Stem cells reveal underpinnings of rare immune disease
A new stem cell study by KAUST researchers helps to explain a rare genetic disease called Wiskott-Aldrich syndrome (WAS), yielding molecular clues that could lead to new treatments for a devastating immune deficiency disorder. The results are publish.....»»
An adjuvant made in yeast could lower vaccine cost and boost availability
Vaccines save lives, as proven during the recent pandemic, but one component of most vaccines—including the Novavax COVID-19 vaccine—goes unheralded: a molecule or other compound that primes the immune system to mount a more robust defense agains.....»»
Researchers discover new function of oncoproteins
Researchers at the University of Würzburg have discovered a new function of the oncoprotein MYCN: It not only helps cancer cells to grow stronger, but also makes them more resistant to drugs. The study is published in Molecular Cell......»»
Discovery of ancient Glaswegian shrimp fossil reveals new species
A short but robust little shrimp may have died out over 330 million years ago during the Carboniferous period, but the rare Scottish shellfish has been revitalized as a new species to science and as a Glaswegian......»»
New technology changes how proteins in individual cells are studied
Researchers from Karolinska Institutet, together with Pixelgen Technologies, have developed and applied a technique that makes it possible to map proteins in individual cells in a completely new way. Not only is it now possible to measure the amount.....»»
Study pinpoints cellular response to pressure in sea star embryos
An international team of scientists has discovered a new cellular mechanism that explains how cells can adapt to pressure changes during tissue growth by packing themselves into a unique shape......»»
MITRE breach details reveal attackers’ successes and failures
MITRE has shared a timeline of the recent breach if fell victim to and has confirmed that it began earlier than previously thought: on December 31, 2023. On that day, the attackers deployed a web shell on an external-facing Ivanti Connect Secure VPN.....»»
Bsal and beyond: Task force helps stave off amphibian disease threat
Amphibians—like frogs and salamanders—are the most imperiled group of animal species in the world; infectious diseases are among the greatest threats to their existence. After a decade of research, a scientific task force is poised to stave off t.....»»
Researchers reveal how molecular roadblocks slow the breakdown of cellulose for biofuels
Cellulose, which helps give plant cell walls their rigid structure, holds promise as a renewable raw material for biofuels—if researchers can accelerate the production process. Compared to the breakdown of other biofuel materials like corn, breakin.....»»
Apple doubles down on AI virtual musicians, adds intelligent stem splitting, more in new Logic Pro for iPad and Mac
Today at Apple’s Let Loose event, we got our first look at its new M4 chip and the new iPad Pros it powers, the next-generation iPad Air, and the new Apple Pencil Pro, but it wasn’t all hardware. Apple also briefly touched on the latest editions.....»»
Geologists reveal mysterious and diverse volcanism in lunar Apollo Basin, Chang"e-6 landing site
The far side of the moon is a mysterious place that is never visible from the Earth. The most remarkable feature of the moon is its asymmetry between the lunar near side and far side in composition, crust thickness, and mare volcanism. Scientists hav.....»»
New research confirms that Beethoven had lead poisoning—but it didn"t kill him
To this day, no one knows for certain what caused the liver and kidney disease that led to Ludwig van Beethoven's untimely death. However, a new letter to the editor in the journal Clinical Chemistry rules out one popular theory, showing that the com.....»»
Discovery of structural specialization in myriapod ovaries
Elaborate observations reveal the structural specialization within an epithelial layer covering oocytes in the Japanese pill-millipede, Hyleoglomeris japonica, considered absent in Myriapoda. Comparing this result with previous descriptions suggested.....»»
Study reveals differences in DNA folding between neurons and other brain cells, links them to cell functions
Researchers from Skoltech and their colleagues have investigated nerve cell regulation. Mounting knowledge of regulation mechanisms could enable a better understanding of how the healthy brain operates and what goes wrong in developmental and oncolog.....»»
Study sheds light on cancer cell "tug-of-war"
Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is a.....»»
Decoding development: mRNA"s role in embryo formation
A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights into how pluripotent cells a.....»»
Materials scientists reveal pathway for designing optical materials with specialized properties
While we usually think of disorder as a bad thing, a team of materials science researchers led by Rohan Mishra, from Washington University in St. Louis, and Jayakanth Ravichandran, from the University of Southern California, have revealed that—when.....»»
Free-forming organelles help plants adapt to climate change
Plants' ability to sense light and temperature, and their ability to adapt to climate change, hinges on free-forming structures in their cells whose function was, until now, a mystery......»»
Seeing is believing: Observation of migrasomes
Migrasomes, novel organelles first reported by Professor Li Yu' s team in 2015, are vesicular structures with diameters ranging from 0.5 to 3 micrometers that form on the retraction fibers at the rear of migrating cells. These structures contain vari.....»»
Designing a novel substrate for myogenic differentiation from induced pluripotent stem cells
Since their discovery, researchers have repeatedly demonstrated the potential medical applications of differentiated cells and tissues generated from induced pluripotent stem (iPS) cells. However, a significant hurdle to real-world medical applicatio.....»»
Nanoparticle researchers develop microfluidic platform for better delivery of gene therapy for lung disease
Drug delivery researchers at Oregon State University have developed a device with the potential to improve gene therapy for patients with inherited lung diseases such as cystic fibrosis......»»