Novel drug prevents amyloid plaques, a hallmark of Alzheimer"s disease
Researchers have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques......»»
A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»
Study presents strategy to stamp out illicit market for cannabis amid wave of policy shifts in North America
It's been five years since Canada stepped into the forefront of cannabis legalization, setting a significant precedent in the realm of drug policy. With Canada and 24 US states now embracing recreational cannabis, the battle against the illegal marke.....»»
Mechanism of grafting Prunus sp. to control crown gall disease by regulating the rhizosphere environment
Grafting is a traditional and significant strategy to suppress soil-borne diseases, such as the crown gall disease caused by tumorigenic Agrobacterium and Rhizobium. Root exudates and the rhizosphere microbiome play critical roles in controlling crow.....»»
AI tool recognizes serious ocular disease in horses
Colloquially known as moon blindness, equine recurrent uveitis (ERU) is an inflammatory ocular disease in horses, which can lead to blindness or loss of the affected eye. It is one of the most common eye diseases in horses and has a major economic im.....»»
Africa"s megacities threatened by heat, floods, disease—action needed to start greening, adapt to climate change
Cities cover just 3% of the planet. But they emit 78% of all global greenhouse gas emissions, absorb 80% of final global energy (what consumers use) and consume 60% of clean drinking water......»»
New method could cut waste from drug production
Scientists have developed a sustainable new way of making complex molecules, which could greatly reduce waste produced during drug manufacturing, a study suggests......»»
Can climate change accelerate transmission of malaria? New research sheds light on impacts of temperature
Malaria is a mosquito-borne disease caused by a parasite that spreads from bites of infected female Anopheles mosquitoes. If left untreated in humans, malaria can cause severe symptoms, health complications and even death......»»
Study recommends ending use of drug dogs, reducing police presence at future Mardi Gras
A study of policing at WorldPride and Mardi Gras events in 2023 found it was heavy-handed and damaging to its relationship with the LGBTQIA+ community......»»
Imaging technique shows new details of peptide structures
A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies—stacks of peptides that include amyloid beta, most notably associated with Alzheimer's disease......»»
Fragments of bird flu virus genome found in pasteurized milk, FDA says
The test cannot tell if the virus is live. The FDA still assess milk supply as safe. Enlarge / Cows being milked (credit: Getty | Edwin Remsberg) The Food and Drug Administration on Tuesday announced that genetic fragmen.....»»
Researchers uncover natural variation in wild emmer wheat for broad-spectrum disease resistance
Bread wheat is one of the most important staple crops for millions of people and is apparently the largest cultivated and traded cereal worldwide. Bread wheat is a hexaploid species with three subgenomes (2n = 6x = 42, AABBDD) that has undergone two.....»»
New toolkit makes molecular dynamics simulations more accessible
Molecular dynamics (MD) simulations have become a powerful tool in the ever-growing fields of molecular biology and drug development. While many MD simulation techniques exist, parallel cascade selection MD (PaCS-MD) is a particularly useful one when.....»»
Why a GameCube/Wii emulator may not be possible on the iOS App Store
DolphiniOS dev says barring just-in-time compilation prevents playable performance. Enlarge / Don't expect to see this on the iOS App Store any time soon. (credit: OatmealDome) Last week's release of the Delta emulation.....»»
Scientists find common genes defending coffee plants against devastating disease
Arabica coffee is the most economically important coffee globally and accounts for 60% of coffee products worldwide. But the plants it hails from are vulnerable to a disease that, in the 1800s, devastated Sri Lanka's coffee empire......»»
Previously unknown details of aphids in flight to contribute to improved crop security
Researchers led by a scientist at Keele University in Staffordshire have studied the previously unknown flight mechanisms of a common crop pest, to learn more about their movements in a bid to improve food security and prevent the spread of disease......»»
Researchers set new standards for nanoparticles, helping patients with MS, ALS, Parkinson"s disease
Is it possible for nanoparticles to go through the digestive system and deliver medicine directly to the brain tissue? Researchers from Michigan State University say yes, and their latest findings are expected to benefit patients with neurodegenerati.....»»
Coal train pollution increases health risks and disparities, research warns
Trains carrying loads of coal bring with them higher rates of asthma, heart disease, hospitalization and death for residents living nearest the rail lines, according to a new study from the University of California, Davis......»»
Redgate Monitor Enterprise prevents unauthorized access to sensitive information
Redgate has launched an enterprise version of its popular database monitoring tool, providing a range of new features to address the challenges of scale and complexity faced by larger organizations. Redgate Monitor Enterprise offers advanced capabili.....»»
Disease-resistant strains of carp provide advancements in aquaculture, enhance gefilte fish quality
A new study led by Prof. Lior David from the Faculty of Agriculture at the Hebrew University investigated the infectivity of disease-resistant and susceptible fish by examining their roles as shedders (infecting) and cohabitants (infected) in various.....»»
Multi-drug resistant bacteria found on International Space Station mutate to become functionally distinct
Principal Investigator Dr. Kasthuri Venkateswaran of NASA's Jet Propulsion Laboratory led a team that studied 13 strains of the bacterial species Enterobacter bugandensis that were isolated from the International Space Station (ISS). E. bugandensis i.....»»