Molecular mechanism of ZDHHC18-mediated palmitoylation of cGAS in innate immunity inhibition
Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids......»»
Click chemistry: Research team creates 150 new compounds
Cold Spring Harbor Laboratory (CSHL) chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show promise for development as a.....»»
Team develops portable swept-source Raman spectrometer for chemical and biomedical applications
In 1928, Indian physicist Sir C. V. Raman and his colleague K. S. Krishnan discovered that when light interacts with matter, parts of the scattered light undergo changes in energy due to interaction with molecular vibrations, resulting in what is kno.....»»
New research shows key molecules within nerve cells persist throughout life
After two decades in the United States, Martin Hetzer returned home to Austria in 2023 to become the 2nd President of the Institute of Science and Technology Austria (ISTA). A year into his new role, the molecular biologist remains engaged in the rea.....»»
Self-assembly of complex systems: Hexagonal building blocks are better
Complex systems in nature, like their synthetic counterparts in technology, comprise a large number of small components that assemble of their own accord through molecular interactions. Gaining a better understanding of the principles and mechanisms.....»»
Chinese scientists reveal the spinning mechanism of the silkworm
Mulberry silk is a natural protein fiber that is light, soft and fine in nature, known as the "second skin of the human body" and "Queen of fibers." China is the origin of the world's sericulture industry......»»
Study describes zinc oxide nanoparticle strategy for inactivation of multidrug-resistant bacteria
An article published in the Journal of Environmental Chemical Engineering describes a possible strategy for promoting selective inhibition of multidrug-resistant bacteria, which are increasingly abundant owing to the indiscriminate use of antibiotics.....»»
Molecular biology technique allows for discovery of novel targets for candidate vaccines against schistosomiasis
Researchers in Brazil have used an innovative technique in molecular biology to identify targets for candidate vaccines against Schistosoma mansoni, the parasite that causes schistosomiasis......»»
Researchers discover corn reduces arsenic toxicity in soil
When crops grow in arsenic-contaminated soil, this toxic element accumulates in the food chain. A study involving the University of Basel has now discovered a mechanism used by corn plants to reduce arsenic uptake: the key factor is a special substan.....»»
JWST observations explore molecular outflows of a nearby merging galaxy
Using the James Webb Space Telescope (JWST), an international team of astronomers has observed a nearby merging galaxy known as NGC 3256. Results of the observational campaign, presented March 21 on the pre-print server arXiv, yield essential informa.....»»
Researchers observe anomalously bright single-molecule upconversion electroluminescence phenomenon
A research group has developed a new and highly efficient upconversion luminescence mechanism by scanning tunneling microscopy (STM) induced luminescence to observe an extraordinarily bright single-molecule upconversion electroluminescence (UCEL) phe.....»»
New carbon nanotube transistor enhances sensitivity and resolution of molecule glasses
Researchers have developed a carbon nanotube (CNT) transistor for molecule glasses that facilitates detailed examination of molecular interactions. This innovative technology is poised to open a fresh research direction in nanotechnology and molecula.....»»
Researchers reveal structure and assembly mechanism of unique module in cellulosome
Cellulosomes are multi-enzyme complexes known for their efficient lignocellulose degradation, which is valuable in bioenergy technique development. The diverse composition and intricate assembly of cellulosomes give them exceptional substrate degrada.....»»
Gene editing technology reveals molecular mechanisms governing diatom population density signals
The intricate dynamics of diatom blooms, influenced by a myriad of external factors and internal signals, continue to fascinate scientists. After recognizing the potential role of density perception and intracellular signaling in dictating these phen.....»»
New hydrogel can stretch to 15 times its original size
A team of molecular engineers at Tsinghua University, in China, has developed a new type of hydrogel that can stretch to 15 times its original size and then snap back to its original form. In their study, published in the journal Science, the group m.....»»
Novel role for metabolites in cellular metabolism discovered
Investigators led by Issam Ben-Sahra, Ph.D., associate professor of Biochemistry and Molecular Genetics, have discovered how cellular metabolism fluctuates in response to changes in levels of pyrimidines, metabolites used by cells to make DNA and RNA.....»»
Researchers discover new microRNA-regulated pathway to boost iPS cell-derived platelet production
A team of researchers led by Professor Koji Eto (Department of Clinical Application) recently discovered the importance of a microRNA-based regulatory mechanism for enhancing the quality and quantity of platelets generated by iPS cell-derived megakar.....»»
Scientists discover a key quality-control mechanism in DNA replication
When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and is fraught with risks of mutation, which can lead to cell death or.....»»
Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment
Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. During this phase, a cell's D.....»»
If you"re getting dozens of password reset notifications, you"re being attacked
Apple users are becoming the target of a new wave of phishing attacks called "MFA Bombing" that relies on user impatience, and a bug in Apple's password reset mechanism.An example of the Apple ID password reset notificationPhishing attacks often rely.....»»
Team modulates electronic state of single-atom catalysts by CO molecular decoration for efficient methane conversion
Direct methane conversion has advantages such as low energy consumption, fewer processes, and better economics. However, it is difficult to activate methane at room temperature due to the high dissociation energy of C-H bonds of methane. Additionally.....»»