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A new class of medicinal compounds that target RNA

A team of undergraduate and graduate chemistry students in Jennifer Hines' lab at Ohio University recently uncovered a new class of compounds that can target RNA and disrupt its function. This discovery identified a chemical scaffold that could ultim.....»»

Category: topSource:  physorgFeb 13th, 2023

Study identifies compounds that extend longevity of Japanese morning glory flowers

The longevity of plant flowers is controlled by genetically programmed mechanisms. After a certain amount of time after flowering, the expression of genes associated with programmed cell death is induced and cellular components such as proteins and n.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Study: Wildfires will make the land absorb much less carbon, even if warming is kept below 1.5°C

One of the aims of the Paris Agreement was to "pursue efforts" to keep global warming below 1.5°C, but even this ambitious target would not stop the land's ability to absorb carbon weakening as wildfires become fiercer and more frequent, according t.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Private US companies targeted by Stonefly APT

Undeterred by the indictment issued against one of its alleged members, North Korean APT group Stonefly (aka APT45) continues to target companies in the US, Symantec threat analysts warned. About Stonefly Also known as Andariel and OnyxFleet, Stonefl.....»»

Category: securitySource:  netsecurityRelated NewsOct 3rd, 2024

LEGO-inspired RNA sensors enable customizable gene control

A research team has developed an RNA-based sensor platform that can regulate gene expression in bacteria. Their findings were recently featured in the journal Advanced Science......»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

Researchers determine how a protein contributes to human immune defense against RNA viruses

An international research team led by Prof. Dr. Janosch Hennig from the University of Bayreuth has discovered how the TRIM25 protein contributes to defense against RNA viruses whose genetic material is contained as ribonucleic acid (RNA)......»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

One-minute phone breaks could help keep students more focused in class and better in tests

Phones can be useful tools in classrooms to remind students of deadlines or encourage more exchange between students and teachers. At the same time, they can be distracting. Students report using their phones for non-academic purposes as often as 10.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

AI model detects impervious surfaces in aerial images

In accordance with the German Sustainability Strategy, new impervious surfaces are to be limited to less than 30 hectares per day nationwide. In order to verify whether this target is met, it must be possible to monitor soil sealing at regular interv.....»»

Category: topSource:  physorgRelated NewsOct 1st, 2024

Seeing double: Designing drugs that target "twin" cancer proteins

Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»

Category: topSource:  physorgRelated NewsOct 1st, 2024

3D structure of key protein could advance development of hormone-free male contraceptive pill

Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»

Category: topSource:  theglobeandmailRelated NewsOct 1st, 2024

SCCMSecrets: Open-source SCCM policies exploitation tool

SCCMSecrets is an open-source tool that exploits SCCM policies, offering more than just NAA credential extraction. SCCM policies are a key target for attackers in Active Directory environments, as they can expose sensitive technical information, incl.....»»

Category: securitySource:  netsecurityRelated NewsSep 30th, 2024

Anti-bullying, sexual harassment resources increase in US schools but gaps remain

While violence prevention education has increased in U.S. schools, only one in 10 schools today require violence prevention discussions in class, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exh.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024

Advancing synthetic Ephedra-type alkaloids with a two-step enzymatic approach

Ephedra-type alkaloids, a class of naturally occurring compounds derived from plants in the genus Ephedra, have long held interest in the pharmaceutical industry due to their stimulant and airway widening effects. These alkaloids are used for the tre.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Semimetal-induced covalency achieves high-efficiency electrocatalysis for platinum intermetallic compounds

Compared with other types of batteries, proton exchange membrane fuel cells have the advantages of high discharge power and no pollution, which is also an important carrier for hydrogen energy conversion and utilization. Platinum intermetallic compou.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Medicinal tree successfully grown from 1,000-year-old seed found in cave

An international team of botanists, agriculturists and historians has successfully grown a mature tree from an ancient seed found in a cave in Israel. In their paper, published in the journal Communications Biology, the group describes where the seed.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Q&A: What"s behind the ban on cell phones in K-12 schools?

This school year, many of the nation's adolescents and teens are sitting in class without the device that can sometimes feel like an added appendage: their smartphones......»»

Category: topSource:  informationweekRelated NewsSep 24th, 2024

Hybrid RV with a solar roof can power your home in an emergency

The hybrid powertrain has a range of 500 miles. Enlarge / This is Thor and Harbinger's test bed for a new Class A hybrid RV. (credit: Thor) Electrification is moving through different parts of the automotive industry at.....»»

Category: topSource:  arstechnicaRelated NewsSep 23rd, 2024

Dealerships can start filing claims in CDK antitrust settlement

An Illinois federal judge has granted preliminary approval for CDK's agreement to pay $100 million to resolve a class-action antitrust lawsuit......»»

Category: topSource:  autonewsRelated NewsSep 23rd, 2024

Proof-of-concept study uses X-rays to target mock-up asteroids in a vacuum

An X-ray pulse may be able to vaporize the surface of an asteroid and change its trajectory, according to a proof-of-concept paper published in Nature Physics. A laboratory experiment that mimics the deflection of an asteroid model using this techniq.....»»

Category: topSource:  physorgRelated NewsSep 23rd, 2024

Elon Musk shares new target date for Starship voyage to Mars

But it's worth noting that the SpaceX CEO's forecasts often slip......»»

Category: topSource:  digitaltrendsRelated NewsSep 23rd, 2024

Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?

Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?.....»»

Category: topSource:  informationweekRelated NewsSep 21st, 2024