Path to precision: Targeted cancer drugs go from table to trials to bedside
What started in a scientist's dining room is now in tissue-agnostic combo trials. Enlarge (credit: Aurich Lawson) In 1972, Janet Rowley sat at her dining room table and cut tiny chromosomes from photographs she had taken.....»»
Researchers call for recognition of tire particles as a distinct environmental threat
A new study led by an international team of scientists highlights tire particles (TPs) as the leading contributor to microplastics and calls for urgent, targeted research to address their unique environmental and health risks......»»
Metagenomic profiling method with enhanced precision uses fewer computing resources
Researchers at Carnegie Mellon University and the University of Toronto have developed a new k-mer sketching metagenomic profiler, called sylph, that allows scientists to analyze genomic data more quickly and precisely than other profilers......»»
Squishy microgels in granular biomaterials confine and direct cell behavior
A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State......»»
Simple model system can break down fibrils to investigate drugs for neurodegenerative diseases
The origin of many diseases such as Alzheimer's or Parkinson's can be found at the molecular level in our body, in other words, in proteins. In a healthy system, these proteins are responsible for numerous physiological functions......»»
Physicists achieve high-precision imaging of complex molecules using highly charged ions
A new study published in Physical Review Letters and led by researchers from the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) has demonstrated that a Coulomb explosion induced by highly charged ions is a unique tool for.....»»
Aerospace employees targeted with malicious “dream job” offers
It’s not just North Korean hackers who reach out to targets via LinkedIn: since at least September 2023, Iranian threat actor TA455 has been trying to compromise workers in the aerospace industry by impersonating job recruiters on the popular e.....»»
Most US book bans target children"s literature featuring diverse characters and authors of color
Book bans in U.S. schools and libraries during the 2021-22 school year disproportionately targeted children's books written by people of color—especially women of color—according to a peer-reviewed study we published. They also tended to feature.....»»
Virtual fruity fly model can simulate sensory navigation
All animals, large or small, have to move at an incredible precision to interact with the world. Understanding how the brain controls movement is a fundamental question in neuroscience. For larger animals, this is challenging because of the complexit.....»»
Trump tariffs will raise prices, but Apple has set the table to avoid the worst of it
Proposed tariffs under the Trump administration could trigger considerable price increases for consumer electronics in the United States, though Apple may be able to weather the storm.Apple CEO Tim Cook [left] with Donald Trump [right]During his firs.....»»
5 years ago, The Mandalorian made Star Wars fun again
Five years ago, The Mandalorian showed a new path forward for Star Wars. How did it so quickly lose its way?.....»»
Using CRISPR to decipher whether gene variants lead to cancer
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A patient's immune cells can be specifically reprogramm.....»»
Dehumanizing child-free women in film and TV gives misogyny a stage
"When are you giving us grandkids?" and "You'll change your mind," are familiar lines heard by child-free women around the table at family dinner......»»
Kuo: Apple to release its own smart home camera in 2026, with AI features
Apple analyst Ming-Chi Kuo reported today that Apple will enter the smart home camera market in 2026, with the company seemingly set to compete against third-party HomeKit cameras like the for the first time. The IP camera is targeted to hit annu.....»»
Laser spectroscopy study explores nuclear structure of fermium and nobelium isotopes
University of Liverpool researchers are part of an international research collaboration that has shed light on what happens at the extremes of neutron and proton numbers, in search of where the periodic table of chemical elements ends......»»
Industrial companies in Europe targeted with GuLoader
A recent spear-phishing campaign targeting industrial and engineering companies in Europe was aimed at saddling victims with the popular GuLoader downloader and, ultimately, a remote access trojan that would permit attackers to steal information from.....»»
A causal theory for studying the cause-and-effect relationships of genes paves the way for targeted treatments
By studying changes in gene expression, researchers learn how cells function at a molecular level, which could help them understand the development of certain diseases......»»
Assessing the efficacy of clinical drugs targeting SARS-CoV-2 main protease
Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the original wild-type strains to the highly transmissible omicron variant......»»
Gray squirrel control: Study shows promise for effective contraceptive delivery system
A study published in the journal Pest Management Science sheds light on the behavior of gray squirrels (Sciurus carolinensis) and explores methods for the targeted delivery of oral contraceptives to control their populations......»»
Ultrasensitive nanoscale sensors can identify lung cancer through exhaled isoprene
Exhaled breath contains chemical clues to what's going on inside the body, including diseases like lung cancer. And devising ways to sense these compounds could help doctors provide early diagnoses—and improve patients' prospects. In a study in ACS.....»»
Smog sickness: India"s capital struggles as pollution surges
The toxic smog season in India's capital has just begun, but those unable to escape cancer-causing poisonous fumes say the hazardous impact on health is already taking its toll......»»