Protein remodels intracellular membrane to help Legionella bacteria survive in host cells
Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires' disease to set up house in the cells of humans and other hosts. The findings, published in Science, could offer insights into how other bact.....»»
Research provides new insights into role of mechanical forces in gene expression
The genome inside each of our cells is modeled by tension and torsion—due in part to the activity of proteins that compact, loop, wrap and untwist DNA—but scientists know little about how those forces affect the transcription of genes......»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
DNA nanotechnology unravels complex protein interactions to inform cancer diagnostics
A team of researchers from NUS Institute for Health Innovation & Technology (iHealthtech), led by Associate Professor Shao Huilin and Associate Professor Brian Lim, has developed a first-of-its-kind technology to map out diverse protein interactions.....»»
Protein study reveals how the tiny shrew achieves a resting heart rate of 1,020 beats per minute
The shrew's resting heart rate can reach up to 17 beats per second, equivalent to about 1,020 beats per minute. In comparison, the average human resting heart rate is around 60 to 100 beats per minute, making the shrew's resting heart rate approximat.....»»
Advances in processable natural biopolymers: Cellulose, chitosan, eggshell membrane and silk fibroin
A study in Science Bulletin explores the recent advancements in the development of processable natural biopolymers and their myriad applications......»»
Hunting down giant viruses that attack tiny algae
They were said to come from outer space, and there were even claims that they were actually bacteria and that they undermined the very definition of viruses. Giant viruses, nicknamed "giruses," contain enormous quantities of genetic material—up to.....»»
Webb detects fast outflow in the host galaxy of a luminous quasar
An international team of astronomers has employed the James Webb Space Telescope (JWST) to perform spectroscopic observations of a luminous quasar known as J1007+2115. They detected a fast outflow originating from the quasar's host galaxy. The findin.....»»
Your cells are dying. All the time.
Your cells are dying. All the time......»»
Fireworks forecast if comet survives risky sun flypast
A comet is expected to risk having its tail clipped on Friday by flying perilously close to the sun, promising fireworks next month should it survive the fraught flypast......»»
Trimer complex TaNF-Y balances grain yield and quality in wheat: Study
Breeding efforts have focused intensively on improving grain yield and quality in wheat (Triticum aestivum L.). Content and composition of grain starch and seed storage protein (SSP) are two critical factors that determine grain yield and quality. St.....»»
Exploring the role of hydrogen sulfide in the expression of iron uptake genes in E. coli
Antibiotic resistance and oxidative stress response are important biological mechanisms that help bacteria thrive, especially pathogenic bacteria like Escherichia coli. Hydrogen sulfide (H2S), a chemical messenger molecule, regulates several intracel.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
Elucidating the mechanism of cell division during plant self-healing
When the stem of a plant is injured, the surrounding cells proliferate to repair and fuse the damaged tissue, eventually restoring function. This self-healing property is utilized in grafting techniques to propagate fruit and vegetable plants......»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Presence of bacteria in soil makes flowers more attractive to pollinators, study shows
Bacteria that live in soil and help roots fix nitrogen can boost certain plants' capacity to reproduce, according to an article published in the American Journal of Botany describing a study of this mechanism in Chamaecrista latistipula, a legume bel.....»»
Building better bone grafts: Nanofibrous scaffolds to activate two main collagen receptors in bone cells
Each year, about 2.2 million bone-grafting procedures are performed worldwide, the gold standard of care being autografting, which uses the patient's own bone for tooth implantation and to repair and reconstruct parts of the mouth, face and skull......»»
Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epi.....»»
Scientists develop method to control timing of synthetic DNA droplet division
Many cellular functions in the human body are controlled by biological droplets called liquid-liquid phase separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside living cells but are not enclosed by membranes like.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»