Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
Predicting river flow dynamics using stable isotopes for improved ecosystem health
An international science team has made significant strides in understanding river flow dynamics. The findings leverage isotope hydrology techniques such as measuring stable isotopes in water molecules to elucidate the contributions of various water s.....»»
New findings can help improve our understanding of winter weather in the St. Lawrence River Valley
A recent study at McGill University provides new insights into how winter storms develop in the St. Lawrence River Valley, findings that could potentially improve the accuracy of winter weather forecasts in the region......»»
Research provides new insights into role of mechanical forces in gene expression
The genome inside each of our cells is modeled by tension and torsion—due in part to the activity of proteins that compact, loop, wrap and untwist DNA—but scientists know little about how those forces affect the transcription of genes......»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
Understanding regional climate change is essential for guiding effective climate adaptation policy, study says
The effects of climate change are not distant future scenarios or confined to remote parts of the world—they are unfolding now, right in our own backyards. In 2023, extreme weather events impacted communities across every inhabited continent, causi.....»»
DNA nanotechnology unravels complex protein interactions to inform cancer diagnostics
A team of researchers from NUS Institute for Health Innovation & Technology (iHealthtech), led by Associate Professor Shao Huilin and Associate Professor Brian Lim, has developed a first-of-its-kind technology to map out diverse protein interactions.....»»
Protein study reveals how the tiny shrew achieves a resting heart rate of 1,020 beats per minute
The shrew's resting heart rate can reach up to 17 beats per second, equivalent to about 1,020 beats per minute. In comparison, the average human resting heart rate is around 60 to 100 beats per minute, making the shrew's resting heart rate approximat.....»»
Geologists discover mysterious subduction zone beneath Pacific, reshaping understanding of Earth"s interior
University of Maryland scientists uncovered evidence of an ancient seafloor that sank deep into Earth during the age of dinosaurs, challenging existing theories about Earth's interior structure. Located in the East Pacific Rise (a tectonic plate boun.....»»
Trimer complex TaNF-Y balances grain yield and quality in wheat: Study
Breeding efforts have focused intensively on improving grain yield and quality in wheat (Triticum aestivum L.). Content and composition of grain starch and seed storage protein (SSP) are two critical factors that determine grain yield and quality. St.....»»
How climate change affects deer—experts draw findings from 20 years of research
Temperature, rainfall, snow and extreme weather events are all factors linked to climate change that directly affect wildlife. Understanding the impact of these factors on the physiology, population dynamics and distribution of different deer species.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Marine dust identifies 1.5 million year Oldest Ice near South America
Earth's climate has experienced major shifts over its billions of years of history, including numerous periods where ice proliferated across the planet. Today, ice cores can be a valuable resource for understanding these periods of Earth's history as.....»»
New research could extend the lifetime of key carbon-capture materials
Researchers at Lawrence Livermore National Laboratory (LLNL), in collaboration with the Georgia Institute of Technology, have made a significant breakthrough in understanding the impact of carbon dioxide (CO2) on the stability of amine-functionalized.....»»
Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epi.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
How social structure influences the way people share money
People around the globe often depend on informal financial arrangements, borrowing and lending money through social networks. Understanding this sheds light on local economies and helps fight poverty......»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Chevy woos Equinox EV buyers with Erewhon juice giveaway
Chevy is giving bottles of an electric-blue protein drink to people who test-drive an Equinox EV at an Erewhon organic market in L.A......»»