Molecular mechanism of ZDHHC18-mediated palmitoylation of cGAS in innate immunity inhibition
Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids......»»
Researchers demonstrate mechanism that may have stabilized the first RNA molecules
The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team at ORIGINS, a Munich-based Cluster of Excellence, has demonstrated a mechanism that could have.....»»
Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs
Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»
When it comes to DNA replication, humans and baker"s yeast are more alike than different, scientists discover
Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Scienc.....»»
Best OnePlus Open screen protectors to buy in 2024
Keep your OnePlus Open display safe and protected with these screen protectors. The post Best OnePlus Open screen protectors to buy in 2024 appeared first on Phandroid. The OnePlus Open is a foldable smartphone with a book-style mechanism......»»
Researchers decipher new molecular mechanisms related to biological tissue regeneration
A new study published in The EMBO Journal opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work......»»
Ice 0: Researchers discover a new mechanism for ice formation
Ice is far more complicated than most of us realize, with over 20 different varieties known to science, forming under various combinations of pressure and temperature. The kind we use to chill our drinks is known as ice I, and it's one of the few for.....»»
Spatially decoupling bromide-mediated process boosts propylene oxide electrosynthesis
A research team led by Prof. Zeng Jie and Geng Zhigang from the University of Science and Technology of China (USTC) of Chinese Academy of Sciences (CAS), utilized bromide as a reaction medium to spatially decouple the electrolysis process and propyl.....»»
New technique streamlines synthesis of heavy element compounds
Molecular compounds with heavy elements, like americium, curium and others can now be synthesized in a streamlined and efficient way thanks to a new technique developed by Lawrence Livermore National Laboratory (LLNL) researchers......»»
Sensing ultraviolet light with the help of molecular switches
The old saying "the dose makes the poison" also holds true for ultraviolet (UV) light. While UV light is essential for vitamin D production, it is also important in phototherapy, several industrial processes, and plant growth. It also has harmful eff.....»»
Discovery of Piezo1"s new signaling mechanism may aid search for better pain and itch treatments
The human body's sense of touch is so important it can be found throughout the body, not just on the skin. Two tiny sensors of touch, Piezo1 and Piezo2, signal the lightest pressures and can be found monitoring the circulatory system, telling the bod.....»»
Researchers zero in on the underlying mechanism that causes alloys to crack when exposed to hydrogen-rich environments
When deciding what material to use for infrastructure projects, metals are often selected for their durability. However, if placed in a hydrogen-rich environment, like water, metals can become brittle and fail. Since the mid-19th century, this phenom.....»»
Blue Origin shows off landing mechanism for New Glenn rocket
Blue Origin is aiming to land the first stage of its new rocket in late September, the New Glenn......»»
Scientists uncover the molecular mechanism behind pineapple peel coloration
Pineapple peel coloration, especially the red hue, significantly enhances its commercial and aesthetic value. However, the genetic mechanisms driving this trait are not well understood, complicating breeding efforts for red-skinned varieties......»»
Material with molecular trapdoor holds promise for highly selective gas adsorption
An international team led by scientists at City University of Hong Kong has found a flexible metal-organic framework (MOF) with one-dimensional channels that acts as a "molecular trapdoor" to selectively adsorb gases, such as carbon dioxide, in respo.....»»
Researchers identify structural characteristics of newly emerged SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to adapt to the herd immunity background and evolve into numerous sub-variants......»»
Scientists develop dual-functional, high-efficiency antimicrobial nanozyme
A research team led by Prof. Gao Lizeng from the Institute of Biophysics of the Chinese Academy of Sciences proposed a bactericidal mechanism based on nanozymes that simulate antimicrobial peptides (AMPs) and antimicrobial enzymes (AMEs) according to.....»»
E. coli variant may cause antimicrobial resistance in dogs, humans
Researchers studying antimicrobial-resistant E. coli—the leading cause of human death due to antimicrobial resistance worldwide—have identified a mechanism in dogs that may render multiple antibiotic classes ineffective......»»
Nano-confinement may be key to improving hydrogen production
Researchers at Lawrence Livermore National Laboratory (LLNL) have discovered a new mechanism that can boost the efficiency of hydrogen production through water splitting......»»
Interdisciplinary approach provides new insights into molecular mechanisms of cholera infection
Cholera infections caused by Vibrio cholerae bacteria can be life-threatening and the trigger is the cholera toxin produced by the bacteria. It binds to the surface of intestinal cells—more precisely, to certain "sugar lipids" (GM1 gangliosides, GM.....»»
Research team develops light-activated compounds to treat neuropathic pain
Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such as azobenzene. This allows th.....»»