Must mRNA be cloaked in a lipid coat to serve as a vaccine?
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»
Salt marshes put to the test in wave flume
Can salt marshes serve as a natural solution for flood protection? Researchers of the project "Living Dikes" transported 62 big blocks of salt marshes, containing soil and vegetation, from the coast of Friesland to the Delta Flume at Deltares. After.....»»
Research seeks to develop mRNA lipid nanoparticles for next-generation oral cancer tumor suppressor therapy
A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of t.....»»
US government agencies demand fixable ice cream machines
McFlurries are a notable part of petition for commercial and industrial repairs. Enlarge / Taylor's C709 Soft Serve Freezer isn't so much mechanically complicated as it is a software and diagnostic trap for anyone without authori.....»»
Danish chef to launch gourmet dining to stratosphere
Danish chef Rasmus Munk wants to take high-end cuisine to the edge of space, with plans to serve up a stratospheric dining experience in 2025, his restaurant said Thursday......»»
New discovery reveals how the egg controls sperm entry
After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo. This is according to a new study led by researchers at Karolinska Institutet a.....»»
Advancing tissue engineering with shape memory hydrogels
One of the primary goals in the field of tissue engineering and regenerative medicine is the development of artificial scaffolds that can serve as substitutes for damaged tissue. These materials must ideally resemble natural tissue and must have the.....»»
Team makes progress with fluorescent dyes to better visualize lipid membrane order in live cells
A new solvatochromic probe could help shed light on the relationship between lipid membrane fluidity and various cellular functions, report scientists at Tokyo Institute of Technology and Kyushu University. Thanks to an innovative design, the propose.....»»
Q&A: How Instagram influencers profit from anti-vaccine misinformation
While Instagram might have a reputation for superficiality—a realm of exquisitely filtered images—it is now eclipsing other social media as a news source. The platform is increasingly filled with information, some of it pernicious and distributed.....»»
How cells manage their mRNA stockpile and its output
In a typical cell, genes encoded in DNA are used to make messenger RNA (mRNA), which is used to make proteins, and this process of gene expression keeps the cell running. Gene expression is regulated in each cell such that specific genes are turned o.....»»
Early experiments show Ebola-fighting potential of engineered bacteria
Since its 1976 emergence in Africa, the Ebola virus has proven an especially lethal contagion, killing roughly 50% of the people who contract it. The 2019 FDA approval of a vaccine, combined with the subsequent development of two antibody-based drugs.....»»
Apple Vision Pro one month review: a new reality is setting in
Living with Apple Vision Pro for the past month has changed everything and nothing. It is a new computing paradigm stuck doing the same things the old one did with a new coat of paint.Apple Vision Pro review: one month laterIt's early days for Apple.....»»
Study highlights urgency of parasitic wasp release to save native bird
Researchers with the University of Minnesota hope to release highly specialized parasitic wasps to serve as a biological control method to save Darwin's finches from a dire threat: the invasive avian vampire fly, Philornis downsi......»»
Research milestone reached as healthy koala leaves treatment program
In a research milestone, the first koala to receive the QUT-developed chlamydia vaccine has been released from the program and back into the wild......»»
8 in 10 lizards could be at risk due to deforestation
In Colorado, people flock to the Rocky Mountains when the summer heat gets unbearable. Animals seek shelter too when temperatures become extreme, and forests serve as critical sanctuaries for small tree-dwelling animals like lizards......»»
Lipid nanoparticles research closing in on genetic treatments for hereditary lung disease, vision loss
Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and in.....»»
The Kia EV9 is the template for a modern car interior — here’s why
The interior of the Kia EV9 is comfortable and pleasant to be in. In fact, it should serve as a template for carmakers......»»
How to Make the Most of Your Company Intranet
Company intranets serve as indispensable tools for fostering communication, collaboration, and knowledge sharing within organizations. Yet, despite their potential, many intranets often fall short of delivering maximum value due to underutilization o.....»»
Denis Villeneuve breaks down the evolution of sandworms in "Dune: Part Two"
The sandworms we meet in "Dune: Part Two" serve a different role from those in "Dune." Director Denis Villeneuve tells us why. The sandworms we see in Dune: Part Two couldn't be farther from those we see in the first Dune. Yes, they share the s.....»»
Hydrogel spheres compose a microporous structure for localized mRNA delivery
In a significant leap forward in the realm of regenerative medicine, a team at the Terasaki Institute for Biomedical Innovation has introduced a pioneering approach to mRNA therapy using microspheres made of gelatin methacryloyl (GelMA)—a gelatin-b.....»»
BYD says Mexico plant would not export to U.S.
BYD is looking for a site in Mexico for an assembly plant to serve the local market, company says......»»