Protein engineers navigate toward more targeted therapeutics
More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate responses. Drugs that eit.....»»
Researcher creates algorithm to aid in discovery of new medicines
Ph.D. candidate Jeroen Methorst has developed a computer system that helps researchers find the protein they need to create new medicines. "Our whole group is now using this program," says Methorst. He will defend his Ph.D. thesis on April 2......»»
Apple users targeted by sophisticated phishing attack to reset their ID password
There are many known phishing attacks that target users of Apple devices to gain access to their Apple ID. However, a new “elaborate” attack uses a bug in the Apple ID password reset feature with “push bombing” or “MFA fatigue” techniques.....»»
How self-driving cars can talk to themselves to navigate the world
Autonomous vehicle companies are employing large language models, a deep learning tool to predict and generate language that can be used to reason through novel situations......»»
Artificial reef designed by engineers could protect marine life, reduce storm damage
The beautiful, gnarled, nooked-and-crannied reefs that surround tropical islands serve as a marine refuge and natural buffer against stormy seas. But as the effects of climate change bleach and break down coral reefs around the world, and extreme wea.....»»
Apple"s removable battery standard could change device charging forever
Apple's engineers are researching how to best make a series of standardized enclosures that would allow users to routinely swap batteries between higher-powered devices like an iMac, and lower powered ones like keyboards or other peripherals.Multiple.....»»
New study shows treating work like a game drives results
A study from West Virginia University engineers demonstrates that people's completion of monotonous assembly tasks improves when doing those tasks involves playing a game......»»
Justice Department indicts 7 accused in 14-year hack campaign by Chinese gov
Hacks allegedly targeted US officials and politicians, their spouses, and dozens of companies. Enlarge (credit: peterschreiber.media | Getty Images) The US Justice Department on Monday unsealed an indictment charging sev.....»»
Scammers steal millions from FTX, BlockFi claimants
Customers of bankrupt crypto platform BlockFi have been targeted with a very convincing phishing email impersonating the platform, asking them to connect their wallet to complete the withdrawal of remaining funds. Judging by this Reddit thread, many.....»»
Rectifying AI"s usage in the quest for thermoelectric materials
A team of researchers has used AI to identify a thermoelectric material with favorable values. The group was able to navigate AI's conventional pitfalls and big data challenges, offering a prime example of how AI can revolutionize materials science......»»
Scientists discover how a motor protein helps cells move
Scientists have used the latest advances in microscopy to characterize how a motor protein helps cells crawl, according to a study published in the Journal of Cell Biology......»»
Scams are becoming more convincing and costly
Scams directly targeting consumers continue to increase in both complexity and volume, according to Visa. Consumers are increasingly targeted by scammers, who rely on heightened emotions to create fraud opportunities. While the number of individual s.....»»
Researchers devise new way to find proteins for targeted treatment of disease
Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins—a new but largely unrealized approach to the treatment of disease......»»
US organizations targeted with emails delivering NetSupport RAT
Employees at US-based organizations are being targeted with emails delivering NetSupport RAT malware via “nuanced” exploitation and by using an advanced detection evasion method. The malware campaign The campaign, dubbed PhantomBlu, takes.....»»
Apple looking inside China for AI providers to sidestep regulatory issues
Apple may need to navigate the business and regulatory waters in China with a local AI provider, and Baidu may have the technology it needs.A Siri icon superimposed on Apple ParkApple has a very large artificial intelligence division, that has been l.....»»
Messenger RNAs with multiple "tails" could lead to more effective therapeutics, say researchers
Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines. But mRNAs, which are genetic sequences that instruct the body to produce proteins, are also being devel.....»»
Apple’s green bubbles targeted by DOJ in lawsuit over iPhone “monopoly”
RCS and green bubbles in iPhone-to-Android texts play role in Apple/DOJ battle. Enlarge (credit: Getty Images | NurPhoto) The US Department of Justice is angry about green message bubbles. Announcing today's antitrust la.....»»
High speed protein movies to aid drug design
Researchers from the University of Southampton have developed technology to help scientists observe proteins in motion. Understanding how proteins move will allow novel drugs to be designed......»»
Research challenges "universal mechanism" concept, aiming to understand specific protein interactions
Heat shock proteins (HSPs) are the chaperones of cellular stress response because they help guide the folding and unfolding of other proteins......»»
Research reveals new starting points for the rapid and targeted development of future drugs
Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools for synthetic biology. By.....»»
Scientists elucidate the role of GlyT1 in anti-schizophrenia drugs
Schizophrenia is a highly disabling mental disorder, and numerous studies have shown that the hypofunction of the N-methyl-d-aspartate (NMDA) receptor is one of its pathogenic mechanisms. Glycine transporter 1 (GlyT1), a glycine transporter protein,.....»»