Suffering from psoriasis? Blame this trio of proteins
About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies -- and.....»»
Heat to blame for space pebble demise
The dust of comets fills the space between the planets, collectively called the zodiacal cloud. Still, severe breakdown has reduced that dust in size so much that it now scatters sunlight efficiently, causing the faint glow in the night sky known as.....»»
Decoding the plant world"s complex biochemical communication networks
A Purdue University-led research team has begun translating the complex molecular language of petunias. Their grammar and vocabulary are well hidden, however, within the countless proteins and other compounds that fill floral cells......»»
High speed protein movies to aid drug design
Researchers from the University of Southampton have developed technology to help scientists observe proteins in motion. Understanding how proteins move will allow novel drugs to be designed......»»
Research challenges "universal mechanism" concept, aiming to understand specific protein interactions
Heat shock proteins (HSPs) are the chaperones of cellular stress response because they help guide the folding and unfolding of other proteins......»»
Research suggests natural electrical grid deep inside Earth enables many types of microbes to survive
To "breathe" in an environment without oxygen, bacteria in the ground beneath our feet depend upon a single family of proteins to transfer excess electrons (produced during the "burning" of nutrients) to electric hairs called nanowires projecting fro.....»»
Researchers explore how beluga whale melon changes shape during social interaction
A trio of animal science researchers at the University of Rhode Island, in the U.S., has identified five major shapes displayed by the beluga whale melon. For their study published in the journal Animal Cognition, Justin Richard, Isabelle Pellegrini,.....»»
In vivo production of CAR-T cells using virus-mimetic fusogenic nanovesicles
Chimeric antigen receptors (CARs) are synthesized membrane proteins that enable lymphocytes to recognize and respond to the specific antigens of target cells. Despite the impressive efficacy of CAR-T cell therapy in treating B-cell lymphoma or leukem.....»»
Shrimp waste revolution: Unlocking potent antioxidants for health and sustainability
Shrimp are renowned for their high nutritional value, offering a rich source of proteins, amino acids, omega-3 fatty acids, minerals, and vitamins, as well as chitin and carotenoids. The increasing consumption of shrimp has led to a significant rise.....»»
Ancient scrolls are being "read" by machine learning—with human knowledge to detect language and make sense of them
A groundbreaking announcement for the recovery of lost ancient literature was recently made. Using a non-invasive method that harnesses machine learning, an international trio of scholars retrieved 15 columns of ancient Greek text from within a carbo.....»»
New computational strategy boosts the ability of drug designers to target proteins inside the membrane
Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently.....»»
A simple and robust experimental process for protein engineering
A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study by University of Michigan researchers......»»
Image-scraping Midjourney bans rival AI firm for scraping images
Midjourney pins blame for 24-hour outage on "bot-net like" activity from Stability AI employee. Enlarge / A burglar with a flashlight and papers in a business office—exactly like scraping files from Discord. (credit: Getty Imag.....»»
Scientists develop deep learning method to design bilin-binding proteins
David Baker's group at the University of Washington, Seattle, U.S., have developed a novel deep learning method, RoseTTAFold All-Atom (RFAA), for prediction and design of complexes of proteins, small molecules, and nucleic acids. Subsequently, they d.....»»
Monarch caterpillar found to switch from avoiding milkweed-toxin-rich latex to eating it as they age
A trio of German entomologists has found that young monarch caterpillars switch from avoiding milkweed-toxin-rich latex to eating it as they get older. Their paper is published in the journal Proceedings of the Royal Society B......»»
How cells manage their mRNA stockpile and its output
In a typical cell, genes encoded in DNA are used to make messenger RNA (mRNA), which is used to make proteins, and this process of gene expression keeps the cell running. Gene expression is regulated in each cell such that specific genes are turned o.....»»
Research team develops new technique to release and study individual proteins in cells
A research team led by biochemist Professor Helge Ewers from Freie Universität Berlin has developed a new technique for the light-mediated release and investigation of proteins in live cells. The technique makes use of a laser pulse to control the r.....»»
Why do we blame the victim?
In an age of GoFundMe campaigns, it's easier than ever to help family, friends and even strangers in times of need. It's also easy to look the other way. "Most people see themselves as cooperative and generous, but there's a cost to helping people wh.....»»
Meet NASA’s trio of mini moon rovers set to launch next year
NASA introduces a trio of mini rovers which will work together as a team to map the lunar surface, testing out the possibilities of using rovers in groups......»»
Scientists use a new type of nanoparticle that can both deliver vaccines and act as an adjuvant
Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins. These vaccines often include other molecules called adjuvants, which help to boost the immune system's response to the protein......»»
Studying the relationships among cancer-promoting proteins
Researchers from the Bhogaraju Group at EMBL Grenoble have gained new insights into how a cancer-relevant family of proteins bind their targets. The results of the study, published in The EMBO Journal, could potentially help in the development of dru.....»»