New strategy decodes dynamic structure of proteins within cells
Protein dynamics play a crucial role in diverse functions. The intracellular environment significantly influences protein dynamics, particularly for intrinsically disordered proteins (IDPs)......»»
Chromatin structure found to play a key role in canine social behavior evolution
A study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also plays a crucial role in gene regulation......»»
New cobalt complex triggers ferroptosis in cancer cells
In programmed cell death, certain signaling molecules initiate a kind of suicide program to cause cells to die in a controlled manner. This is an essential step to eliminate damaged cells or to control the number of cells in certain tissues, for exam.....»»
An affordable tracking microscope to democratize microorganism research
Studying the complex motility patterns of cells and microorganisms is key to understanding their behaviors and biomechanics. However, many conventional microscopes are constrained by fixed lenses and the lack of ability to track organisms over extend.....»»
Visions of Mana’s class system sticks to the series’ roots while still feeling fresh
After spending 10 hours with Visions of Mana, its updated class systems are fun and dynamic while also feeling connected to the its series roots......»»
Light-responsive gene regulation at the mRNA level
Researchers at the University of Bayreuth have established a new optogenetic approach that can control the bacterial production of proteins at the mRNA level using blue light. The new system gates the activation of the genetic substance particularly.....»»
Common equine painkiller disrupts assisted reproduction technique efficiency in mares
Researchers at the Texas A&M School of Veterinary Medicine & Biomedical Sciences (VMBS) have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells—.....»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
House call: A new study rethinks early Christian landmark
Since its discovery by modern researchers a century ago, an ancient structure known as the "Christian building" has become widely considered the cornerstone of early Christian architecture. Constructed around 232 C.E. in the ancient city of Dura-Euro.....»»
Advance in stem cell therapy: New technique for manipulating stem cells opens door to novel treatments
A new technique developed by McGill researchers for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential......»»
AI-driven method enhances electron microscopy imaging capabilities of complex biological systems
Electron microscopy has enabled visualization of the intricate details inside cells. The advancement to 3D electron microscopy, known as volume EM (vEM), has further expanded this three-dimensional, nanoscale imaging capacity. However, trade-offs bet.....»»
Starvation and adhesion drive formation of keratinocyte patterns in skin, research reveals
Fingerprints are one of the best-recognized examples of pattern formation by epithelial cells. The primary cells in the epithelium are the keratinocytes, and they are known to form patterns at the microscopic and macroscopic levels. While factors aff.....»»
Rewriting the evolutionary history of critical components of the nervous system
A new study has rewritten the conventionally understood evolutionary history of certain proteins critical for electrical signaling in the nervous system......»»
International team discovers key protein that helps cells maintain their identity
A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell. The discovery is the result of an international research collaboration, led by Professors Genevieve.....»»
Band of Crusaders looks like The Witcher if it was a strategy game
If you've ever wondered what The Witcher would look like as a strategy RPG, then you'll want to pay attention to upcoming PC indie game Band of Crusaders......»»
A new robotic platform to reproduce and study complex ciliary behavior
Cilia are sensory structures extending from the surface of some cells. These hair-like structures are known to contribute to the sensorimotor capabilities of various living organisms, including humans......»»
Comparing Apple’s latest App Store changes in the EU to Google’s Play Store guidelines
Last week, Apple announced changes to its compliance strategy with the Digital Markets Act in the European Union. These changes apply to apps that link to a web page and include a new fee structure centered around the Initial Acquisition Fee and the.....»»
Researchers identify body"s "quality control" regulator for protein folding, could lead to targeted treatments
Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-.....»»
New forest condition monitor shows dynamic changes in forests resulting from extreme climate change events
According to the German Federal Ministry of Food and Agriculture (BMEL), large parts of the German forest show an increase in damage as a result of the extreme drought period in Germany during recent years. However, hardly any data is available captu.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
Align or die: Revealing unknown mechanism essential for bacterial cell division
A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto "dying to align": Misaligned filaments "die" spontaneously to form a ring structure at the center of the dividing cell. The stud.....»»