New computational strategy boosts the ability of drug designers to target proteins inside the membrane
Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently.....»»
Bee body mass, pathogens and local climate influence heat tolerance
How well bees tolerate temperature extremes could determine their ability to persist in a changing climate. But heat tolerance varies between and within populations, so a research team led by Penn State entomologists examined bee physical traits—su.....»»
Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins
A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. Th.....»»
Synthetic chemistry approach yields new compounds with potential biomedical applications
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability to modulate protein-protein.....»»
Simulated chemistry: New AI platform designs tomorrow"s cancer drugs
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen t.....»»
A global plastic treaty will only work if it caps production, modeling shows
An international agreement to end plastic pollution is due to be sealed this year in Busan, South Korea. At the penultimate round of negotiations, held in Ottawa, Canada, Rwanda and Peru proposed a target to cut the weight of primary plastics produce.....»»
Researchers develop new AI tool for fast and precise tissue analysis to support drug discovery and diagnostics
A team of scientists from A*STAR's Genome Institute of Singapore (GIS) and Bioinformatics Institute (BII) has developed a new AI software tool called "BANKSY" that automatically recognizes the cell types present in a tissue, such as muscle cells, ner.....»»
Morgan Stanley hikes Apple stock target after unexpectedly positive earnings
Despite a recent Apple stock price target cut bank Morgan Stanley is amongst Apple's biggest bulls — and it has proven that by nudging the company's price target up to $216.An Apple Store signMorgan Stanley was oddly bullish about Apple even as it.....»»
An eraseable "Let Loose" event logo teases a new Apple Pencil feature
Apple has changed its "Let Loose" event logo to include the ability to erase it by dragging a mouse — or presumably a forthcoming Apple Pencil — across it.Users can now "erase" the Apple event logoThe "Let Loose" event already had a series of art.....»»
First steps toward a whole-body map of molecular responses to exercise
Research definitively confirms that muscle-moving, calorie-burning activity slows the advance of disease, improves cognitive function, boosts the immune system, and reduces rates of mortality from all causes......»»
Physicists pioneer new quantum sensing platform
Quantum sensors detect the smallest of environmental changes—for example, an atom reacting to a magnetic field. As these sensors "read" the unique behaviors of subatomic particles, they also dramatically improve scientists' ability to measure and d.....»»
Vortex fluidic device can speed artificial liposome production to aid drug functionality
The expansion of clean chemistry applications for the vortex fluidic device (VFD)—invented by Flinders University's Professor Colin Raston—continues with the successful rapid and simplified production of artificial liposomes that could help trans.....»»
Novel chemical tool for understanding membrane remodeling in the cell
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell......»»
Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Positive school climate boosts high school grades, study finds
A study led by a UC Riverside graduate student has found that Latino high school students achieve higher grades when they perceive a more positive school climate and when they have a stronger sense of self-esteem......»»
FortiGate 200G series boosts campus connectivity for Wi-Fi 7
Fortinet announced a new next-generation firewall (NGFW) appliance with the security and networking performance needed to serve as the backbone of the modern campus. Built on the Fortinet operating system, FortiOS, and the latest, fifth-generation Fo.....»»
BlackBerry CylanceMDR improves cybersecurity defensive strategy
BlackBerry introduced the new and expanded CylanceMDR, offering comprehensive Managed Detection & Response (MDR) protection powered by the Cylance AI platform and augmented with award-winning security operations center analysts for 24×7 threat c.....»»
Most companies changed their cybersecurity strategy in the past year
Businesses worldwide have faced a rate of change in the threat environment evidenced by 95% of companies reporting cybersecurity strategy adjustments within just the past year, according to LogRhythm. Strategic shifts within organizations At the hear.....»»
Coastal hurricanes around the world are intensifying faster, new study finds
Hurricanes are among the world's most destructive natural hazards. Their ability to cause damage is shaped by their environment; conditions like warm ocean waters, guiding winds, and atmospheric moisture can all dictate storm strength......»»
AT&T wants you to pay an extra $7 per month for ‘Turbo’ 5G speeds
AT&T thinks people are willing to pay $7 extra per month for what it claims is “enhanced data connectivity for real-time responsiveness.” This new AT&T “Turbo” option is rolling out now, and the carrier says it “boosts all the high-speed an.....»»
International team cracks genomic code for earliest forms of terrestrial plant life
Plant life first emerged on land about 550 million years ago, and an international research team co-led by University of Nebraska–Lincoln computational biologist Yanbin Yin has cracked the genomic code of its humble beginnings, which made possible.....»»