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"Like a magic trick," certain proteins pass through cell walls

For decades, scientists have wondered how large molecules such as proteins pass through cell walls, also known as plasma membranes, without leaving a trace. That ability is part of what makes certain drugs—including some cancer treatments and the C.....»»

Category: topSource:  physorgOct 20th, 2021

A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins

For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»

Category: topSource:  physorgRelated News7 hr. 9 min. ago

Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell

The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»

Category: topSource:  physorgRelated News10 hr. 41 min. ago

Scientists regenerate neural pathways in mice with cells from rats

Two independent research teams have successfully regenerated mouse brain circuits in mice using neurons grown from rat stem cells. Both studies, published April 25 in the journal Cell, offer valuable insights into how brain tissue forms and present n.....»»

Category: topSource:  physorgRelated News10 hr. 41 min. ago

Advanced cell atlas opens new doors in biomedical research

Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about huma.....»»

Category: topSource:  physorgRelated News10 hr. 41 min. ago

Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater

Scientists from Nanyang Technological University, Singapore (NTU Singapore) and Temasek Polytechnic have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a "single cell protein" cultivated from microbes in.....»»

Category: topSource:  physorgRelated News10 hr. 41 min. ago

Spotify: Apple has ‘defied’ the EU by blocking latest update with pricing info [U: Apple response]

Yesterday we learned that Spotify decided to pass on Apple’s new EU terms that would allow it to use alternative payment methods due to the Core Technology Fee. Instead, it submitted an app update with pricing info and details on how to subscribe o.....»»

Category: topSource:  marketingvoxRelated News13 hr. 9 min. ago

Spotify"s second iOS app update attempt in EU fails to pass App Store review

A update to Spotify's app in the App Store is on hold, after the streaming service failed to follow rules allowing links to external sites for purchases.Spotify's app in the EUApple has already made a number of changes to its App Store rules, primari.....»»

Category: appleSource:  appleinsiderRelated NewsApr 24th, 2024

Researchers unveil PI3K enzyme"s dual accelerator and brake mechanisms

A group of researchers have expanded conventional knowledge on a critical enzyme that controls cell migration. In a publication in the journal Nature Communications, they reported that phosphoinositide 3-kinase (PI3K) not only acts as an accelerator.....»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Unveiling the mysteries of cell division in embryos with timelapse photography

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis are well-studied in the so-called somatic cells—the cells that have a specialized function, like skin and muscle cells—they remain elusive in the first cells of.....»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Scientists study lipids cell by cell, making new cancer research possible

Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors. Scientists are celebrating a new technique that lets them study the fatty contents of cancer cells, one by one......»»

Category: topSource:  theglobeandmailRelated NewsApr 23rd, 2024

Best Verizon new customer deals: Galaxy S24, iPhone and more

Are your monthly cell phone bills bleeding you dry? Save some cash with these Verizon new customer deals......»»

Category: topSource:  digitaltrendsRelated NewsApr 23rd, 2024

Researchers create artificial cells that act like living cells

In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that look and act like cells f.....»»

Category: topSource:  theglobeandmailRelated NewsApr 23rd, 2024

Supercomputer simulation reveals new mechanism for membrane fusion

An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse......»»

Category: topSource:  physorgRelated NewsApr 23rd, 2024

Researchers report on mechanisms of gene regulatory divergence between species

Closely related animal species can look physically different, but you might be surprised to learn that those differences can result not only from DNA sequence changes that alter proteins' structure or function, but also because changes in the DNA aff.....»»

Category: topSource:  physorgRelated NewsApr 23rd, 2024

Researchers map protein network dynamics during cell division

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the.....»»

Category: topSource:  physorgRelated NewsApr 22nd, 2024

9to5Mac Overtime 015: Respect the mute switch

Jeff and Fernando talk about AltStore launching in the EU, the Delta Nintendo Emulator officially arriving in the App Store, iOS 17.5 beta changes and features, the upcoming 12.9-inch iPad Air with mini LED display, iPad Magic Keyboard conjecture, fl.....»»

Category: topSource:  marketingvoxRelated NewsApr 20th, 2024

A $20 Chromecast with Google TV is perfect for this one reason

If you travel at all, you should consider a $20 Chromecast with Google TV. It's just tough to pass up at that price......»»

Category: topSource:  digitaltrendsRelated NewsApr 19th, 2024

LastPass users targeted by vishing attackers

The CryptoChameleon phishing kit is being leveraged by vishing attackers looking to trick LastPass users into sharing their master password. “Initially, we learned of a new parked domain (help-lastpass[.]com) and immediately marked the website.....»»

Category: securitySource:  netsecurityRelated NewsApr 19th, 2024

Light show in living cells: New method allows simultaneous fluorescent labeling of many proteins

Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge—especially in living cells, as the required fluorescent labeling had to be individually attached to each p.....»»

Category: topSource:  theglobeandmailRelated NewsApr 19th, 2024

LastPass users targeted in phishing attacks good enough to trick even the savvy

Campaign used email, SMS, and voice calls to trick targets into divulging master passwords. Enlarge (credit: Getty Images) Password-manager LastPass users were recently targeted by a convincing phishing campaign that use.....»»

Category: topSource:  arstechnicaRelated NewsApr 18th, 2024