New approach uses "cloaked" proteins to deliver cancer-killing therapeutics into cells
An interdisciplinary collaboration has designed a way to "cloak" proteins so that they can be captured by lipid nanoparticles, which are akin to tiny bubbles of fat. These bubbles are small enough to sneak their hidden cargo into living cells, where.....»»
Study reveals how one enzyme hitches a ride on another to recognize tRNA
Imagine your body as a highly organized factory where workers tirelessly assemble proteins around the clock. These proteins are the machines and scaffolds that make up your body and are essential for various functions. In this factory, special delive.....»»
Boosting "natural killer" cell activity could improve cancer therapy
Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells—which kill infected, damaged, or malignant cells in the body—more effective against cancer. The approach, they say, could enable new treatment.....»»
New fluorescent reporting system illuminates accumulation of unfolded proteins in endoplasmic reticulum
The endoplasmic reticulum (ER) is a major organelle responsible for protein folding and trafficking. Protein folding stress in the ER can lead to the accumulation of unfolded or misfolded proteins, known as ER stress, which activates the unfolded pro.....»»
AI-based approach matches protein interaction partners
Proteins are the building blocks of life, involved in virtually every biological process. Understanding how proteins interact with each other is crucial for deciphering the complexities of cellular functions, and has significant implications for drug.....»»
Apple Intelligence goes against the entire Apple ethos — in a good way
Apple's walled garden is getting upended by its more open approach to AI partnerships......»»
Non-coding RNA acts as "superhighway" for gene expression, study finds
The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins—yet it exists in large quantities......»»
Genetic switch in plants can turn simple spoon-shaped leaves into complex leaves with leaflets
The diversity of forms of living organisms is enormous. But how the individual cells together coordinate the formation of organs and tissues in complex organisms is still an open question......»»
3D maps of diseased tissues at subcellular precision
Researchers in the Systems Biology Lab of Professor Nikolaus Rajewsky, at the Max Delbrück Center, have developed a spatial transcriptomics platform, called Open-ST, that enables scientists to reconstruct gene expression in cells within a tissue in.....»»
I thought Motorola’s new $550 Android phone would be great. I was wrong
The new Motorola Edge (2024) promises to deliver flagship-level specs and features at a reasonable $550 price. But is it any good? I reviewed it and found out......»»
Study pushes understanding of how cells migrate
Interactions between two key structures within cells help establish the front-to-back "polarity" that is essential to cell migration, according to a new study by Weill Cornell Medicine researchers......»»
Ethylene oxide emissions from two plants could have raised cancer risks for Illinois residents, report shows
People living near two Lake County industries could face significantly greater risks of developing certain cancers, according to a new federal study based on monitoring of ethylene oxide pollution in surrounding neighborhoods......»»
Scientists explore the vast reservoir of dissolved organic matter in oceans
Few things last very long in the world of the open oceans, it would seem. In the light-filled surface layer, microscopic algae convert carbon dioxide and water into biomass via photosynthesis. Individual cells vanish in a matter of hours or days, ing.....»»
Security Bite: Meta will start using your data to train its AI next week, but you may be able to opt out
9to5Mac Security Bite is exclusively brought to you by Mosyle, the only Apple Unified Platform. Making Apple devices work-ready and enterprise-safe is all we do. Our unique integrated approach to management and security combines state-of-the-art App.....»»
New insights into methyl jasmonate-induced saponin biosynthesis in the balloon flower
Platycodon grandiflorus, commonly known as balloon flower, is renowned for its medicinal properties, primarily due to its rich saponin content. Saponins are known for their anti-inflammatory, anti-cancer, and immune-boosting properties, making P. gra.....»»
Inspired by nature: Synthetic nightshade molecule effective against leukemia cells
Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia cells......»»
What is forensic genetic genealogy? Technique used in Rachel Morin case is scantly regulated
Authorities touted the use of a growing, powerful, yet contentious forensic technique to bring the search for a suspect in last year's killing of Rachel Morin to a long-awaited close......»»
Radioactive drugs strike cancer with precision
Tumor-seeking radiopharmaceuticals promise targeted treatments with fewer side effects. Enlarge / Pharma interest and investment in radiotherapy drugs is heating up. (credit: Knowable Magazine) On a Wednesday morning in.....»»
An efficient protein delivery system with spider minor ampullate silk protein nanoparticles
In a study published in the journal MedComm, researchers have developed an efficient protein delivery carrier based on spider silk proteins (spidroins), derived from Araneus ventricosus minor ampullate silk protein (MiSp). The MiSp-based nanoparticle.....»»
New insights into how cell shape influences protein transport rates
When a cell spreads out or changes its shape to adapt to its environment, the transport rate of proteins between the nucleus and cytoplasm changes. Previously, scientists assumed this change was caused by a shift in the size of the nuclear envelope's.....»»
Scientists discover surprising link between ancient biology and restricted human hair growth
University of Manchester scientists have linked one of the ways that cells respond to stressful conditions with restricted healthy hair growth......»»