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Morphological fingerprinting could help identify side effects and new bioactive compounds in drug discovery

Pharmaceutical researchers speak of a hit when they come across a promising substance with a desired effect in early drug discovery. Unfortunately, hits are rarely bull's-eyes, often showing undesirable side effects that not only complicate the searc.....»»

Category: topSource:  informationweekJan 28th, 2022

Over half of Americans say lowering health care costs is among most important issues in deciding their presidential pick

Lowering the cost of health care and prescription drug prices and protecting Medicare and Social Security are among the most important issues for Americans in determining their vote for president, according to a new national West Health-Gallup Poll r.....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

New insights into sauropod evolution: Discovery of tail clubs in India

A new University of Michigan study of dinosaur fossils from India has revealed that the sauropod dinosaur Kotasaurus yamanpalliensis wielded a bony tail club......»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Scientists uncover light absorbing properties of achiral materials

Researchers at the University of Ottawa have made a discovery that changes what we know about light and materials. They found that engineered achiral (symmetric) materials, called achiral plasmonic metasurfaces, can absorb light differently depending.....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Attacks on health care during war are becoming more common, creating devastating ripple effects

The head of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, has warned attacks on health-care workers, patients and facilities "must not become the norm.".....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Discovery of 3,775-year-old preserved log supports "wood vaulting" as a climate solution

A new study published in the journal Science suggests that an ordinary old log could help refine strategies to tackle climate change......»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Lunar dust dynamics: Unveiling the charging properties and particle behavior of Chang"e-5 samples in an electric field

A study published in Engineering has shed new light on the behavior of lunar regolith particles under the influence of an external electric field, a discovery that could revolutionize space exploration and lunar resource utilization. The research, co.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024

Machine learning accelerates discovery of high-temperature alloys

In a study recently published in Engineering, scientists from the University of Science and Technology Beijing, Guangdong Ocean University, and AiMaterials Research LLC have demonstrated a novel method to accelerate the discovery of refractory high-e.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024

How a protein keeps gene clusters quiet in the cell nucleolus

In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»

Category: topSource:  informationweekRelated NewsSep 27th, 2024

Seal species carries "genetic scars" after being hunted to the edge of extinction, new research reveals

Northern Elephant seals have staged a remarkable comeback after narrowly escaping extinction by hunting, but new research reveals lasting genetic effects in the present population......»»

Category: topSource:  informationweekRelated NewsSep 27th, 2024

How iron and metabolic constraints can aid gene discovery for photosynthesis and biofuel production

The single-cell green alga Chromochloris zofingiensis is an emerging model organism for photosynthesis and metabolism research. Previous research has shown that with the addition of glucose, Chromochloris zofingiensis shuts off photosynthesis, rerout.....»»

Category: topSource:  informationweekRelated NewsSep 27th, 2024

Plant lineage study provides insights into the ecological and evolutionary effects of different reproductive strategies

Hang Sun's group from Kunming Institute of Botany, Chinese Academy of Sciences has demonstrated the ecological and evolutionary effects of changes in plant reproductive strategies on phylogenetic evolution. The study is published in the journal Scien.....»»

Category: topSource:  informationweekRelated NewsSep 27th, 2024

Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells

Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»

Category: topSource:  theglobeandmailRelated NewsSep 27th, 2024

Orbital angular momentum monopoles discovery propels orbitronics forward in energy-efficient tech

Orbital angular momentum monopoles have been the subject of great theoretical interest as they offer major practical advantages for the emerging field of orbitronics, a potential energy-efficient alternative to traditional electronics. Now, through a.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024

New method enables noninvasive plant magnetic resonance imaging

The "omics" technologies—genomics, transcriptomics, proteomics, and metabolomics—are at the forefront of discovery in modern plant science and systems biology. In contrast to the rather static genome, however, the metabolome and the products meas.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024

AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery

A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»

Category: topSource:  theglobeandmailRelated NewsSep 26th, 2024

Existence of an Earth-like planet around a dead sun offers hope for our planet"s ultimate survival

The discovery of an Earth-like planet 4,000 light years away in the Milky Way galaxy provides a preview of one possible fate for our planet billions of years in the future, when the sun has turned into a white dwarf, and a blasted and frozen Earth ha.....»»

Category: topSource:  physorgRelated NewsSep 26th, 2024

Advancing synthetic Ephedra-type alkaloids with a two-step enzymatic approach

Ephedra-type alkaloids, a class of naturally occurring compounds derived from plants in the genus Ephedra, have long held interest in the pharmaceutical industry due to their stimulant and airway widening effects. These alkaloids are used for the tre.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Semimetal-induced covalency achieves high-efficiency electrocatalysis for platinum intermetallic compounds

Compared with other types of batteries, proton exchange membrane fuel cells have the advantages of high discharge power and no pollution, which is also an important carrier for hydrogen energy conversion and utilization. Platinum intermetallic compou.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Ingredients used in chewing gum help tilapia survive cold climates

Two common ingredients in ordinary chewing gum—Arabic gum and lecithin—have been found to help improve the overall health of tilapia, helping these fish survive better even in cold climates. This discovery paves the way for raising tilapia for fo.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Twice as many women as men were buried in the megalithic necropolis of Panoría, study reveals

A multidisciplinary research team led by the Archaeometry research group of the University of Tübingen and the GEA research group of the University of Granada made a surprising discovery in the megalithic necropolis of Panoría (Granada, Spain): twi.....»»

Category: topSource:  theglobeandmailRelated NewsSep 25th, 2024