Broad-spectrum inhibition of inflammasome activation by inorganic nanomaterials
Excessive activation of inflammasomes is associated with various diseases, including gout, Alzheimer's disease, atherosclerosis, and type 2 diabetes. Given the pivotal role of macrophages in both inflammasome activation and nanoparticle phagocytosis,.....»»
High-resolution images of the sun show how flares impact the solar atmosphere
Solar flares are a fascinating thing and have a profound effect on what astronomers refer to as "space weather." These events vary with the sun's 11-year solar cycle, releasing immense amounts of radiation across the electromagnetic spectrum (from ex.....»»
Study shows artificial light at night changes the behavior of fish, even into the next generation
Scientists have shown that light pollution—especially light in the blue spectrum—can alter the behavior of fish after only a few nights, and have knock-on effects for their offspring. The team from China has studied how female zebrafish responded.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
Team discovers naturally occurring DNA-protein hybrids
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»
GM-Hyundai tie-up has broad potential
GM and Hyundai provided little detail when they announced a partnership to explore areas in which they can work together, and such collaborations can take years to produce results......»»
Apple is well on its way to making iPhones theft-proof
Apple’s latest theft-prevention measure went live for beta testers yesterday: Activation Lock for iPhone components. The move is likely to generate some controversy, as it introduces another barrier to DIY repairs using parts harvested from brok.....»»
Apple brings Activation Lock to iPhone parts with iOS 18
Earlier this year, Apple announced some changes to its repair policies. Overall, the company has made it easier for users to repair their iPhone with genuine used parts. However, at the same time, Apple also announced that it would bring Activation L.....»»
Surprising hormone-related gene activity discovered in the early larval stage of the Malabar grouper
Researchers at the Okinawa Institute of Science and Technology (OIST)'s Marine Climate Change Unit and Marine Eco-Evo-Devo Unit have highlighted patterns of gene activation during Malabar grouper larval development, revealing an unusual early peak of.....»»
Ketch helps media brands enable privacy-safe data activation
Ketch launched its product suite for digital media brands. The digital media industry faces increasing challenges. Intense FTC scrutiny on targeted advertising, growing pressure to deliver precise, permissioned targeting, and the existential threat o.....»»
The case for adding iron to the ocean for carbon dioxide removal
While the urgent reduction of carbon dioxide (CO2) and other greenhouse gas emissions is needed as the primary activity to curb climate change, there is broad agreement for the need to remove CO2 already in the atmosphere. Given its outsized role in.....»»
Q&A: How single-cell and spatial proteomics reveal proteins" nuanced roles in health and disease
When Steve Carr, senior director of the Proteomics Platform at the Broad Institute of MIT and Harvard, began working in proteomics, the field was able to detect only the most abundant proteins in a given sample. In recent years, increasingly sensitiv.....»»
Novel glass-forming liquid electrolyte shows glass transition across broad range
As the world shifts towards a more sustainable future, the development of advanced electrochemical devices, such as rechargeable batteries with higher energy densities and efficient electrodeposition capabilities, has become increasingly crucial. In.....»»
How vegetation could impact the climate of exoplanets
The term "habitable zone" is a broad definition that serves a purpose in our age of exoplanet discovery. But the more we learn about exoplanets, the more we need a more nuanced definition of habitable......»»
New knowledge about cell receptors paves the way for future drugs against intestinal tumors
A new study from Karolinska Institutet published in Nature Communications provides valuable insights into the activation of receptors on the cell surface. The knowledge could lead to new targeted therapies and drugs against intestinal tumors, among o.....»»
Addigy launches Apple Intelligence device management controls
Apple device management vendor Addigy has announced the immediate availability of new Apple Intelligence controls. These controls, now live within Addigy’s platform, allow IT administrators and Managed Service Providers to test the activation and d.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Ultra-sensitive photothermal microscopy technique detects single nanoparticles as small as 5 nm
The detection of individual particles and molecules has opened new horizons in analytical chemistry, cellular imaging, nanomaterials, and biomedical diagnostics. Traditional single-molecule detection methods rely heavily on fluorescence techniques, w.....»»
Peloton announces $95 “used equipment activation fee”
"Completely ridiculous." Enlarge (credit: Peloton) Peloton will start charging people a one-time $95 "used equipment activation fee" for used bikes purchased from outside of Peloton and its official distribution partner.....»»
A maximally entangled quantum state with a fixed spectrum does not exist in the presence of noise, mathematician claims
For more than 20 years, quantum researchers have wondered whether a quantum system can have maximum entanglement in the presence of noise. A mathematician from Spain recently answered the question: No......»»
Heterogeneous occurrence of evergreen broad-leaved forests revealed by plant fossils in East Asia
Evergreen broad-leaved forests (EBLFs) are the most characteristic biomes in East Asia. They assume a fundamental role in the biodiversity function and ecosystem services of the East Asiatic floristic kingdom. Hence, understanding the historical dyna.....»»