Repurposed protease controls important signaling molecule-activating protein
Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease. The rapid release of at least 80 signaling molecules, including tumor necrosis factor and epidermal growth factor, is con.....»»
New synthetic receptor expands cellular control options, including immune response and neurological signaling
A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists is to control that process, making cells respond how they want to what they want......»»
New pathway found for regulating zinc in E. coli
Cornell researchers have discovered a pathway by which E. coli regulates all-important zinc levels, an insight that could advance the understanding of metal regulation in bacteria generally and lead to antibacterial applications such as in medical in.....»»
AI model enables reliable and accurate protein-ligand complex prediction
Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the heart of many cellular processes, from enzyme catalysis to signal transduction. The foundational knowledge of protein–li.....»»
Assessing the sustainability of the Pacific walrus population over the next 75 years
The Pacific walrus, a critically important resource for Alaska and Chukotka Native communities, is subject to rapid habitat loss associated with climate change and increasing human activity in the Arctic. New research published in The Journal of Wild.....»»
Discovery of molecular switch explains how bacteria control their protein biosynthesis through cell metabolism
Protein biosynthesis—the process whereby cells produce protein molecules, which are essential for life and growth—is a highly complex and strictly regulated affair. An interdisciplinary team led by LMU biologist PD Dr. Jürgen Lassak has now disc.....»»
Decoding protein interactions to better understand how mutations contribute to disease
Investigating how proteins interact is key to understanding how cells work and communicate. In a new study published in Nature Communications, FMI researchers have provided key insights into how protein interactions are governed and how mutations inf.....»»
Enzyme study sheds light on the molecular mechanism behind "sleepiness"
Recent research has observed that chemical modifications called phosphorylation of proteins in brain neurons dynamically regulate sleep and wakefulness. But the protein kinases that suppress sleep and the dephosphorylation enzymes that control sleep.....»»
Researchers find a way to make 3D printed pea gels hold their shape better, strengthening potential for use as food
Using plasma, the stuff of the universe, University of Alberta researchers have improved the 3D printability of a valuable plant protein for use in food. The study is published in the journal Food Bioscience......»»
Physicists take a step closer to controlling single-molecule chemical reactions
Controlling matter at the atomic level has taken a major step forward, thanks to nanotechnology research by an international team of scientists led by physicists at the University of Bath......»»
Study discovers a nano-switch mechanism controlled by a single hydrogen atom in all living organisms
A group of researchers in Japan has revealed, for the first time, a mechanism for controlling the potential of an electron carrier protein in the redox reaction that all organisms need to obtain energy. The study was published in the online edition o.....»»
Peroxisomal protein boosts plant immunity to thrive under environmental stress
Salicylic acid is vital for protecting plants from pathogens, but its synthesis remains unclear. A team of Shinshu University researchers has discovered that the protein HSR201 is key to its production. They found that HSR201 localizes to specific or.....»»
Resurrecting an ancestral protein as a novel tool to study RNA biology
By deducing the possible ancient forms of a bacterial enzyme, OIST scientists have resurrected one of its ancestral versions, with a comparably higher ability to chemically modify RNA......»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
Scientists develop self-sustained protein transport and tissue assembly in artificial cells
In a new Nature Communications study, scientists have developed a novel method for artificial cells to interact with their external environment without the need for complex modification processes......»»
Canada must turn its impressive biodiversity protection goals into real actions
With biodiversity declining at unprecedented rates worldwide, Canada stands at an important crossroads......»»
Landmark study reveals stark failure to halt Murray-Darling River decline
Some A$13 billion in taxpayer dollars and 30 years of policy reform have failed to arrest the devastating decline in the health of Australia's most important river system, the Murray-Darling Basin, new research shows......»»
New approach uses observed local supervoid to give expansion of the universe an extra push and solve the Hubble tension
Astronomers have known for a century that the universe is expanding. We can now trace this expansion over much of its almost 14 billion year history, with important constraints going back to just one second after the Big Bang! The expansion rate toda.....»»
Novel quantum computing algorithm enhances single-cell analysis
A new quantum algorithm developed by University of Georgia statisticians addresses one of the most complex challenges in single-cell analysis, signaling significant impact in both the fields of computational biology and quantum computing......»»
Modernizing incident response in the AI era
In this Help Net Security video, Gourav Nagar, Director of Information Security at Bill, discusses modernizing incident response in the era of AI and the cloud: Why this issue is important for organizations looking to stay ahead of rapidly evolving c.....»»
Scientists reveal structural link for initiation of protein synthesis in bacteria
Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has been a visual mys.....»»