New lipid nanoparticle-mRNA therapy combats melanoma in mouse models
Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells—which play a key role in immune response—that eradicated tumors and prevented their recurrence in mouse models.....»»
Ketamine pills for depression show positive results in trial—but with caveats
A slow-release oral dose showed good safety, but efficacy is shaky. Enlarge (credit: Getty | RJ Sangosti) After an MDMA therapy for post-traumatic stress disorder dramatically failed to impress Food and Drug Administrati.....»»
AI predicts upper secondary education dropout as early as the end of primary school
An interdisciplinary team of researchers from the University of Jyväskylä, Finland, from the fields of Psychology, Education, and Information Technology have developed the first machine learning models that forecast upper secondary education dropou.....»»
Boosting "natural killer" cell activity could improve cancer therapy
Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells—which kill infected, damaged, or malignant cells in the body—more effective against cancer. The approach, they say, could enable new treatment.....»»
Marine cloud brightening models show unexpected consequences of geoengineering
A combined team of Earth scientists and climate specialists at the University of California San Diego and the National Center for Atmospheric Research has found via modeling that geoengineering projects such as marine cloud brightening can have unexp.....»»
New paradigm in photothermal therapy: Researchers develop ultrasound-assisted photothermal therapy technology
Professor Jin-ho Chang's research team from the Department of Electrical Engineering and Computer Science at DGIST has developed "Ultrasound-assisted photothermal therapy (ULTRA-PTT)" technology that significantly enhances the performance of conventi.....»»
The Steam Deck is the cheapest its ever been in new sale
Thanks to a new sale from Valve, you can now get the 64GB and 512GB Steam Deck LCD models for ridiculously cheap......»»
The 8 best subwoofers for 2024: add boom to your movie or music room
If you’re looking for some extra thump in your home theater system, we recommend investing in a subwoofer. Here are seven of our favorite models for 2024......»»
Top FDA official overrules staff to approve gene therapy that failed trial
Peter Marks overruled three teams and two top directors. Enlarge / Dr. Peter Marks, Director of the Center for Biologics Evaluation and Research within the Food and Drug Administration on March 18, 2021 in Washington, DC. (credi.....»»
Best Dell laptop deals: Cheap laptops starting at $400
If you're on the hunt for Dell laptop deals, we've rounded up the best ones here. Get the Dell XPS 13 for much cheaper than usual, along with other models......»»
Friday deals: Nano-texture M4 iPad Pro all-time low at $135 off, black Magic Keyboard, M2 iPad Air, accessories, more
Friday has rolled back around again and Amazon has rolled back pricing on the 1TB 13-inch nano-texture glass Apple iPad Pro with M4 to its best price ever alongside ongoing offers on the more affordable models. Those deals now sit alongside the best.....»»
New computational tool helps interpret AI models in genomics
Artificial intelligence continues to squirm its way into many aspects of our lives. But what about biology, the study of life itself? AI can sift through hundreds of thousands of genome data points to identify potential new therapeutic targets. While.....»»
Column: EV buyers" remorse is a telling moment in economic history
More likely a blip than a pivot, McKinsey's survey highlights need for affordable models that automakers are developing......»»
How to run Xbox 360 games on macOS Sequoia
Upgrades in macOS Sequoia make it possible to run the Windows-based Xenia Xbox 360 emulator on your Mac. Here's how.Xbox 360 and 360 "S" models.Xbox 360 was the second, third, and fourth generation of Microsoft's game console which launched in 2005......»»
Anthropic introduces Claude 3.5 Sonnet, matching GPT-4o on benchmarks
Claude 3.5 Sonnet is a speedy mid-sized entry in a new family of AI models. Enlarge (credit: Anthropic / Benj Edwards) On Thursday, Anthropic announced Claude 3.5 Sonnet, its latest AI language model and the first in a n.....»»
An efficient protein delivery system with spider minor ampullate silk protein nanoparticles
In a study published in the journal MedComm, researchers have developed an efficient protein delivery carrier based on spider silk proteins (spidroins), derived from Araneus ventricosus minor ampullate silk protein (MiSp). The MiSp-based nanoparticle.....»»
Researchers describe how to tell if ChatGPT is confabulating
Finding out whether the AI is uncertain about facts or phrasing is the key. Enlarge (credit: Aurich Lawson | Getty Images) It's one of the world's worst-kept secrets that large language models give blatantly false answer.....»»
Apple Watch Series 9 GPS + Cell $120 off, unlocked iPhone 15 $680, M4 iPad Pro, Apple Pencil Pro, and more
It is now time to gather up all of today’s best deals on Apple gear and accessories. While we have been tracking solid $100 price drops across a range of Apple Watch Series 9 models as of late, the 45mm GPS + Cell configurations are now even lower.....»»
Thinner design Apple products, bigger screen Apple Watch rumors, more iOS 18 tidbits
Benjamin and Chance are back with a review of this week’s Apple news, including thoughts on the rumored bigger watch sizes coming this fall, Apple’s plans to design thinner iPhone and MacBook Pro models, and the abrupt cancellation of Apple Pay L.....»»
Deals: save up to $155 on the M4 iPad Pro, plus Apple Pencil Pro falls to $119
Amazon has issued some hefty discounts on Apple's new M4 iPad Pro and iPad Air 6, along with dropping the Apple Pencil Pro to the lowest price ever.June iPad deals are heating up at Amazon, and even Apple's newly released models are eligible for stee.....»»
Too young to be so cool: Lessons from three neutron stars
ESA's XMM-Newton and NASA's Chandra spacecraft have detected three young neutron stars that are unusually cold for their age. By comparing their properties to different neutron star models, scientists conclude that the oddballs' low temperatures disq.....»»