A new avenue for fighting drug-resistant bacteria
A small regulatory RNA found in many problematic bacteria, including Escherichia coli, appears to be responsible for managing the response of these bacteria to environmental stresses. Researchers see a promising avenue for more effective treatment of.....»»
Scientists discover how innate immunity envelops bacteria
The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now......»»
Targeting "selfish" bacteria could optimize inhibitors that fight antibiotic resistance
As strains of pathogens resistant to frontline antibiotics become more common worldwide, clinicians are more often turning to combination treatments that degrade this resistance as a first treatment option......»»
Signaling pathway discovery could lead to faster, more reliable human stem cell differentiation
A recent discovery has found a possible avenue to improve human health by better understanding how to engineer human stem cell differentiation......»»
Genetic mechanism unlocks a key secret behind disease infection in crops
Researchers have unraveled a key genetic mechanism behind the way pathogens infect crops, leading to new strategies for breeding resistant crop varieties against other pathogens carrying the same genetic mechanism......»»
Barnacle-inspired polymers could present new way to design antibiotics, researchers say
Scientific literature has shown that barnacles that cling to rocks at the seashore use naturally occurring chemicals to clear rock surfaces of bacteria in preparation for laying down their sticky "glue." Since bioengineering professor Abraham Joy's l.....»»
Drug makers can’t make knockoff weight-loss drugs anymore—and they’re mad
Compounding pharmacies could make knockoffs during shortage. But FDA says it's over. Compounding pharmacies are suing the Food and Drug Administration so they can keep making imit.....»»
Making micelles more effective for dye and drug dispersion through well-defined core-shell structures
Micelles are spherical molecular structures usually formed by amphiphilic molecules with block structure, which contain both hydrophilic and hydrophobic parts. The hydrophobic tails of these molecules cluster together to form a core, while the hydrop.....»»
How Chlamydia pneumoniae bacteria use molecular mimicry to manipulate the host cell
Bacteria that cause diseases, so-called pathogens, develop various strategies to exploit human cells as hosts to their own advantage. A team of biologists from Heinrich Heine University Düsseldorf (HHU), together with medical professionals and exper.....»»
A Major GLP-1 Drug Shortage Is Over. Some Patients Aren’t Celebrating
Mounjaro and Zepbound are now out of shortage. This should be good news—but because so many patients are taking compounded versions of these GLP-1 medications, it’s a complicated situation......»»
Experimental archaeology sheds light on skill and technique in Bronze Age spear combat
How can we tell whether and how a prehistoric weapon was used? How can we better understand the dexterity and combat skills involved in Bronze Age spear fighting?.....»»
Researchers design a drug capable of acting simultaneously against three different therapeutic targets
A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different thera.....»»
Research team develops metallodrug-antibiotic combination strategy to combat superbugs
Antimicrobial resistance (AMR) bacterial infections have become a serious problem threatening human health worldwide. The overuse of antibiotics has promoted drug-resistant mutations in bacteria, causing almost all clinically used antibiotics to deve.....»»
AI and quantum mechanics team up to accelerate drug discovery
Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects. That requirement for a meticulous fit means the creation of new dr.....»»
SCOTUS denial ends saga of Shkreli’s infamous 5,000% drug price scheme
The Supreme Court offered no explanation for denying the petition. The legal saga over Martin Shkreli's infamous 5,000 percent price hike of a life-saving anti-parasitic drug has.....»»
Trees" own beneficial microbiome could lead to discovery of new treatments to fight citrus greening disease
Citrus trees showing natural tolerance to citrus greening disease host bacteria that produce novel antimicrobials that can be used to fight off the disease, our recent study shows. We found the trees at an organic farm in Clermont, Florida......»»
Phage cocktail shows promise against drug-resistant bacteria
Researchers have a new battle tactic to fight drug-resistant bacterial infections. Their strategy involves using collections of bacteriophages, viruses that naturally attack bacteria. In a new study, researchers at the University of Chicago Pritzker.....»»
Quantum researchers come up with a recipe that could accelerate drug development
University of Copenhagen mathematicians have developed a recipe for upgrading quantum computers to simulate complex quantum systems, such as molecules. Their discovery brings us closer to being able to predict how new drugs will behave within our bod.....»»
Study sheds light on limitations of zooplankton for inactivating pathogen contaminated water
Scientists at The University of Texas at El Paso and Stanford University were recently surprised to find that the natural community of zooplankton—tiny, aquatic animals known to graze on bacteria—present in freshwater and saltwater do not clean w.....»»
Wastewater bacteria can break down plastic for food, yielding new possibilities for cleaning up plastic waste
Researchers have long observed that a common family of environmental bacteria, Comamonadacae, grow on plastics littered throughout urban rivers and wastewater systems. But exactly what these Comamonas bacteria are doing has remained a mystery......»»
These New Biomaterials Can Help Decarbonize Fashion and Construction
Designers are imagining a future where bacteria powers both clothing and cement—and their ideas are coming to a shop near you......»»