Molecular link traced from gene to late-onset retinal degeneration
Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease. Researchers generated a 'disease-in-a-dish' model to study the disease.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
A record of the Earth’s temperature covering half a billion years
With one exception, a strong link between carbon dioxide and global temperatures. Enlarge / The cycle of building and breaking up of supercontinents seems to drive long-term climate trends. (credit: Walter Myers/Stocktrek Images).....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Team develops gene editing strategy for macroalgae Neopyropia
Neopyropia is an important economic macroalga and is one of the main macroalgae cultivation species in China, Japan, South Korea and other countries. As a critical juncture in the evolution of photosynthetic organisms, red algae to which Neopyropia b.....»»
New study takes the Earth’s temperature over a half-billion years
With one exception, a strong link between carbon dioxide and global temperatures. Enlarge / The cycle of building and breaking up of supercontinents seems to drive long-term climate trends. (credit: Walter Myers/Stocktrek Images).....»»
Researchers achieve aluminum molecular ring-based rotaxane and polyrotaxane
Rotaxanes have garnered interest for their unique structures consisting of mechanically interlocked axles and macrocycles. Numerous organic macrocycles have been employed to construct rotaxanes, including crown ether, cyclobis(paraquat-p-phenylene),.....»»
Genetic tracing at the Huanan Seafood market further supports COVID animal origins
A new international collaborative study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of meta.....»»
Researchers explore physiological and molecular processes underlying graft healing
Grafting has long been a cornerstone in agriculture and forestry, allowing for the propagation of desirable plant traits and improved resistance to environmental challenges. Despite its widespread application, grafting still encounters obstacles, inc.....»»
Gene-based model predicts when Japan"s cherry buds awake from dormancy
Japan in spring is famous for its cherry blossoms, or sakura, which begin flowering in the southern region of Kyushu and blaze upwards to the remote north of Hokkaido. The most abundant cherry tree cultivar, Somei Yoshino, is the iconic symbol of spr.....»»
New research reveals how "home" affects psychological well-being in a mobile world
A new study by Zahra Sharifonnasabi, Senior Lecturer in Marketing and Co-Director of the MINDS Research Group at Queen Mary University of London, sheds light on the link between "home" and psychological well-being for people who frequently move acros.....»»
Antioxidant carbon dot nanozymes alleviate depression in rats by restoring the gut microbiome
Depression is a significant challenge to diagnose and treat. Among the factors influencing depression onset and severity, there is growing evidence for chemical imbalances that generate oxidative stress throughout the body. To address this problem, r.....»»
Bioengineers create new substrate to study wood-decomposing enzyme
Researchers want to transform the natural and abundant resource wood into useful materials, and central to that is a molecular machine found in fungi that decomposes the complex raw material into its basic components......»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
DNA origami and fluorescent probes can precisely release molecular cargo
In the world of nanotechnology, the development of dynamic systems that respond to molecular signals is becoming increasingly important. The DNA origami technique, whereby DNA is programmed so as to produce functional nanostructures, plays a key role.....»»
Scientists find new epigenetic switch, revealing how genes are regulated in early development
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early emb.....»»
A Huge Tsunami Caused by a Thinning Glacier Created a Seismic Event for Nine Days
Scientists have traced a baffling monotonous planetary hum that lasted for nine days back to a glacier in Greenland.....»»
Q&A: Authors discuss addressing the crisis of species loss
No oncologist would wait for a patient's cancer to spread before treating it. Similarly, waiting to detect the potential loss of a species across all its known habitats means interventions are often too late to turn the tide of extinction, according.....»»
This wire-free TP-Link security camera is $70 today — you save $50
The TP-Link Tapo MagCam C425 security camera is on sale from Amazon with a $50 discount, and you can also get it as a bundle with a solar panel at $70 off......»»