A new tool to block protein-protein interactions
Inside cells, proteins constantly interact with each other to carry out different functions. For some diseases in which these functions are altered, blocking the binding between two or more proteins emerges as a possible therapeutic approach......»»
Scientists develop a new model of electric double layer
A new model accounts for a wide range of ion-electrode interactions and predicts a device's ability to store electric charge. The model's theoretical predictions align with the experimental results. Data on the behavior of the electric double layer (.....»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
A Tesla camera in Ohio captures heist as police discover a new crime-fighting tool
A Tesla owner in Toledo, Ohio, shared video footage of thieves stealing his brother's SUV, helping police recover the vehicle and make an arrest. Tesla external security cameras are assisting with similar crimes nationwide......»»
Prime Big Deal Days power tool deals: Up to $100 off DeWalt, Milwaukee, Bosch, and more
The return of Prime Big Deal Days power tool deals means massive discounts on brands like DeWalt and Milwaukee, but hurry because stocks may run out quickly......»»
DNA nanotechnology unravels complex protein interactions to inform cancer diagnostics
A team of researchers from NUS Institute for Health Innovation & Technology (iHealthtech), led by Associate Professor Shao Huilin and Associate Professor Brian Lim, has developed a first-of-its-kind technology to map out diverse protein interactions.....»»
Protein study reveals how the tiny shrew achieves a resting heart rate of 1,020 beats per minute
The shrew's resting heart rate can reach up to 17 beats per second, equivalent to about 1,020 beats per minute. In comparison, the average human resting heart rate is around 60 to 100 beats per minute, making the shrew's resting heart rate approximat.....»»
New tool can assess elderly dogs" frailty
Researchers from North Carolina State University have developed a tool that can aid owners and veterinarians in assessing an elderly dog's frailty. The tool—when coupled with simple assessments of body and muscle condition by the veterinarian—can.....»»
Retracing walrus ivory trade of Viking Age reveals early interactions between Europeans and Indigenous North Americans
By examining ancient walrus DNA, an international research team led by Lund University in Sweden have retraced the walrus ivory trade routes of the Viking Age. They found that Norse Vikings and Arctic Indigenous peoples were probably meeting and trad.....»»
Raman spectroscopy study decodes symbiotic interactions in marine algae
In a recent study, researchers from the Leibniz Institute of Photonic Technology (Leibniz IPHT) and the Friedrich Schiller University Jena have shown how they can non-invasively and non-destructively investigate the growth and interactions of the gre.....»»
SCCMSecrets: Open-source SCCM policies exploitation tool
SCCMSecrets is an open-source tool that exploits SCCM policies, offering more than just NAA credential extraction. SCCM policies are a key target for attackers in Active Directory environments, as they can expose sensitive technical information, incl.....»»
UPDF: The first AI PDF tool for Mac, iOS, and iPad that converts PDFs to mind maps
As AI continues to embed itself into our everyday lives and, now, Apple getting into the AI game with Apple Intelligence, the need for more intelligent, efficient tools is growing. With so much data to process, especially in PDFs, finding a solution.....»»
Trimer complex TaNF-Y balances grain yield and quality in wheat: Study
Breeding efforts have focused intensively on improving grain yield and quality in wheat (Triticum aestivum L.). Content and composition of grain starch and seed storage protein (SSP) are two critical factors that determine grain yield and quality. St.....»»
Tosint: Open-source Telegram OSINT tool
Tosint is an open-source Telegram OSINT tool that extracts useful information from Telegram bots and channels. It’s suited for security researchers, investigators, and others who want to gather insights from Telegram sources. Several law enforc.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
Another building block of life can handle Venus" sulfuric acid
Venus is often described as a hellscape. The surface temperature breaches the melting point of lead, and though its atmosphere is dominated by carbon dioxide, it contains enough sulfuric acid to satisfy the comparison with Hades......»»
New approach reveals details about aerosol properties from hard-to-sample areas in the atmosphere
The spatial distribution of ambient aerosol particles plays a huge role in aerosol–radiation–cloud interactions; however, not enough sampling has been done from the atmospheric boundary layer and lower free troposphere. This leaves large gaps in.....»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epi.....»»
Raycast is coming to the iPhone, but don’t expect a Mac-like experience
Raycast, the powerful launcher app for Mac, is officially in the works for iPhone (and Windows). The popular power user tool has been Mac-only since its debut, but the iPhone version is coming next year, and there’s a waitlist to join a beta sooner.....»»