Suffering from psoriasis? Blame this trio of proteins
About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies -- and.....»»
Decoding the molecular networks of early human development
New international research shines a light on the role of transcription factors during early embryonic development. Transcription factors are proteins that are critical for gene regulation. The study unveiled more than 1,000 protein–protein interact.....»»
Manipulating host defenses: Unveiling the role of a powdery mildew effector in grapevine infection
Powdery mildew, caused by Erysiphe necator, is a significant threat to grapevine health, utilizing secreted effector proteins (CSEPs) to suppress plant defenses. Despite knowledge of plant immune mechanisms, the specific roles of E. necator's CSEPs i.....»»
Trio wins $700K Vesuvius Challenge grand prize for deciphering ancient scroll
The 2024 Challenge has also been announced, with a $100,000 grand prize. Enlarge / Text from one of the Herculaneum scrolls has been deciphered. Roughly 95 percent of the scroll remains to be read. (credit: Vesuvius Challenge).....»»
Preclinical study uncovers two proteins" crucial role in causing cancer cell growth
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. The study is published i.....»»
Nose picking likely ‘partially’ to blame for Alzheimer’s disease: scientists
Nose picking likely ‘partially’ to blame for Alzheimer’s disease: scientists.....»»
Researchers use supercomputer to determine whether "molecules of life" can be formed naturally in right conditions
Basic biology textbooks will tell you that all life on Earth is built from four types of molecules: proteins, carbohydrates, lipids, and nucleic acids. And each group is vital for every living organism......»»
Scientists successfully simulate protein complex that initiates fertilization
Researchers at ETH Zurich recently developed highly realistic simulations of the proteins on sperm and egg cells coupling together before they fuse. These findings enabled the research team to solve several mysteries of fertilization at once, which c.....»»
Researchers develop method to map interactions of specific RNA regions in live cells
The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct intera.....»»
New research brings order to disordered proteins
Protein molecules lie at the heart of biology. Our typical understanding of proteins states that each type of protein has a specific three-dimensional shape that enables it to perform its function. This dogma is challenged by intrinsically disordered.....»»
Narcissistic CEOs are bad for share value but good for company inertia, says study
Narcissistic leaders are bad for share value, unless they are seen to stimulate innovation and growth at companies suffering from corporate inertia, according to research that analyzed how CEO narcissism affects stock recommendations from securities.....»»
Parrots found to use "beakiation" to traverse small perches
A trio of osteopathic researchers at the New York Institute of Technology College of Osteopathic Medicine has found that one species of parrot uses its beak in a novel way to traverse small perches. In their project, reported in the journal Royal Soc.....»»
Computer-designed proteins allow for tunable hydrogels that can form both inside and outside of cells
When researchers want to study how COVID makes us sick, or what diseases such as Alzheimer's do to the body, one approach is to look at what's happening inside individual cells. Researchers sometimes grow the cells in a 3D scaffold called a "hydrogel.....»»
Team develops a non-allergenic wheat protein for growing better cultivated meat
As the world's population increases, cultivated or lab-grown meat—animal muscle and fat cells grown in laboratory conditions—has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to g.....»»
New AI model designs proteins to deliver gene therapy
Researchers at the University of Toronto have used an artificial intelligence framework to redesign a crucial protein involved in the delivery of gene therapy......»»
Future Apple Vision Pro may look out for strain in the user"s body
Apple is researching how to make the Apple Vision Pro see if users are sitting properly, and moreover to not blame the headset if wearing it puts a strain on their neck muscles.Apple Vision Pro could monitor neck strain despite not having any neck mu.....»»
New simulation tool advances molecular modeling of biomolecular condensates
A University of Massachusetts Amherst team has made a major advance toward modeling and understanding how intrinsically disordered proteins (IDPs) undergo spontaneous phase separation, an important mechanism of subcellular organization that underlies.....»»
Future Apple Vision Pro may look out strain in the user"s body
Apple is researching how to make the Apple Vision Pro see if users are sitting properly, and moreover to not blame the headset if wearing it puts a strain on their neck muscles.Apple Vision Pro could monitor neck strain despite not having any neck mu.....»»
New method for incorporating structurally unusual amino acids into proteins
A team of biochemists at the Medical Research Council Laboratory of Molecular Biology at Cambridge has developed a new method to incorporate structurally unusual amino acids into proteins by using bacteria. The method is described in the journal Natu.....»»
Russia Piracy Takedowns Up By 100%, “Western Rightsholders to Blame”
Russian telecoms watchdog Roskomnadzor is reporting a huge increase in the amount of infringing content it either blocked or deleted in 2023. The finger of blame for the 100%+ uplift over figures reported in 2022 can be found pointing towards Western.....»»
Fingerprinting biomolecules with the help of sound
A team of researchers from the Institute for Optoelectronic Systems and Microtechnology at Universidad Politécnica de Madrid (UPM) has designed a biosensor capable of identifying proteins and peptides in quantities as low as a single monolayer. For.....»»