Ground-breaking bacteria-killing viruses unite with antibiotics to fight devastating antibiotic-resistant bacteria
Mycobacterium abscessus, a relative of the bacteria that cause tuberculosis and leprosy, is responsible for particularly severe damage to human lungs and can be resistant to many standard antibiotics, making infections extremely challenging to treat......»»
Thousands of Brits sign up to save condemned alpaca Geronimo
Tens of thousands of people in Britain have signed a petition to save an alpaca named Geronimo, who the government insisted Friday must be euthanised after testing positive for bovine tuberculosis (bTB)......»»
Could a TB vaccine protect the elderly from severe COVID?
Scientists suspect that a century-old tuberculosis vaccine might be able to protect older adults against the worst ravages of COVID-19......»»
Cell-analysis technique could combat tuberculosis
Researchers have developed a way to analyze how individual immune cells react to the bacteria that cause tuberculosis. It could pave the way for new vaccine strategies and provide insights into fighting other infectious diseases......»»
Cell-analysis technique could combat tuberculosis
A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the wo.....»»
Progress towards new treatments for tuberculosis
A new study has uncovered how cells infected with tuberculosis bacteria can die, and that using new medicines to enhance particular forms of cell death decreased the severity of the disease in a preclinical model......»»
TB immune response discovery could significantly reduce disease harm
A pioneering study has discovered the presence of a harmful inflammatory protein in patients with symptomatic tuberculosis (TB). Researchers say, by targeting the IL-17 cytokine, a component produced naturally by the immune system in response to infe.....»»
Tailor-made therapy of multi-resistant tuberculosis
The successful treatment of multidrug-resistant tuberculosis requires clarification in advance as to which antibiotics the pathogens are resistant to. Classic testing is very time-consuming and delays the start of therapy. Researchers have now prepar.....»»
Starving tuberculosis of sugars may be a new way to fight it
Tuberculosis is a devastating disease that claims over 1.5 million lives each year. The increase in TB cases that are resistant to the current antibiotics means that novel drugs to kill Mycobacterium tuberculosis (Mtb) are urgently needed. Researcher.....»»
Disrupted movement makes macrophages more lethal to tuberculosis bacteria
Macrophages—the front line of our immune system—protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophage.....»»
The tuberculosis pathogen releases its toxin by a novel protein transport system
Six years ago, Michael Niederweis, Ph.D., described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis. This toxin, tuberculosis necrotizing toxin, or TNT, became the founding member of a novel class of previously unrecogni.....»»
New study explains Mycobacterium tuberculosis high resistance to drugs and immunity
A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions by utilizing rubredoxin B, a protein from a rubre.....»»
Rising Sika deer populations linked to bovine tuberculosis infections
New research suggests Ireland's increasing populations of Sika deer may be linked to local outbreaks of TB infection in cattle......»»
New discoveries on deadly fungus—possibly a key for treatment
Aspergillus fumigatus kills as many people as malaria and tuberculosis, but is less known. It is found everywhere, for example in the soil or in our compost, but is not normally dangerous to healthy people......»»
Ancient DNA reveals clues about how tuberculosis shaped the human immune system
A new study employing ancient human DNA reveals how tuberculosis has affected European populations over the past 2,000 years, specifically the impact that disease has had on the human genome. This work has implications for studying not only evolution.....»»
Skeletons reveal humans evolved to fight pathogens
As COVID-19 impacts lives around the world—a new skeleton study is reconstructing ancient pandemics to assess human's evolutionary ability to fight off leprosy, tuberculosis and treponematoses with help from declining rates of transmission when the.....»»
Study could explain tuberculosis bacteria paradox
Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers and infectious disease experts......»»
Study could explain tuberculosis bacteria paradox
Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS)......»»
Tuberculosis: New biomarker indicates individual treatment duration
The treatment of tuberculosis (TB) is long and demanding. In particular, in cases of resistant tuberculosis, the WHO generally recommends a standard treatment duration of at least 18 months, as there are no reliable biomarkers for an early terminatio.....»»
TB study reveals potential targets to treat and control infection
Researchers may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb). Using single-cell RNA sequencing (scRNAseq), a next-generation sequencing technology, scientists were able to fur.....»»