A gene in tuberculosis bacteria is found essential for siderophore secretion and virulence
Lei Zhang, Ph.D., and Michael Niederweis, Ph.D., of the University of Alabama at Birmingham have made what they call "a major step" in understanding how Mycobacterium tuberculosis acquires iron from its human host—a process essential for the pathog.....»»
Mystery CRISPR unlocked: A new ally against antibiotic resistance?
CRISPR-Cas systems have revolutionized biotechnology by offering ways to edit genes like a pair of programmable scissors. In nature, bacteria use these systems to fight off deadly viruses. A recent international collaboration led by the University of.....»»
Allyship is essential to new mothers returning to work, says study
Returning to work after parental leave can be one of the most challenging experiences for any parents, especially mothers, to navigate. Fortunately, there are simple, kind and thoughtful ways in which organizational members—regardless of formal sta.....»»
Coupling quantum mechanical simulations and AI paves way for screening new superconductors
Superconductors are materials that conduct electricity without resistance and are essential for several technological advancements, which include medical imaging and energy-efficient technology. However, most known superconductors operate under extre.....»»
Researchers discover new family of bacteria with high pharmaceutical potential
Most antibiotics used in human medicine originate from natural products derived from bacteria and other microbes. Novel microorganisms are therefore a promising source of new active compounds, also for the treatment of diseases such as cancer or vira.....»»
Fine roots make the difference in metabolomes and microbiomes
Bacteria and fungi live together on the surface of plant roots, which can promote symbiotic interactions with the plant. Plant roots that are especially fine can support various niches for their microbial proliferations, but traditionally, microbiome.....»»
Persistent strain of cholera defends itself against forces of change, scientists find
A deadly strain of cholera bacteria that emerged in Indonesia back in 1961 continues to spread widely to this day, claiming thousands of lives around the world every year, sickening millions, and with its persistence, baffling scientists......»»
Researchers clone "half-tendrilless" gene locus in pea mutant afila
Pea is the fourth largest edible legume crop in the world and is widely cultivated throughout the world. Several classical leaf mutants have been identified in peas, including unifoliata (uni), afila (af), tendril-less (tl), cocholeata (coch), stipul.....»»
More children gain hearing as gene therapy for profound deafness advances
The therapy treats a rare type of deafness, but experts hope it's a "jumping point." Enlarge / Opal Sandy (center), who was born completely deaf because of a rare genetic condition, can now hear unaided for the first time after r.....»»
Researchers shed new light on carboxysomes in key discovery that could boost photosynthesis
A research team led by the Hong Kong University of Science and Technology (HKUST) has discovered how carboxysomes—carbon-fixing structures found in some bacteria and algae—work. The breakthrough could help scientists redesign and repurpose the st.....»»
New rhizobia-diatom symbiosis solves long-standing marine mystery
Nitrogen is an essential component of all living organisms. It is also the key element controlling the growth of crops on land, as well as the microscopic oceanic plants that produce half the oxygen on our planet. Atmospheric nitrogen gas is by far t.....»»
Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic mo.....»»
Exploring lysosomal biology: Current approaches and methods
Lysosomes are critical for cellular degradation, characterized by their acidic pH and array of hydrolytic enzymes. They degrade materials through endocytosis, phagocytosis, and autophagy, recycling essential components. Lysosomes also participate in.....»»
Marine bacteria team up to produce a vital vitamin
A German-American research team led by microbiologist Dr. Gerrit Wienhausen from the University of Oldenburg (Germany) has come an important step closer to a better understanding of highly complex interactions between marine microorganisms. The resea.....»»
Limited adaptability is making freshwater bacteria vulnerable to climate change
Freshwater bacteria with small genomes frequently undergo prolonged periods of adaptive stagnation. Based on genomic analyses of samples from Lake Zurich and other European lakes, researchers at the University of Zurich have uncovered specific evolut.....»»
5 Key Elements of a Successful Project Plan
Intro: Forgetting or neglecting an essential element of a project plan can cause the whole thing to derail. For those on the cusp of launching something big, here are the key pillars you need to be laser focused on and set firmly in place, so the w.....»»
YUM List Installed Packages Guide: Maximizing its Potential
YUM utility is now an essential tool for any tech person juggling with packages in Linux systems. But the primary question is, are we wielding this tool to its fullest capacity? Let’s learn how yum list installed packages can help you cut down your.....»»
Study underscores new strategies to fight drug-resistant bacteria
Several billion years ago, a genetic arms race began between bacteria and their viral killers. This seemingly eternal struggle continues today, with implications for diseases killing tens of thousands of people around the world each year......»»
Chimps shown to learn and improve tool-using skills even as adults
Chimpanzees continue to learn and hone their skills well into adulthood, a capacity that might be essential for the evolution of complex and varied tool use, according to a study published May 7 in the open-access journal PLOS Biology by Mathieu Malh.....»»
Nanoparticle researchers develop microfluidic platform for better delivery of gene therapy for lung disease
Drug delivery researchers at Oregon State University have developed a device with the potential to improve gene therapy for patients with inherited lung diseases such as cystic fibrosis......»»
How to trade in Manor Lords
Trading is essential in Manor Lords for making sure your early town has adequate supplies, but other traders will be scarce until you do a few things first......»»