A better reference genome for the rhesus macaque
A large team of researchers from the U.S., Italy and Germany has developed a new and improved reference genomic assembly for the rhesus macaque. In their paper published in the journal Science, the group describes using advanced sequencing techniques.....»»
Taxonomy goes viral: Experts publish a new set of consensus principles to classify the virosphere
The official body charged with virus classification has released four new principles that bring order to the viral world. This provides a unified framework that will enable all viruses to be classified, something vitally needed as genome technologies.....»»
Neuralink transported brain implants covered in pathogens, group alleges
This is the second federal probe for Musk's brain-computer interface company. Enlarge / Pager, a 9-year-old Macaque, plays MindPong with his Neuralink. (credit: YouTube/NeuraLink) The US Department of Transportation is i.....»»
When editing bacteria with CRISPR, less is more
Systematically attenuating DNA targeting activity can achieve CRISPR-driven editing in bacteria, greatly boosting colony counts and even increasing the frequency of precise genome editing. This was shown in a study of the Helmholtz Institute Würzbur.....»»
Researchers decode 95.6% of the genome of Nicotiana benthamiana
The plant Nicotiana benthamiana, from the Solanaceae family, is one of the most widely used experimental models in plant science. In 2020, a research group at Nagoya University in Japan reported that N. benthamiana could be grafted with plants from d.....»»
Reference epigenome reveals transcription and chromatin state reprogramming during wheat embryogenesis
Embryogenesis is one of the most fundamental and remarkable processes in both animals and plants. It's amazing that after fertilization, a single maternal egg cell can develop into an organism with a multilayered body plan only in just a few weeks. C.....»»
Label-free imaging of red blood cells and oxygenation with color TSFG microscopy
Cells and tissues rely on the circulation of red blood cells (RBCs) for oxygen supply. Two-photon (2P) microscopy is a reference technique for measuring RBC microcirculation and blood oxygenation using exogenous phosphorescent probes. It is increasin.....»»
UMC, Cadence collaborate on 3D-IC hybrid bonding reference flow
United Microelectronics (UMC) and Cadence Design Systems have jointly announced that the Cadence 3D-IC reference flow has been certified for UMC's chip stacking technologies......»»
Stunningly detailed blueprint revealed of viral genome replication machinery
RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell......»»
Boosting efficiency of genome editing procedures to modify initially inaccessible DNA sequences
In the course of optimizing key procedures of genome editing, researchers from the department of Developmental Biology / Physiology at the Center for Organismal Studies of Heidelberg University have succeeded in substantially improving the efficiency.....»»
Power of cancer drugs may see boost by targeting newly identified pathway
Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome—a cell's complete set of DNA—is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are di.....»»
Study reveals dynamics of DNA ligation during genome replication
Unconnected strands of DNA must be sealed together during genome replication and repair, and a new KAUST-led investigation shows how the fastening enzyme involved gets the job done......»»
World-first computational reconstruction of a virus in its biological entirety
An Aston University researcher has created the first ever computer reconstruction of a virus, including its complete native genome......»»
From octopus to elephant: A molecular zoo of epigenetics
Our genes are encoded in the DNA sequence of the genome, which is highly similar across the diverse cell types of our body. Yet, each cell can only access those genes that are in an epigenetically permissive state. The epigenome thus provides a form.....»»
Modified CRISPR-based enzymes improve the prospect of inserting entire genes into the genome
Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient's mutation would be impractical and costly......»»
SRM 915c calcium carbonate mass fraction standard
This standard reference material from the National Institute of Standards and Technology (NIST) will help calibrate procedures for calcium determinations used in clinical analysis and for routine critical evaluation of the daily working standards app.....»»
Standard reference cantilevers for atomic force microscopy spring constant calibration
Atomic force microscopy (AFM) is a popular technique for interrogating surfaces on the micro and nano scales. The most common use for AFM is imaging; however, there are a variety of more specialized AFM techniques that can be used to determine electr.....»»
Researchers produce first-ever toolkit for RNA sequencing analysis using a "pantranscriptome"
Analyzing a person's gene expression requires mapping their RNA landscape to a standard reference to gain insight into the degree to which genes are "turned on" and perform functions in the body. But researchers can run into issues when the reference.....»»
Evolution of uniquely human DNA was a balancing act, study concludes
Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences. HARs were stable in mammals for millennia but quickly changed in early humans. Sc.....»»
Reference to xrOS found in Apple Devices for Windows app preview
Preview versions of Apple Music, Apple TV, and Apple Devices for Windows apps have been discovered in the Microsoft Store, and hidden in the code are references to Apple's upcoming mixed-reality operating system.A render of a potential Apple headset.....»»
Sharp is bringing one of the first OLED Roku TVs to the U.S. in 2023
Now that Roku has released a reference design for an OLED Roku TV, Sharp has indicated its intention to sell one in the U.S......»»