Secondary infections inflame the brain, worsening cognition in Alzheimer"s disease
New research into Alzheimer's disease (AD) suggests that secondary infections and new inflammatory events amplify the brain's immune response and affect memory in mice and in humans -- even when these secondary events occur outside the brain......»»
Crispr-Enhanced Viruses Are Being Deployed Against UTIs
With antibiotics losing their effectiveness, one company is turning to gene editing and bacteriophages—viruses that infect bacteria—to combat infections......»»
Silver nanoparticles and a new sensing method can fight back against antibiotic-resistant biofilms
From safeguarding our food supply to preventing hospital infections, the battle against antibiotic-resistant bacteria is a growing challenge. Some bacteria can form biofilms, thick aggregates of millions of individual cells surrounded by protective m.....»»
Scientists learn how to drug wily class of disease-causing enzymes
UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable.".....»»
Strawberry disease could threaten Hampton Roads" spring harvest
In a few weeks, strawberry growers in southeast Virginia will plant their crop to be harvested in May. But many are concerned about a disease that could drastically reduce next year's yield......»»
Studying fungi"s "weak link" to fight global rise in deadly fungal infections
A group of scientists at the Department of Energy's Oak Ridge National Laboratory have conducted neutron scattering research to reveal key information about fungus cell membranes that could aid in developing new antifungal treatments......»»
How context-specific factors control gene activity
Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene regulation; essentially how and when genes are turned.....»»
The Mosquito-Borne Disease ‘Triple E’ Is Spreading in the US as Temperatures Rise
Eastern equine encephalitis, which has a high mortality rate, is becoming more common in North America as climate changes expands the habitats of insects......»»
Why Polio Has Reemerged in Gaza
After a quarter of a century, the disease has returned to Gaza, prompting a campaign to immunize all of the territory's children against the virus......»»
This could increase your risk of Alzheimer’s disease more than anything: study
This could increase your risk of Alzheimer’s disease more than anything: study.....»»
Solving the side effect problem of siRNA drugs for genetic disease treatment
Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence genes other than the target ones, causing side eff.....»»
Neolithic bones reveal isolated Yersinia pestis infections, not pandemics
Since the catastrophic pandemics of the Middle Ages, one disease has almost proverbially symbolized contagion and death: the plague. It is now known that the plague bacterium Yersinia pestis has been present in Central and Northern Europe for more th.....»»
Phage editing technology could lead to alternative treatments for antibiotic-resistant bacteria
As antibiotic resistance becomes an increasingly serious threat to our health, the scientific and medical communities are searching for new medicines to fight infections. Researchers at Gladstone Institutes have just moved closer to that goal with a.....»»
Q&A: How single-cell and spatial proteomics reveal proteins" nuanced roles in health and disease
When Steve Carr, senior director of the Proteomics Platform at the Broad Institute of MIT and Harvard, began working in proteomics, the field was able to detect only the most abundant proteins in a given sample. In recent years, increasingly sensitiv.....»»
New mRNA and gene editing tools offer hope for dengue virus treatment
Dengue virus, a painful and sometimes fatal mosquito-borne infection well known in tropical countries, is surging rapidly across the planet. Now, 4 billion people live in places at risk for the disease, like the southeastern United States, which does.....»»
Algorithm maps protein degradation patterns to improve infection diagnosis and treatment
Peptides are small fragments of proteins, mainly found in the skin and mucous membranes. Some peptides act as a barrier, protecting the body against infections by fighting off microorganisms like bacteria, viruses, and other pathogens, while others p.....»»
Researchers develop molecular biosensors that only light up upon binding to their targets
Biosensors—devices that use biological molecules to detect the presence of a target substance—have enormous potential for detecting disease biomarkers, molecules-in-action in diverse biological processes, or toxins and other harmful substances in.....»»
Moderna mRNA mpox vaccine shows promise in animal study
An experimental Moderna mRNA vaccine for mpox has demonstrated greater effectiveness than current shots in reducing disease symptoms and duration, according to an animal study published in the journal Cell on Wednesday......»»
Diagnosing oak wilt with the naked eye
University of Minnesota researchers developed a groundbreaking method for the rapid and accurate detection of oak wilt, a devastating disease threatening oak trees across North America. The disease is widespread in east-central and southeast Minnesot.....»»
Preventing cell damage: Working principle of proton-activated chloride channels revealed
A research team led by Prof. Seo Byeong-Chang of the Department of Brain Sciences at DGIST has made the world's first discovery of how proton-activated chloride (PAC) channels—which play an important role in protecting cells in our bodies—work. P.....»»
Denmark reports cases of bluetongue disease that can be fatal to sheep but is harmless to humans
Denmark reported Tuesday cases of bluetongue in the country's east, a non-contagious, insect-borne viral disease that is harmless to humans but can be fatal for so-called ruminant animals—mainly sheep but also cows and goats......»»