The soft "spaghetti" of proteins that"s essential for the resistance of bacteria
Bacteria are increasingly resistant, especially to antibiotics, which is a major global health problem. An example, related to the pandemic? Covid weakens hospitalized people so much that we are now witnessing an upsurge in bacterial infections (resi.....»»
Researchers decipher how an enzyme modifies the genetic material in the cell nucleus
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»
New structures offer insight into how a bacterial motor powers bacterial chemotaxis, a key infectious process
Bacteria existed for millennia before humans and have been infecting us from the beginning. Although we can treat infections through pharmaceuticals, bacteria continue to become resistant to treatment thanks to their rapid evolution. Bacterial infect.....»»
A systematic review of three key sugar metabolism proteins: HXK, SnRK1 and TOR
Sugar signaling is one of the most important regulatory signals for plant growth and development, and its metabolic network contains many regulatory factors. Sugar signaling molecules regulate cellular activities and organismal development by interac.....»»
A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»
How to reset the Nanoleaf Skylight
You can perform a soft reset or factory reset on the Nanoleaf Skylight, and neither task should take more than a few minutes. Here's what you need to know......»»
Supercell’s Upcoming Multiplayer Game Launches Worldwide in May
The game now has been soft launched for both Android and iOS in several regions, with a worldwide release on May 29. The post Supercell’s Upcoming Multiplayer Game Launches Worldwide in May appeared first on Phandroid. Supercell R.....»»
Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell
The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»
Solar geoengineering to cool the planet: Is it worth the risks?
When I first wrote about geoengineering in 2012 , it was considered far-fetched at best, and crazy by most. But 12 years later, while there is still controversy and considerable resistance to deploying it, respectable scientists and institutions are.....»»
Researchers discover mechanism regulating bud dormancy release in tree peony
In perennial woody plants, bud endodormancy is crucial for survival under adverse environmental conditions in winter, such as low temperature (LT) and dehydration stress. To break bud dormancy is essential for the resumption of bud growth and floweri.....»»
Artificial intelligence helps scientists engineer plants to fight climate change
The Intergovernmental Panel on Climate Change (IPCC) has declared that removing carbon from the atmosphere is now essential to fighting climate change and limiting global temperature rise. To support these efforts, Salk Institute scientists are harne.....»»
Researchers show it"s possible to teach old magnetic cilia new tricks
Magnetic cilia—artificial hairs whose movement is powered by embedded magnetic particles—have been around for a while, and are of interest for applications in soft robotics, transporting objects and mixing liquids. However, existing magnetic cili.....»»
Leaf size and defensive traits found to modulate effects of soil fauna on litter decomposition
Leaf litter, as a multifunctional legacy of plants, plays an essential role in driving biogeochemical cycles, while providing important habitat and food resources for soil organisms. Litter traits and soil fauna play a crucial role in determining lit.....»»
eBook: Cloud security skills
Demonstrating a sound understanding of cloud security key principles and practices opens various professional opportunities. But first, you need the right mix of technical and soft skills to emerge as a leader. Inside this eBook: Why a career in clou.....»»
Using bacteriophage-derived lysin to target odor-causing bacteria in armpits
Body odor from the armpits comes from bacteria metabolizing sweat produced by the apocrine glands. These bacteria are native to our skin, but the odors produced differ among people. Generally, people use deodorants on their armpits, but perhaps there.....»»
Researchers create artificial cells that act like living cells
In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that look and act like cells f.....»»
Supercomputer simulation reveals new mechanism for membrane fusion
An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse......»»
Fossil frogs share their skincare secrets: Analysis of 45-million-year-old soft tissues
Paleontologists at University College Cork (UCC), Ireland, have solved a hundred-year-old mystery of how some fossil frogs preserve their fleshy parts—it's all down to their skin......»»
Researchers uncover natural variation in wild emmer wheat for broad-spectrum disease resistance
Bread wheat is one of the most important staple crops for millions of people and is apparently the largest cultivated and traded cereal worldwide. Bread wheat is a hexaploid species with three subgenomes (2n = 6x = 42, AABBDD) that has undergone two.....»»
Researchers report on mechanisms of gene regulatory divergence between species
Closely related animal species can look physically different, but you might be surprised to learn that those differences can result not only from DNA sequence changes that alter proteins' structure or function, but also because changes in the DNA aff.....»»
Bacteria for climate-neutral chemicals of the future
Researchers at ETH Zurich have engineered bacteria in the laboratory to efficiently use methanol. The metabolism of these bacteria can now be tapped into to produce valuable products currently made by the chemical industry from fossil fuels......»»