordable for every vehicle......»»
Researchers teach artificial intelligence about frustration in protein folding
Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict.....»»
We know parents shape children"s reading—but so can aunts, uncles and grandparents, by sharing beloved books
More than 80% of Australians with children encourage them to read. Children whose parents enjoy reading are 20% more likely to enjoy it too......»»
"Masters of shape-shifting": How darkling beetles conquered the world
Large-scale genomic analysis of darkling beetles, a hyper-diverse insect group of more than 30,000 species worldwide, rolls back the curtain on a 150-million-year evolutionary tale of one of Earth's most ecologically important yet inconspicuous creat.....»»
Unveiling the intricate and subtle dance of proteins: Understanding how parasites disarm host defenses
Pathogens hijack host cell functions by expressing or secreting effector proteins, creating environments conducive to their survival and reproduction. These pathogenic microorganisms—including eukaryotic parasites, prokaryotic bacteria, and viruses.....»»
Sea anemone study identifies potentially regenerative stem cells linked to conserved genes
The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the se.....»»
Authentik: Open-source identity provider
Authentik is an open-source identity provider designed for maximum flexibility and adaptability. It easily integrates into existing environments and supports new protocols. It’s a comprehensive solution for implementing features like sign-up, a.....»»