New time-resolved ultraviolet photodissociation mass spectrometry strategy for target protein stability analysis
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle structure dynamics is st.....»»
Webb offers best glimpse ever into icy planetesimals of early solar system
New studies led by researchers at the University of Central Florida offer for the first time a clearer picture of how the outer solar system formed and evolved based on analyses of trans-Neptunian objects (TNOs) and centaurs......»»
Scientists recreate molecular timers to control nanomachine activation rates
Living organisms monitor time—and react to it—in many different ways, from detecting light and sound in microseconds to responding physiologically in pre-programmed ways, via their daily sleep cycle, monthly menstrual cycle, or to changes in the.....»»
Arctic snow shows up to 71 times more PFAS during sunny months
PFAS refers collectively to the thousands of man-made chemicals that take a very long time to break down in nature. None of these substances occur naturally—also called forever chemicals, and several are suspected of negatively affecting humans and.....»»
New strategies enhance stability of metal nanoparticles in green hydrogen production
Efficient and durable low-cost catalysts are essential for green hydrogen production and related chemical fuel production, both vital technologies for the transition to renewable energy. Research in this field increasingly focuses on metal exsolution.....»»
Molecular gardening: New enzymes discovered for protein modification pruning
Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including cancer and neurodegenerative disorders......»»
Machine learning offers new framework for heterogeneous catalyst data analysis
Machine learning (ML) transforms the design of heterogeneous catalysts, traditionally driven by trial and error due to the complex interplay of components. BIFOLD researcher Parastoo Semnani from the ML group of BIFOLD Co-Director Klaus-Robert Mülle.....»»
White House unveils new climate goals weeks before Trump"s return
President Joe Biden's administration on Thursday unveiled a new climate target under the landmark Paris accord, just weeks before Donald Trump's return to the White House threatens to upend US efforts to combat global warming......»»
Storm fears overshadow India coast decades after tsunami
The deadly tsunami that swamped India's southern coast two decades ago was a one-off disaster, but storms that are growing ever more intense spark panic each time howling gales whip up waves......»»
The Backbone One would be an ideal game controller—if the iPhone had more games
It works well, but there still aren't enough modern, console-style games. In theory, it ought to be as good a time as ever to be a gamer on the iPhone. Classic console emulators h.....»»
New method maps hundreds of proteins in cell nuclei simultaneously
Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time. The method, called ChIP–DIP (Chromatin ImmunoPrecipitation Done In Parallel), is a versatile tool f.....»»
Old moon, young crust: Violent volcanism may mean the moon is much older than previously thought
After its formation, the moon may have been the scene of such immense volcanic activity that its entire crust melted several times and was completely churned through. At that time, the moon orbited significantly closer to Earth than today. The result.....»»
Comprehensive analysis reveals hidden genomic evolution of brown algae
Covering over 70% of Earth's surface, the oceans are home to countless life forms that maintain ecological balance and support human well-being. Among these, brown algae (Phaeophyceae) play a crucial role in sustaining coastal habitats, supporting ma.....»»
Nintendo Switch Year in Review 2024 is live: Here’s how to see your stats
Are you curious about how you spent your time on the Nintendo Switch this year? If so, you'll want to check out your Year in Review 2023. Here's how to do it......»»
Steam Replay 2024 is live — here’s how to see yours
The year's almost over, so it's finally time to look back at your year of PC gaming with the Steam Replay 2024......»»
Ray-Ban Meta Smart Glasses get real-time visual AI and translation
Two long-awaited AI features are coming to the Ray-Ban Meta Smart Glasses as part of an upcoming update......»»
This Lenovo ThinkPad is usually $2,399 — today it’s $984
The Lenovo ThinkPad T14 is a great business laptop, and it's even more appealing now that it's on sale at Lenovo for a limited time only......»»
Elevation Lab has a gadget that gives an AirTag a ten-year battery life
Elevation Lab's TimeCapsule is a case for AirTag that adds more battery life, extending the time between battery changes to up to ten years.ElevationLab's TimeCapsule AirTag Battery Case - Image credit: ElevationLabApple's AirTag is extremely useful.....»»
Deals: iPhone 15 Pro $349 off, M2 iPad Air $100 off, Find My gear from $28, MagSafe chargers, more
Our roundup of the best Apple gear deals you can still land in time for the big day has been updated but we have some new deals to scope out today as well. We have the most affordable M2 iPad Air at $100 off, premium renewed iPhone 15 Pro units at $3.....»»
AirTag just got a new feature in iOS 18.2, here’s how to use it
iOS 18.2 introduced a new feature for and other items in the Find My app, and it may just save you a lot of stress and trouble the next time you lose something important. more….....»»
Steve Jobs" original Macintosh demo site is now rubble
It was the site of the original Steve Jobs launch of the Mac and it lasted until the time of the M4 Mac mini, but finally the famous Flint Center Apple event site is being demolished.The Flint Center being demolished — image credit: Karl Mondon/Bay.....»»