Antibodies and SARS-CoV-2 infections: Tthe more the better
Oxford University Hospital tracked infections in 12,500 of its healthcare workers. Enlarge / Oxford University is associated with the hospital that ran this study, as well as a vaccine that is currently undergoing clinical trials. (credit: Gallo.....»»
Researchers develop platform to screen for new class of coronavirus antiviral compounds
Researchers investigating ways to develop a novel class of antiviral drugs to treat coronaviruses, including SARS-CoV-2, which causes COVID-19, have developed a platform that can rapidly screen thousands of compounds to identify potential candidates......»»
Transistor-based sensors offer hope for rapid diagnosis and treatment for COVID-19 and other infections
A solid-state metal oxide transistor-based technology can detect tiny quantities of biomolecules, such as DNA and COVID-19 spike protein, in less than two minutes......»»
Beamlines cast light on SARS-CoV-2, emerging variants and vaccines that will stop them
Ultrabright light from the Advanced Photon Source continues to illuminate mysteries around coronaviruses and shape the vaccines and therapeutics protecting us against variants of concern......»»
An enemy within: Pathogens hide in tissue
Antibiotics cure many bacterial infections. However, some patients suffer a relapse. A research group at the University of Basel has now discovered why some bacteria can survive antibiotic therapy. The team uncovered where the bacteria hide in the bo.....»»
Atomic structure of antifungal drug confirms unusual mechanism, opens door to less-toxic derivatives
Advanced molecular imaging technology has now mapped the structure of a drug widely used to treat fungal infections but whose workings have mystified researchers and physicians for nearly 70 years. Researchers now described in atomistic detail the st.....»»
A longer-lasting COVID vaccine? New study points the way
Researchers have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses. The findings suggest that a component of this protein, called viral polymerase, could potent.....»»
Neutralizing antibodies for emerging viruses
Researchers at Sandia have created a platform for discovering, designing and engineering novel antibody countermeasures for emerging viruses. This new process of screening for nanobodies that "neutralize" or disable the virus represents a faster, mor.....»»
Scientists Discover How the SARS-CoV-2 Virus Evades Our Immune System
Long-time Slashdot reader fahrbot-bot quotes SciTechDaily: A discovery by researchers at the Texas A&M College of Medicine could lead to new therapies to prevent the virus from proliferating in the human body... The underlying mechanism of how SARS-C.....»»
Japanese Scientists Develop Glowing Masks To Detect Coronavirus
A team of scientists at a university in western Japan has developed masks that glow when exposed to ultraviolet light if they contain traces of the coronavirus, using antibodies extracted from ostrich eggs. From a report: The team at Kyoto Prefectura.....»»
Atomic structure of antifungal drug confirms unusual mechanism, opens door to less-toxic derivatives
Advanced molecular imaging technology has now mapped the structure of a drug widely used to treat fungal infections but whose workings have mystified researchers and physicians for nearly 70 years......»»
How the body uses fat to fight infection
New research reveals how our immune cells use the body's fat stores to fight infection. The research could help develop new approaches to treating people with bacterial infections. And the team say their work could one day help treat infections in vu.....»»
SARS-CoV-2 infects sustentacular cells in the olfactory epithelium of COVID-19 patients, study finds
The coronavirus does not appear to infect nerve cells in the olfactory epithelium and in the olfactory bulb, according to new research......»»
How SARS-CoV-2 evades our immune system
Scientists have identified a key mechanism used by the SARS-CoV-2 virus to evade host immune systems......»»
Miniature llama antibodies could help fight SARS-CoV-2 variants
Llamas make antibodies that are much smaller than their human counterparts, yet still potent. Scientists hope that future drugs based on these molecules could provide new weapons against SARS-CoV-2......»»
Large field hospital study shows rapid COVID-19 test compares solidly with PCR detection
Researchers report that a rapid antigen detection test for SARS-CoV-2, the virus that causes COVID-19, proved more effective than expected when compared with virus detection rates using the established standard test, the polymerase chain reaction (PC.....»»
Natural infection and vaccination together provide maximum protection against COVID variants
A combination of vaccination and naturally acquired infection appears to boost the production of maximally potent antibodies against the COVID-19 virus, new research finds......»»
Researchers develop a world-first antibody-drug delivery system
It sounds like the stuff of science fiction: a man-made crystal that can be attached to antibodies and then supercharge them with potent drugs or imaging agents that can seek out diseased cells with the highest precision, resulting in fewer adverse e.....»»
Visualising cell structures in three dimensions in mere minutes
Viral pathogens like the SARS-CoV-2 coronavirus change the interior structure of the cells they infect. These changes occur at the level of individual cell components—the organelles—and can provide information on how viral diseases develop. Extre.....»»
Discovering new drugs, inspired by Darwinian theory
The body must constantly defend itself against bacteria and viruses. It generates millions of different antibodies, which are selected to recognize the enemy and trigger the best possible immune response. Scientists use these antibodies for therapeut.....»»
COVID"s Cardiac Connection
Coronavirus infections might cause lasting harm to the heart even in those who have never had symptoms -- Read more on ScientificAmerican.com.....»»