Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Old drugs new tricks—novel approach shows "enormous potential" for rapid antibiotic discovery
An innovative project to re-purpose existing drugs for their potential as antibiotics has uncovered a highly promising candidate with a potent and unique way of killing drug resistant bacteria......»»
Ultrasound beam triggers "nanodroplets" to deliver drugs at exactly the right spot
Conventional drug delivery is often like cracking a nut with a sledgehammer. Whether the drug is swallowed, injected, inhaled, or absorbed through the skin, it ultimately diffuses to most parts of the body, including those where it isn't needed—or.....»»
New biocatalytic method eliminates cyanide in nitrile production
If the household cleaner emits a lemon-like odor, this may be due to a nitrile called citronellyl nitrile. These versatile chemical nitrile groups are also used in the manufacture of active pharmaceutical ingredients, superglue and chemical-resistant.....»»
Researchers report on effectiveness of violence against women campaigns during sports events
In a paper published in the journal Event Management, researchers have investigated the Gold Coast 2018 Commonwealth Games and its One Million Stars to End Violence (OMSTEV) campaign to see how effective such a campaign was when connected to a major.....»»
Tweets analyzed by scientists offer insight into effective hurricane risk messaging
Forecasters can use images in social media to better communicate weather related hazards of hurricanes, according to a pair of new studies. The findings are published in the journals Natural Hazards Review and Weather, Climate, and Society.....»»
Collaborative approaches improve materials informatics workforce training
A wide range of innovative products, from biomedical implants to aerospace composites, come from research in materials informatics (MI)—the combination of machine learning, artificial intelligence and computational methodologies with materials scie.....»»
Investigating nematode-microbe interactions in lab-simulated decomposed beetle environments
Beneath the surface, bacterivorous nematodes are key players in the nutrient cycle, consuming bacteria that decompose organic matter. Traditionally, these nematodes are studied in laboratory environments where isolated bacterial strains are used to m.....»»
To streamline drug discovery, team develops algorithmic framework to identify optimal molecular candidates
The use of AI to streamline drug discovery is exploding. Researchers are deploying machine-learning models to help them identify molecules, among billions of options, that might have the properties they are seeking to develop new medicines......»»
Ultraviolet-absorbing film shows promise in controlling insecticide-resistant thrips in Chinese agriculture
A research team has found that field populations of the thrips Megalurothrips usitatus and Thrips palmi in China have developed high resistance to multiple insecticides, presenting significant control challenges. By utilizing ultraviolet-absorbing fi.....»»
Some CRISPR screens may be missing cancer drug targets
CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or "canc.....»»
To kill the competition, bacteria throw pieces of dead viruses at them
A network of mutual murder ensures that diverse populations of bacteria survive. Enlarge / This is an intact phage. A tailocin looks like one of these with its head cut off. (credit: iLexx) Long before humans became inte.....»»
Huge telehealth fraud indictment may wreak havoc for Adderall users, CDC warns
The consequences are dangerous, possibly even deadly, for patients across the US. Enlarge / Ten milligram tablets of the hyperactivity drug, Adderall, made by Shire Plc, is shown in a Cambridge, Massachusetts pharmacy Thursday, J.....»»
Research says high energy fire influences prescribed burn effectiveness
Fighting woody plant encroachment with prescribed burns may be more effective than land managers previously thought......»»
Improving the ability of phototherapy to stimulate the systemic immune response to cancer
Phototherapy is a safe and effective method for tumor treatment, including photothermal therapy (PTT) and photodynamic therapy (PDT). PTT refers to the use of laser to activate photothermal conversion agents and use high temperature to kill tumor cel.....»»
Upper surface of coastal waters can accumulate bacteria and antibiotics, study finds
Antibiotics in the uppermost water surface, known as the sea surface microlayer, can significantly affect the number of bacteria present and contribute to the adaptation of marine bacteria against widely used antibiotics. In new research presented at.....»»
AI enables faster, more effective antibiotic treatment of sepsis
Sepsis is a life-threatening infection complication and accounts for 1.7 million hospitalizations and 350,000 deaths annually in the U.S. Fast and accurate diagnosis is critical, as mortality risk increases up to 8% every hour without effective treat.....»»
Resistant breeding lines for leafminer, corky root and downy mildew in lettuce
A study, published in the journal HortScienceand released by the USDA-Agricultural Research Service, announced the development of new breeding lines of green leaf, red leaf, and romaine lettuce with remarkable resistance to leafminer, corky root, and.....»»
A compound produced by symbiotic bacteria promotes in vitro protein synthesis
A research team led by Associate Professor Atsushi Nakabachi of the Toyohashi University of Technology Research Center for Agrotechnology and Biotechnology has revealed that the compound diaphorin produced by an insect symbiotic bacterium promotes th.....»»
New dart launcher may be a better way to inject animals with drugs
A new type of dart launcher has been developed as a safer and more cost-effective alternative to firearms or air guns to inject animals with drugs or tracking chips......»»
Research reveals plant pathogens repurpose phage elements for bacterial warfare
Bacteriophages, viruses that attack and destroy bacteria, are everywhere in the natural world where they play a vital role in regulating microbe populations in ways that are not yet well understood......»»