New technique provides insight into how proteins involved in cellular processes communicate via extracellular vesicles
One way that cells communicate with one another is through the secretion and uptake of extracellular vesicles (EVs). EVs convey a multitude of cargoes, including proteins, lipids and nucleic acids. Their uptake affects the function of recipient cells.....»»
New technique points to unexpected uses for snoRNA across many cell types
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) are a common but overlooked.....»»
A technique for estimating the mass of gigantic filaments of dark matter
How do you weigh one of the largest objects in the entire universe? Very carefully, according to new research......»»
AI tool can engineer "better, faster, stronger" proteins
Nature is adept at designing proteins. Scientists are even better. But artificial intelligence holds the promise of improving proteins many times over. Medical applications for such "designer proteins" range from creating more precise antibodies for.....»»
Origin of life research finds RNA can favor both left- and right-handed proteins
The mystery of why life uses molecules with specific orientations has deepened with a discovery that RNA—a key molecule thought to have potentially held the instructions for life before DNA emerged—can favor making the building blocks of proteins.....»»
Transparent worms with glowing proteins may help fertility treatments
The development of maternal egg cells is pivotal for survival—but also precarious. During meiosis, the DNA-containing chromosomes can easily be broken or lost, causing infertility, miscarriage or genetic disorders like Down syndrome. Scientists hav.....»»
New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the nucleus to the site of protein translation in the cytopl.....»»
From traditional to technological: Using laser Doppler vibrometry for fresco conservation
Fresco painting, a technique that dates back to antiquity, involves applying dry pigments to wet plaster, creating stunning artwork that can last for centuries. Over time, however, these masterpieces often face degradation due to delamination, where.....»»
DNA repair by cooperation between proteins: A look inside the cell"s repair hub
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells......»»
Actfore TRACE reduces keystrokes and expedites data extraction
Actfore unveiled TRACE (Targeted Retrieval and Automated Content Extraction), an auto-extraction feature to accelerate and improve the accuracy of data mining processes for breach notification list generation. TRACE will be integrated into all future.....»»
Making Mars"s moons: Supercomputers offer "disruptive" new explanation
A NASA study using a series of supercomputer simulations reveals a potential new solution to a longstanding Martian mystery: How did Mars get its moons? The first step, the findings say, may have involved the destruction of an asteroid......»»
Cracking the recipe for perfect plant-based eggs
Hint: It involves finding exactly the right proteins. An egg is an amazing thing, culinarily speaking: delicious, nutritious, and versatile. Americans eat nearly 100 billion of th.....»»
Researchers discover the essential role of light in the organization of retinal cells
New work from the laboratory of Michel Cayouette, Director of the Cellular Neurobiology Research Unit at the Montreal Clinical Research Institute (IRCM) and Professor in the Faculty of Medicine at the Université de Montréal, reveals for the first t.....»»
New tool to map protease specificity may pave the way for improved treatments
FMI researchers have developed a new tool that maps how proteases—enzymes that process proteins—cut their targets. This innovation offers new insight into the highly selective nature of proteases, which were previously seen as indiscriminate degr.....»»
Researchers develop pioneering monitoring technique to help build mangrove resilience
Mangroves are remarkable ecosystems home to amazing biodiversity, dense vegetation, and conditions that capture large quantities of carbon. Since they occur in warm, tropical, and subtropical coastal regions, they also take the brunt of the impact fr.....»»
Young planet discovery could provide new insight into planet formation
The detection of a giant planet that transits a very young star is reported in Nature. The findings indicate that this is the youngest transiting planet found to date......»»
Self-assembling proteins can be used for higher performance, more sustainable skincare products
If you have a meticulous skincare routine, you know that personal skincare products (PSCPs) are a big business. The PSCP industry will reach $74.12 billion USD by 2027, with an annual growth rate of 8.64%. With such competition, companies are always.....»»
Algorithm predicts DNA methylation in ancient specimens, providing insight into human evolution
Research published in Nature Ecology & Evolution introduces a novel method for inferring DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human evolution. As DNA methylation is a key marker of gene.....»»
Cross-IdP impersonation bypasses SSO protections
Cross-IdP impersonation – a technique that enables attackers to hijack the single sign-on (SSO) process to gain unauthorized access to downstream software-as-a-service (SaaS) applications without compromising a company’s primary identity.....»»
CRISPR-based system labels extracellular vesicles with "barcodes" to better understand cell-to-cell communication
Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology......»»
Machine learning and supercomputer simulations predict interactions between gold nanoparticles and blood proteins
Researchers in the Nanoscience Center at the University of Jyväskylä, Finland, have used machine learning and supercomputer simulations to investigate how tiny gold nanoparticles bind to blood proteins. The studies discovered that favorable nanopar.....»»