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Molecular mechanism of ZDHHC18-mediated palmitoylation of cGAS in innate immunity inhibition

Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids......»»

Category: topSource:  physorgMay 12th, 2022

New study finds the malaria parasite generates genetic diversity using an evolutionary "copy-paste" tactic

By dissecting the genetic diversity of the most deadly human malaria parasite—Plasmodium falciparum—researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have identified a mechanism of 'copy-paste' genetics that increases the genetic.....»»

Category: topSource:  physorgRelated NewsMar 7th, 2024

Aroma compound found to reduce the effects of drought, improve productivity of tomato plants

Tomato plants emit a scent to resist bacterial attacks. This aroma—or volatile compound—is hexenyl butanoate (HB). A team from the Research Institute for Plant Molecular and Cellular Biology (IBMCP), a joint center of the Universitat Politècnica.....»»

Category: topSource:  physorgRelated NewsMar 7th, 2024

Natural tech for "dimming" genes brings transformative potential to agriculture

Until the 1992 advent of a tomato that could delay softening, the fruit was picked green to withstand shipping. The delayed-softening trait was an example of the gene-silencing technique RNA interference, RNAi, before the underlying mechanism was und.....»»

Category: topSource:  informationweekRelated NewsMar 7th, 2024

Scientists reveal molecular mysteries to control silica scaling in water treatment

Collaborative research that combined experiments at Yale University and molecular dynamics simulations at the Department of Energy's Oak Ridge National Laboratory provides new insights into solving a major technical obstacle to efficient and sustaina.....»»

Category: topSource:  marketingvoxRelated NewsMar 6th, 2024

Microalgae with unusual cell biology could lead to improved understanding of harmful algal blooms

What are the molecular processes in a unicellular marine algae species that can cause harmful algal blooms? A research team led by microbiologist Prof. Dr. Ralf Rabus from the University of Oldenburg (Germany) has conducted the first detailed analyse.....»»

Category: topSource:  physorgRelated NewsMar 6th, 2024

The role of PbrChiA chitinase in ROS regulation and antifungal activity

Pear ring rot, a significant threat to pear production, is caused by Botryosphaeria dothidea, leveraging the complex dynamics of reactive oxygen species (ROS) during infection. Initially, plants employ their innate immune system, detecting pathogens.....»»

Category: topSource:  theglobeandmailRelated NewsMar 5th, 2024

Communication between rotors in molecular motor observed for the first time

A pair of chemists at the University of Groningen in the Netherlands, has observed communication between rotors in a molecular motor. In their study, reported in the Journal of the American Chemical Society, Carlijn van Beek and Ben Feringa conducted.....»»

Category: topSource:  physorgRelated NewsMar 5th, 2024

Ballistic transport in long molecular wires: Porphyrin nanoribbons

The conductance of classical electric components typically decays with increasing length. In general, this is also the same behavior found at the nanoscale with 1D molecular wires. Now, researchers have demonstrated that, once more, things are differ.....»»

Category: topSource:  physorgRelated NewsMar 5th, 2024

A new type of metallacrown ether based on polyoxometalate opens research opportunities

Crown ethers were discovered in 1967. They were then modified by adding a metal-containing unit, creating metallacrown ethers. These metallacrown ethers have been the subject of intensive research. Depending on the molecular makeup of the metallacrow.....»»

Category: topSource:  theglobeandmailRelated NewsMar 1st, 2024

Novel RNA- or DNA-based substances can protect plants from viruses, scientists show

Individually tailored RNA or DNA-based molecules are able to reliably fight off viral infections in plants, according to a new study by the Martin Luther University Halle-Wittenberg (MLU) published in the International Journal of Molecular Sciences......»»

Category: topSource:  physorgRelated NewsFeb 29th, 2024

Research team reveals cellular and molecular basis of spur development in Impatiens uliginosa

As an important reproductive organ of angiosperms, flowers have a clear purpose and adaptive significance in their various characteristics. As a typical floral evolutionary feature, the floral spur is a tubular structure extending from the petal, whi.....»»

Category: topSource:  physorgRelated NewsFeb 29th, 2024

Unlocking the mechanism of pineapple internal browning

Internal browning (IB) is a significant post-harvest issue in pineapples, impacting fruit quality and leading to substantial losses, yet its mechanism remains poorly understood. Studies have shown that the accumulation of phenolic compounds plays a k.....»»

Category: topSource:  physorgRelated NewsFeb 29th, 2024

Study elucidates regulation mechanism for electrocatalytic nitrate reduction

A research team led by Prof. Zhang Haimin from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has conducted a systematic study on the regulation mechanism of heterostructure bimetallic phosphide electrocatalysts to improv.....»»

Category: topSource:  physorgRelated NewsFeb 29th, 2024

Molecular mechanism of transmembrane bilirubin transport by human ABCC2 transporter revealed

The metabolic process of bilirubin has been a focus of medical research since the abnormal accumulation of bilirubin has been found to be associated with a variety of diseases. Bilirubin is a substance produced by the breakdown of aging or damaged re.....»»

Category: topSource:  physorgRelated NewsFeb 29th, 2024

Scientists discover why ripe fruit is more susceptible to necrotrophic pathogens than unripe fruit

In a recent study published in Molecular Plant, researchers have elucidated the mechanism underlying the increased susceptibility to necrotrophs during fruit ripening and have developed a rapid strategy to improve tomato fruit resistance to necrotrop.....»»

Category: topSource:  physorgRelated NewsFeb 28th, 2024

How molecular "handedness" emerged in early biology

Molecules often have a structural asymmetry called chirality, which means they can appear in alternative, mirror-image versions akin to the left and right versions of human hands. One of the great mysteries about the origins of life on Earth is that.....»»

Category: topSource:  physorgRelated NewsFeb 28th, 2024

Study reveals accelerated soil priming under climate warming

A first-of-its-kind study led by researchers at the University of Oklahoma highlights a crucial biosphere feedback mechanism and its effects on releasing soil carbon into the atmosphere......»»

Category: topSource:  physorgRelated NewsFeb 28th, 2024

Light stimulates a new twist for synthetic chemistry

Molecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more......»»

Category: topSource:  physorgRelated NewsFeb 28th, 2024

Scientists develop rapid gene-screening platform to boost disease resistance in crops

Scientists at CSIRO, Australia's national science agency, have achieved a breakthrough in molecular plant pathology, marking a technological leap forward for breeding durable disease-resistant crops......»»

Category: topSource:  marketingvoxRelated NewsFeb 26th, 2024

Research provides insight into constructing gene regulatory networks

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes. Transcriptional re.....»»

Category: topSource:  physorgRelated NewsFeb 23rd, 2024