Why synonymous mutations are not always silent
New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn State chemists modeled how ge.....»»
The silent conversations of plants
This morning, my six-year-old came into our bedroom and started reading a story from a book. She followed each word on the page, slowly forming full sentences. Sometimes she stumbled and asked for help with some "funny words," but by the end of the b.....»»
Virtual laboratory allows scientists to simulate specific decreases in gene activity
Imagine you're looking at millions upon millions of mysterious genetic mutations. With CRISPR gene-editing technology, a select few of these mutations might have therapeutic potential. However, proving it would mean many thousands of hours of lab wor.....»»
New technique boosts mutation rates in fruit flies for genetics research
A new technique, TF-High-Evolutionary (TF-HighEvo), allows large-scale assessment of de-novo mutations in multicellular organisms. Developed in collaboration with researchers from the European Molecular Biology Laboratory (EMBL) and the Friedrich Mie.....»»
This massive Silent Hill 2 fan project is getting its final update
Silent Hill 2: Enhanced Edition, once one of the best ways to play the horror classic on PC, is coming to an end ahead of the remake's release......»»
"Silent" mutations found to have repercussions beyond their own gene
Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide in a codon is switched. In non-synonymous muta.....»»
From rhino horn snuff to pangolin livestock feed: A half-century of patents reveals the wildlife trade"s evolution
The bright blue blood of the horseshoe crab is used around the world to detect bacterial contamination in vaccines. Synonymous with luxury, sturgeon caviar has been patented as an antidote to impotency in China. Rhino horn is used in traditional Asia.....»»
Hollow Knight: Silksong: trailer, gameplay details, and more
Things have gone mostly silent since the announcement of Hollow Knight: Silksong, but there have been morsels of info. Here's everything we know about the game......»»
Arm-mounted haptics could make future iPhone notifications more discreet
Even silent alerts can be audible if an Apple Watch haptic engine is too powerful, but Apple has plans to make notifications entirely private.Detail from the patent. Notice the armband and possibly an Apple Bracelet tooYou're at a meeting and it's ti.....»»
Waymo’s honking robocars finally fall silent
In one of the more bizarre technology tales of the year, Waymo has apparently finally got its honking robocars to be quiet......»»
Silent Hill 2 remake: release date, trailers, gameplay, and more
There was a rumor here. It's gone now. That's right, the Silent Hill 2 remake rumors have faded into the fog and become a reality. Here's everything we know......»»
I was a Silent Hill 2 remake skeptic until I played its first 3 hours
After three hours with Silent Hill 2, we're no longer skeptical about the upcoming remake......»»
New tools for fungicide resistance detection
Researchers at the Center for Crop and Disease Management (CCDM) have developed a new method for detecting fungicide resistance, enabling them to detect multiple mutations, both known and novel, in just one test......»»
Breaking down online shopping"s silent threat
Breaking down online shopping"s silent threat.....»»
Double whammy antibiotic makes antibiotic resistance much harder—new study
Most antibiotics are natural products of bacteria and other microorganisms from the environment. They are part of a silent chemical warfare among microorganisms in soils, rivers and seas right now. The fact that they are natural products that have be.....»»
Inbred-parent–based cassava hybrids promise enhanced efficiency and resilience
A research team has proposed inbred-parent–based hybrid cassava breeding to overcome the challenges of heterozygous parent use, aiming to transform cassava breeding by purging deleterious mutations and utilizing heterosis. This approach leverages s.....»»
The silent spreader: Reassessing the role of mice in leptospirosis risk
Emerging research highlights mice as a critical yet underestimated source of leptospirosis, emphasizing the need for improved strategies to control the spread of the infectious disease......»»
New nanoparticle delivery method targets sickle cell mutations in bone marrow
Current gene therapies to treat sickle cell disease are complex, time-consuming, and are sometimes linked to serious side effects like infertility or blood cancer. To address these challenges, Johns Hopkins researchers have developed special nanopart.....»»
Splitgate 2: release date window, trailers, gameplay, and more
After going silent for years, Splitgate 2 has appeared from nowhere to bring portals back to shooters. This is everything we know about this unique PvP game......»»
Team develops new one-step method to make multiple edits to a cell"s genome
Genome editing has become a widely adopted technology to modify DNA in cells, allowing scientists to study diseases in the lab and develop therapies that repair disease-causing mutations. However, with current approaches, it's only possible to edit c.....»»
Konami shares first trailer for Return to Silent Hill
Konami has shared the first trailer for Return to Silent Hill, the upcoming horror movie based on the video game Silent Hill 2......»»