Unfolding the blindness proteins through fly eyes
Every 6 minutes someone is told they're going blind. One of the major causes of human blindness is a disease called Retinitis Pigmentosa (RP), which causes progressive degeneration of the retina and vision loss. Approximately one-tenth of Retinitis.....»»
Probing proton pumping: New findings on protein folding in bacteriorhodopsin
When it comes to drug development, membrane proteins play a crucial role, with about 50% of drugs targeting these molecules. Understanding the function of these membrane proteins, which connect to the membranes of cells, is important for designing th.....»»
Q&A: Research visualizes a precise mechanism for how cells sort their trash
For decades it has been an open question in the ubiquitin research field how proteins are labeled as being defective or unneeded. In a recent study Brenda Schulman, Director at the Max Planck Institute (MPI) of Biochemistry, and Gary Kleiger, Chair o.....»»
Replacing animal-based foods with alternative proteins would unlock land for carbon removal, say researchers
Researchers report that replacing 50% of animal products with alternative proteins by 2050 could free up enough agricultural land to generate renewable energy equivalent in volume to today's coal-generated power while simultaneously removing substant.....»»
Decoding the molecular networks of early human development
New international research shines a light on the role of transcription factors during early embryonic development. Transcription factors are proteins that are critical for gene regulation. The study unveiled more than 1,000 protein–protein interact.....»»
Manipulating host defenses: Unveiling the role of a powdery mildew effector in grapevine infection
Powdery mildew, caused by Erysiphe necator, is a significant threat to grapevine health, utilizing secreted effector proteins (CSEPs) to suppress plant defenses. Despite knowledge of plant immune mechanisms, the specific roles of E. necator's CSEPs i.....»»
New findings from JWST: How black holes switched from creating to quenching stars
Astronomers have long sought to understand the early universe, and thanks to the James Webb Space Telescope (JWST), a critical piece of the puzzle has emerged. The telescope's infrared detecting "eyes" have spotted an array of small, red dots, identi.....»»
Preclinical study uncovers two proteins" crucial role in causing cancer cell growth
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. The study is published i.....»»
Researchers use supercomputer to determine whether "molecules of life" can be formed naturally in right conditions
Basic biology textbooks will tell you that all life on Earth is built from four types of molecules: proteins, carbohydrates, lipids, and nucleic acids. And each group is vital for every living organism......»»
Scientists successfully simulate protein complex that initiates fertilization
Researchers at ETH Zurich recently developed highly realistic simulations of the proteins on sperm and egg cells coupling together before they fuse. These findings enabled the research team to solve several mysteries of fertilization at once, which c.....»»
Continental eyes more innovation amid EV, software transition
Continental sees significant growth potential in its offerings for software-defined vehicles, advanced driver-assistance systems and infotainment displays amid rocky EV transition......»»
Researchers develop method to map interactions of specific RNA regions in live cells
The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct intera.....»»
New research brings order to disordered proteins
Protein molecules lie at the heart of biology. Our typical understanding of proteins states that each type of protein has a specific three-dimensional shape that enables it to perform its function. This dogma is challenged by intrinsically disordered.....»»
Computer-designed proteins allow for tunable hydrogels that can form both inside and outside of cells
When researchers want to study how COVID makes us sick, or what diseases such as Alzheimer's do to the body, one approach is to look at what's happening inside individual cells. Researchers sometimes grow the cells in a 3D scaffold called a "hydrogel.....»»
Team develops a non-allergenic wheat protein for growing better cultivated meat
As the world's population increases, cultivated or lab-grown meat—animal muscle and fat cells grown in laboratory conditions—has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to g.....»»
New AI model designs proteins to deliver gene therapy
Researchers at the University of Toronto have used an artificial intelligence framework to redesign a crucial protein involved in the delivery of gene therapy......»»
Animals see the world in different colors than humans: New camera reveals what this looks like
If you've ever wished you could see the world though the eyes of another animal, we have good news for you. We also wondered about that and, being scientists who specialize in color vision, have created a solution: a camera system and software packag.....»»
New simulation tool advances molecular modeling of biomolecular condensates
A University of Massachusetts Amherst team has made a major advance toward modeling and understanding how intrinsically disordered proteins (IDPs) undergo spontaneous phase separation, an important mechanism of subcellular organization that underlies.....»»
New method for incorporating structurally unusual amino acids into proteins
A team of biochemists at the Medical Research Council Laboratory of Molecular Biology at Cambridge has developed a new method to incorporate structurally unusual amino acids into proteins by using bacteria. The method is described in the journal Natu.....»»
Novel camera system lets us see the world through eyes of birds and bees
It captures natural animal-view moving images with over 90 percent accuracy. A new camera system and software package allows researchers and filmmakers to capture animal-view videos. Credit: Vasas et al., 2024. Who among us hasn't w.....»»
Fingerprinting biomolecules with the help of sound
A team of researchers from the Institute for Optoelectronic Systems and Microtechnology at Universidad Politécnica de Madrid (UPM) has designed a biosensor capable of identifying proteins and peptides in quantities as low as a single monolayer. For.....»»