New proteins "out of nothing"
Proteins are the key component in all modern forms of life. Hemoglobin, for example, transports the oxygen in our blood; photosynthesis proteins in the leaves of plants convert sunlight into energy; and fungal enzymes help us to brew beer and bake br.....»»
Profiling artemisinin"s antimalarial mechanism: Research team reveals crucial target proteins
Jigang Wang and colleagues have made significant progress in unraveling the antimalarial mechanisms of artemisinin (ART) and its derivatives. Their latest research, published in the journal Engineering, sheds light on the crucial target proteins and.....»»
The dance of organ positioning: A tango of three proteins
In order to keep track of their environment, cells use cilia, antenna-like structures that can sense a variety of stimuli, including the flow of fluids outside the cell. Genetic defects that cause cilia to malfunction and lose their sensory abilities.....»»
New imaging technique detects virus movement in unprecedented detail
Proteins are the workhorses of biological systems, carrying out their work with extraordinary precision and speed. For years, observing proteins in action has been a significant challenge, as imaging methods often lacked sufficient speed and resoluti.....»»
Dinosaur feathers reveal traces of ancient proteins
Paleontologists at University College Cork (UCC) in Ireland have discovered X-ray evidence of proteins in fossil feathers that sheds new light on feather evolution......»»
Scientists reveal intricate mechanisms cells use to build protein destruction signals
Within the intricate molecular landscape inside of a cell, the orchestration of proteins demands precise control to avoid disease. While some proteins must be synthesized at specific times, others require timely breakdown and recycling. Protein degra.....»»
Google’s AI protein folder IDs structure where none seemingly existed
Two intrinsically disordered proteins form a specific structure ID'ed by AlphaFold. Enlarge (credit: LAGUNA DESIGN) For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt creat.....»»
Researchers enhance the function of natural proteins using "protein Legos"
Johns Hopkins engineers have helped develop and characterize an artificial protein that triggers the same response in the human body as its natural counterpart—a breakthrough that not only has the potential to facilitate the design of drugs to acce.....»»
Matchmaking (with AI) to help proteins pair up
Successful matchmaking with protein molecules is like all other kinds of matchmaking: The two must click for it to work......»»
Mysterious family of microbial proteins hijack crops" cellular plumbing
Many of the bacteria that ravage crops and threaten our food supply use a common strategy to cause disease: they inject a cocktail of harmful proteins directly into the plant's cells......»»
Researchers uncover NSMF protein"s role in relieving DNA replication stress
A team of researchers from the Department of Biological Sciences at UNIST has achieved a significant breakthrough in understanding how brain proteins can help alleviate complications arising from DNA replication stress. This discovery holds immense p.....»»
The role of high hydrostatic pressure in altering bacteria in donkey milk
Donkey milk is popular for its nutritional content and hypoallergenic properties and can be used as an alternative nutritional product for people who are allergic to cow's milk proteins or are immunocompromised. The bacterial composition of donkey mi.....»»
Video: How is ceviche "cooked?"
What does it mean to have "cooked" something? Is heat the only way to break down proteins and transform raw ingredients?.....»»
Why S-linked glycosylation cannot adequately mimic the role of natural O-glycosylation
Protein glycosylation is one of the most important post-translational modifications that can be exploited to improve various aspects of therapeutic proteins and industrial enzymes. Different types of glycosylation have a variety of effects on protein.....»»
Researchers uncover novel physiological functions of CRISPR-Cas guard RNA
How the expression of Cas proteins in bacterial CRISPR-Cas immune system adapts to the constantly changing CRISPR structures and crRNA expression levels has been a long-standing unresolved question......»»
Novel molecular design for enhanced efficacy and safety in radiotheranostics
Radiotheranostics embodies the convergence of diagnostic and therapeutic radiopharmaceuticals into a unified platform. In cancer treatment, radiotheranostic procedures typically involve the use of antibodies that bind to proteins abundantly found on.....»»
Will it slip or will it grip: Scientists ask, "What is snail mucus?"
What is snail mucus? That was the question posed by researchers in a new study that examines the molecular composition of snail mucus. When analyzing the mucus of a common garden snail, they found it contained a complex collection of proteins, some i.....»»
Soluble protein extraction facilitates the salt-induced swelling of pork meat
Salt-induced swelling is a crucial phenomenon in pork meat processing, significantly influencing the meat's water-holding capacity (WHC). Existing theories focus on the role of myofibrillar proteins, especially myosin and actin, in swelling. However,.....»»
How hydrophobicity shapes protein assemblies
Through a nuanced balance of electrical and hydrophobic forces, biological molecules self-assemble into the large functional structures that maintain life's vital functions. Understanding how proteins self-assemble requires knowledge of both forces......»»
New "radar" detects active cellular destroyers
Cells in the human body must adapt their protein balance to certain situations, such as the availability of iron or an infection. These adaptations occur through a complex process in which proteins that are no longer needed or that are toxic are tagg.....»»
Study finds how some ion channels form structures permitting drug delivery
A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine. The discovery is a significant ad.....»»