Atomic structure of antifungal drug confirms unusual mechanism, opens door to less-toxic derivatives
Advanced molecular imaging technology has now mapped the structure of a drug widely used to treat fungal infections but whose workings have mystified researchers and physicians for nearly 70 years......»»
Researchers reveal key mechanism in regulating DNA recombination
Meiotic recombination generates genetic diversity and promotes proper chromosomal segregation of parental chromosomes. This process requires a set of recombinases polymerized on single-stranded (ss) DNAs called the nucleoprotein filament to undergo h.....»»
Scientists offer a detailed look at the skeleton of an ancient predator that thrived in extreme conditions
Imagine a world on the brink of collapse: volcanic eruptions spewing toxic gases, oceans turning acidic, and up to 90% of Earth's species vanishing in the blink of an eye. This was the reality at the end of the Permian Period, around 252 million year.....»»
Quantum researchers come up with a recipe that could accelerate drug development
University of Copenhagen mathematicians have developed a recipe for upgrading quantum computers to simulate complex quantum systems, such as molecules. Their discovery brings us closer to being able to predict how new drugs will behave within our bod.....»»
Scientists find plant-like behavior in human cells
A team of scientists from Monash University has solved the structure of a protein known as "LYCHOS," which can detect and regulate cell growth by sensing cholesterol levels in the body......»»
Ancient protein structure may have enabled early molecular evolution and diversification
In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab experiments that have revealed a previously unknown protein fold, which is completely absent in modern proteins......»»
Filament structure found to activate and regulate CRISPR-Cas "protein scissors"
CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, al.....»»
Scientists inject bacteria into fungi to study endosymbiosis
Endosymbiosis is a fascinating biological phenomenon in which an organism lives inside another. Such an unusual relationship is often beneficial for both parties. Even in our bodies, we find remnants of such cohabitation: mitochondria evolved from an.....»»
Webb telescope detects unusual gas jets from Centaur 29P
Inspired by the half-human, half-horse creatures that are part of Ancient Greek mythology, the field of astronomy has its own kind of centaurs: distant objects orbiting the sun between Jupiter and Neptune. NASA's James Webb Space Telescope has mapped.....»»
Beyond "one pore at a time": New method of generating multiple, tunable nanopores
Nanoporous membranes with atomic-scale holes smaller than one-billionth of a meter have powerful potential for decontaminating polluted water, pulling valuable metal ions from the water, or for osmotic power generators......»»
Ring Protect rebrands to Ring Home and adds 24/7 recording
Ring Protect is now Ring Home, and while its pricing structure is the same, it benefits from several cool new features -- including 24/7 recording......»»
Toxic chemicals from Ohio train derailment lingered in buildings for months
New study offers lessons on how to better protect communities from disasters. On February 3, 2023, a train carrying chemicals jumped the tracks in East Palestine, Ohio, rupturing.....»»
Planning a drug"s route in the body with synthetic chemistry
Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins......»»
Toxic chemicals from Ohio train derailment lingered in buildings for months
New study offers lessons on how to better protect communities from disasters. Enlarge / This video screenshot released by the US National Transportation Safety Board (NTSB) shows the site of a derailed freight train in East Pale.....»»
Southern California study finds high levels of airborne plasticizers
A new study documents how Southern Californians are chronically being exposed to toxic airborne chemicals called plasticizers, including one that's been banned from children's items and beauty products......»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
Judge rebuffs citizen lawsuit against Gotion plant but leaves door open
Despite a complaint that “reads like a novel or a thesis,” the Illinois judge couldn't rule out the possibility that claims against the controversial Chinese-owned battery factory in Manteno could be proved......»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
Verizon confirms widespread outage affecting users across the US [Updated]
Update 5:38 p.m. ET: Verizon is slowly fixing the ongoing outage. In a new statement, the company says: “Verizon engineers are making progress on our network issue and service has started to be restored. We know how much people rely on Verizon and.....»»
In storms like Hurricane Helene, flooded industrial sites and toxic chemical releases are a silent and growing threat
Hundreds of industrial facilities with toxic pollutants were in Hurricane Helene's path as the powerful storm flooded communities across the Southeast in late September 2024......»»
Study elucidates a mechanism for phosphorus cycling in subtropical forests
Phosphorus (P) is an important nutrient element in plant photosynthesis. However, the adsorption of mineral P via leaching and erosion leads to a decrease in P availability and consequently P deficiency......»»