Activation of prodrug using protein-encased gold catalyst
As part of their efforts to devise ways to minimize the side effects of drugs for treating cancer, four RIKEN chemists have found a biocompatible way to convert compounds with low biological activity into anticancer drugs at tumors1......»»
Hospital prices for the same emergency care vary up to 16X, study finds
Hospitals' "trauma activation fees" are unregulated and extremely variable. Enlarge / Miami Beach, Fire Rescue ambulance at Mt. Sinai Medical Center hospital. ] (credit: Getty | Jeffrey Greenberg/) Since 2021, federal la.....»»
Key protein regulates immune response to viruses in mammal cells
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and.....»»
How a calcium-sensing protein multitasks
The calcium-sensing receptor is critical for maintaining healthy calcium levels, but CaSR is also well-known for its side hustles. The receptor is increasingly recognized for its ability to detect other ions and proteins and for its role in breast ca.....»»
A powerful technique for tracking a protein"s fleeting shape changes
Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate "movies" of changing protein structures and speeds of up to 50 frames per second......»»
New class of antimicrobials discovered in soil bacteria
Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species......»»
NHTSA upgrades probe into braking issues in 3 million Honda vehicles; 50 injuries reported
NHTSA said it has received 1,294 reported complaints alleging inadvertent activation resulting in “sudden vehicle deceleration.” There were 50 reported injuries and 31 crashes, NHTSA said......»»
NHTSA opens probe into braking issues in 3 million Honda vehicles
NHTSA said on Wednesday it had opened an engineering analysis to investigate reports of unexpected activation of automatic emergency braking systems on around 3 million American Honda Motor vehicles......»»
Trash to treasure—Researchers turn metal waste into catalyst for hydrogen
Scientists have found a way to transform metal waste into a highly efficient catalyst to make hydrogen from water, a discovery that could make hydrogen production more sustainable......»»
Illuminating the path to hearing recovery: Structural insights into a receptor protein"s role in auditory function
Researchers have worked to uncover the mysteries surrounding a specific receptor protein associated with hearing. Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republ.....»»
New time-resolved ultraviolet photodissociation mass spectrometry strategy for target protein stability analysis
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle structure dynamics is st.....»»
A single atom layer of gold—researchers create goldene
For the first time, scientists have managed to create sheets of gold only a single atom layer thick. The material has been termed goldene. According to researchers from Linköping University, Sweden, this has given the gold new properties that can ma.....»»
Deals: free $40 gift card with a Costco membership
For a limited time, score a free Costco Shop Card valued at $40 with a 1-year Gold Star Costco membership.Get a free Costco gift card with membership.The best Costco membership deal we've seen is back, delivering a free $40 digital Shop Card with a 1.....»»
Palladium nanocluster catalyst supports highly efficient and regioselective hydrogenation of epoxides
Alcohols are widely applied in life sciences and the chemical industry. Selective hydrogenation of epoxides using hydrogen molecules as a reductant is considered to be one of the most facile and atom-economical strategies for alcohol synthesis. Howev.....»»
Discovery of organic catalyst could lead to cheaper fuel cells
With atmospheric carbon dioxide at record highs, the search for clean-energy alternatives to the use of fossil fuels is growing increasingly urgent......»»
New catalyst allows energy-friendly ammonia production for fertilizers and alternative fuel
Researchers led by Satoshi Kamiguchi at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have discovered a greener way to produce ammonia, an essential compound used in fertilizers......»»
New study details how starving cells hijack protein transport stations
A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions......»»
Researchers develop method to extract useful proteins from beer-brewing leftovers
Researchers from Nanyang Technological University, Singapore (NTU Singapore), have created a method that extracts more than 80% of the available protein in grain leftovers from brewing beer, commonly known as brewers' spent grain......»»
Apple will allow activation of used parts in repairs by users & service shops
Apple is expanding its self-repair program procedures, and is adding the ability for consumers to use parts pairing to fully activate used parts in repairs — assuming they haven't been harvested from stolen devices.An Apple repair toolkitStarting i.....»»
A promising target for new RNA therapeutics now accessible
Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein mo.....»»
New protein imaging method supports the design of innovative new cancer drugs
Scientists have successfully used a new imaging technique to determine the structure and interactions of a protein complex that plays a significant part in the initiation and progression of cancer. They showed that it was possible to use a high-resol.....»»