"ZIP" codes tell RNA molecules how to get to their designated locations
They say that life comes without an instruction manual, but that's not entirely true. Each cell in our bodies lives according to instructions issued by its DNA in the form of RNA molecules. RNA was recently thrust into the limelight as the basis of i.....»»
Targeting "undruggable" diseases: Researchers reveal new levels of detail in targeted protein degradation
Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and ne.....»»
Stunning aurorae visible around the world caused by solar storms
Beautiful aurorae were visible in locations around the world this week due to increased activity from the sun......»»
How to setup passkeys in Apple Passwords app
Beginning with iOS 18, iPadOS 18, macOS Sequoia, and visionOS 2, the Passwords app allows you to manage your passwords, passkeys, and verification codes. Passwords app interface Creating passkeys Passkeys are a password alternative designed to offer.....»»
High-resolution structural data shows how a supercomplex links mRNA translation and decay
Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena Conti and her team at the Max Planck Institute of Biochemistry in Martinsried near Munich have now been able to show that the.....»»
A look into "mirror molecules" may lead to new medicines
A University of Texas at Dallas chemist and his colleagues have developed a new chemical reaction that will allow researchers to synthesize selectively the left-handed or right-handed versions of "mirror molecules" found in nature and assess them for.....»»
The unintended consequences of brick-and-mortar"s decline
Lately, many big retail brands have been closing physical locations, in what has become known as the "retail apocalypse." Whether the stated reason is declining revenue, or concerns related to "shrinkage" and employee safety in some cities, the impac.....»»
Making micelles more effective for dye and drug dispersion through well-defined core-shell structures
Micelles are spherical molecular structures usually formed by amphiphilic molecules with block structure, which contain both hydrophilic and hydrophobic parts. The hydrophobic tails of these molecules cluster together to form a core, while the hydrop.....»»
Auto auctions in Florida cancel sales days, more dealerships close ahead of Hurricane Milton
Hurricane Milton prompted wholesale auto auction providers to cancel planned sales days at certain storm-warned locations in Florida this week......»»
Key molecule in wound healing identified through mapping of long non-coding RNA molecules
A new study from Karolinska Institutet and the Chinese Academy of Medical Sciences has identified an RNA molecule that is important for skin wound healing. The research, published in Nature Communications, may have implications for the treatment of h.....»»
H-E-B caves to the pressure and begins rolling out Apple Pay to all stores
After kicking off a pilot program in July, H-E-B has announced that it will roll out support for tap-to-pay platforms like Apple Pay to all of its locations. H-E-B operates over 300 locations across Texas, making it one of the largest grocery store c.....»»
Home Depot quietly begins rolling out Apple Pay support
Just a few hours ago, I wrote about H-E-B finally caving to the pressure and rolling out Apple Pay to all of its locations. As it turns out, H-E-B isn’t alone in this change. According to multiple 9to5Mac readers and reports across social media, Ho.....»»
Anti-glitches detected in gamma-ray pulsar PSR J1522-5735
By analyzing the data from NASA's Fermi Gamma-ray Space Telescope, Russian astronomers have detected anti-glitches in a gamma-ray pulsar designated PSR J1522-5735. The discovery, published September 28 on the pre-print server arXiv, makes PSR J1522-5.....»»
AI and quantum mechanics team up to accelerate drug discovery
Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects. That requirement for a meticulous fit means the creation of new dr.....»»
Nobel Prize in medicine awarded for discovery of microRNAs, the molecules that control our genes
Two scientists, Victor Ambros (UMASS Chan Medical School in the US) and Gary Ruvkun (Harvard Medical School in the US), have won the 2024 Nobel prize in medicine or physiology......»»
Fused molecules could serve as building blocks for safer lithium-ion batteries
By fusing together a pair of contorted molecular structures, Cornell researchers have created a porous crystal that can uptake lithium-ion electrolytes and transport them smoothly via one-dimensional nanochannels—a design that could lead to safer s.....»»
Quantum researchers come up with a recipe that could accelerate drug development
University of Copenhagen mathematicians have developed a recipe for upgrading quantum computers to simulate complex quantum systems, such as molecules. Their discovery brings us closer to being able to predict how new drugs will behave within our bod.....»»
How to use the Apple Passwords app
The latest Apple OS updates (iOS 18, iPadOS 18, macOS Sequoia) have introduced a standalone Passwords app, to make users’ passwords, passkeys, Wi-Fi passwords, and verification codes easily accessible. You can access the Passwords app on your i.....»»
All stamp locations in The Legend of Zelda: Echoes of Wisdom
There are plenty of sidequests in The Legend of Zelda: Echoes of Wisdom, but the big one is the stamp-collecting game. Here is where you can find every stamp......»»
LEGO-inspired RNA sensors enable customizable gene control
A research team has developed an RNA-based sensor platform that can regulate gene expression in bacteria. Their findings were recently featured in the journal Advanced Science......»»
Researchers determine how a protein contributes to human immune defense against RNA viruses
An international research team led by Prof. Dr. Janosch Hennig from the University of Bayreuth has discovered how the TRIM25 protein contributes to defense against RNA viruses whose genetic material is contained as ribonucleic acid (RNA)......»»