New route to the synthesis of P-chiral compounds
Chiral phosphines are one of the most commonly used ligands in assymetric metal catalysis for the synthesis of various useful drugs and pharmaceuticals. Have you ever wondered how to obtain them? Most of the so-called chiral phosphines are C-stereoge.....»»
Synthesis of two new carbides provides perspective on how complex carbon structures could exist on other planets
Researchers at the University of Bayreuth have gained new insights in the field of high-pressure carbon chemistry: They synthesized two new carbides—compounds of carbon and another chemical element—with unique structures. The results may provide.....»»
Study shows the longer spilled oil lingers in freshwater, the more persistent compounds it produces
Oil is an important natural resource for many industries, but it can lead to serious environmental damage when accidentally spilled. While large oil spills are highly publicized, every year, there are many smaller-scale spills into lakes, rivers, and.....»»
Team reports on relationship between contents of diosgenin and brassinosteroids in Dioscorea zingiberensis
Diosgenin, a secondary metabolite isolated from the Dioscorea spp. plant family, is an irreplaceable and ideal starting material for the synthesis of steroid hormone drugs. Dioscorea zingiberensis is the world's most desirable and important plant sou.....»»
A new method for enzymatic synthesis of potential RNA therapeutics
A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases, enzymes commonly used for the synthesis of DNA,.....»»
Pomegranate power: Unlocking sustainable antimicrobial solutions from peels
Pomegranates, known for their rich phenolic content, have been explored for their potential as natural antimicrobials. The research focuses on the peel, which contains a high concentration of these beneficial compounds and represents a significant po.....»»
Chemists introduce new copper-catalyzed C-H activation strategy
Inspired by what human liver enzymes can do, Scripps Research chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions are expected to be widel.....»»
Physical field technologies to improve extraction and quality of extracted juices
Consumers are increasingly health-conscious and seek products with minimal additives and preservatives. The modern consumer understands the link between consuming bioactive compounds from fruits and vegetables and the associated health benefits. Henc.....»»
New research could enable more—and more efficient—synthesis of metastable materials
Ion exchange is a powerful technique for converting one material to another when synthesizing new products. In this process, scientists know what reactants lead to what products, but how the process works—the exact pathway of how one material can b.....»»
New benzofuran synthesis method enables complex molecule creation
In the field of organic chemistry, scientists are always looking out for new types of reactions to unlock synthesis routes for challenging compounds. Most of the progress that we have witnessed in pharmaceutics and agrochemicals over the past few dec.....»»
L-cyclodextrins synthesized in the lab for the first time
A team of chemists at Northwestern University has successfully synthesized three L-cyclodextrins in the lab for the first time. In their study, published in the journal Nature Synthesis, the group used a one-pot strategy to achieve the feat......»»
Palladium nanocluster catalyst supports highly efficient and regioselective hydrogenation of epoxides
Alcohols are widely applied in life sciences and the chemical industry. Selective hydrogenation of epoxides using hydrogen molecules as a reductant is considered to be one of the most facile and atom-economical strategies for alcohol synthesis. Howev.....»»
A novel machine learning model for the characterization of material surfaces
Machine learning (ML) enables the accurate and efficient computation of fundamental electronic properties of binary and ternary oxide surfaces, as shown by scientists from Tokyo Tech. Their ML-based model could be extended to other compounds and prop.....»»
New technique lets scientists create resistance-free electron channels
An international research team led by Lawrence Berkeley National Laboratory (Berkeley Lab) has taken the first atomic-resolution images and demonstrated electrical control of a chiral interface state—an exotic quantum phenomenon that could help res.....»»
On-surface synthesis of carbyne: An sp-hybridized linear carbon allotrope
In a study led by Prof. Wei Xu (Interdisciplinary Materials Research Center, School of Materials Science and Engineering, Tongji University) and published in the journal National Science Review, a research team achieved the successful synthesis of a.....»»
Click chemistry: Research team creates 150 new compounds
Cold Spring Harbor Laboratory (CSHL) chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show promise for development as a.....»»
The omnipresence of PFAS—and what we can do about them
Per- and poly-fluoroalkyl substances (PFAS)—also known as "forever chemicals"—are everywhere. Created in the 1940s, these synthetic compounds are an unseen ingredient in many items that we use in our daily lives, like cleaning products, food pack.....»»
Rattlesnakes on California"s Santa Catalina Island have learned that it pays to be unusually aggressive
Discerning what makes rattlesnakes tick is a life's work for researchers like William Hayes. So if he wants to introduce you to the biological complexity that makes them worthy of study, be prepared to follow a deliberately cautious route climbing ov.....»»
Using a cellphone compass to measure tiny concentrations of compounds important for human health
Nearly every modern cellphone has a built-in compass, or magnetometer, that detects the direction of Earth's magnetic field, providing critical information for navigation. Now a team of researchers at the National Institute of Standards and Technolog.....»»
New synthesis platform allows for rapid cancer drug synthesis and testing
Imperial College London researchers have developed a new platform for the synthesis, analysis and testing of new compounds which may one day treat cancer. The findings are published in the journal Angewandte Chemie International Edition......»»
Mapping the best route for a spacecraft traveling beyond the sun"s sphere of influence
The heliosphere—made of solar wind, solar transients, and the interplanetary magnetic field—acts as our solar system's personal shield, protecting the planets from galactic cosmic rays. These extremely energetic particles accelerated outwards fro.....»»