Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment
Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. During this phase, a cell's D.....»»
Researchers study the intricacies of homologous recombination and abnormal chromosome bridges
Keeping the genetic information stored in genomic DNA intact during the cell division cycle is crucial for almost all lifeforms. Extensive DNA damage invariably causes various adverse genomic rearrangements, which can lead to cell death in the best c.....»»
Researchers reveal how molecular roadblocks slow the breakdown of cellulose for biofuels
Cellulose, which helps give plant cell walls their rigid structure, holds promise as a renewable raw material for biofuels—if researchers can accelerate the production process. Compared to the breakdown of other biofuel materials like corn, breakin.....»»
Study reveals differences in DNA folding between neurons and other brain cells, links them to cell functions
Researchers from Skoltech and their colleagues have investigated nerve cell regulation. Mounting knowledge of regulation mechanisms could enable a better understanding of how the healthy brain operates and what goes wrong in developmental and oncolog.....»»
Study sheds light on cancer cell "tug-of-war"
Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is a.....»»
How a "conductor" makes sense of chaos in early mouse embryos
Early embryonic development is tumultuous. It involves a rapid sequence of events, including cell division, differentiation, and lots of compartments moving around within each cell. Like an orchestra performance where each member of the band must sta.....»»
Laboratory and natural strains of intestinal bacterium turn out to have similar mutational profiles
Understanding mutational processes in a cell offers clues to the evolution of a genome. Most actively, mutation processes are studied in human cancer cells, while other genomes are often neglected......»»
Rich molecular language guides tiny liquid droplet formation in cells
Peering into a biological cell reveals a bustling microscopic world. The workhorses within this realm are specialized structures called organelles that perform vital cellular functions. Curiously, some organelles defy accepted convention: Instead of.....»»
Dogma-challenging telomere findings may offer new insights for cancer treatments
A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can.....»»
Geologists, biologists unearth the atomic fingerprints of cancer
Scientists at the University of Colorado Boulder and Princeton University have, for the first time, employed a tool often used in geology to detect the atomic fingerprints of cancer......»»
Researchers develop a nanoparticle that can penetrate the blood-brain barrier
Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier. Their goal is to kill primary breast cancer tumors and brain metastase.....»»
Attosecond core-level spectroscopy reveals real-time molecular dynamics
Chemical reactions are complex mechanisms. Many different dynamic processes are involved, affecting both the electrons and the nucleus of the present atoms. Very often, the strongly coupled electron and nuclear dynamics induce radiation-less relaxati.....»»
Simulated chemistry: New AI platform designs tomorrow"s cancer drugs
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen t.....»»
Researchers develop new AI tool for fast and precise tissue analysis to support drug discovery and diagnostics
A team of scientists from A*STAR's Genome Institute of Singapore (GIS) and Bioinformatics Institute (BII) has developed a new AI software tool called "BANKSY" that automatically recognizes the cell types present in a tissue, such as muscle cells, ner.....»»
First steps toward a whole-body map of molecular responses to exercise
Research definitively confirms that muscle-moving, calorie-burning activity slows the advance of disease, improves cognitive function, boosts the immune system, and reduces rates of mortality from all causes......»»
Functionalized chitosan as a biobased flocculant for the treatment of complex wastewater
Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have developed a biobased and functionalized flocculant to efficiently treat complex wastewaters. Furthermore, toxic phenols are removed from the water by the e.....»»
Male or female? Scientists discover the genetic mechanism that determines sex development in butterflies
Scientists of the Biology Centre, Czech Academy of Sciences, in collaboration with University of Liverpool have found the genetic mechanism that determines whether individuals of the butterfly species Bicyclus anynana become male or female......»»
Novel chemical tool for understanding membrane remodeling in the cell
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell......»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Siri for iOS 18 to gain massive AI upgrade via Apple"s Ajax LLM
Several of Apple's standard system components are on the verge of receiving significant AI-related enhancements, with Safari, Spotlight Search, and Siri being first in line for the treatment.Apple AI will make Siri, Safari, Spotlight, and Messages be.....»»
Researchers develop "founding document" on synthetic cell development
Cells are the fundamental units of life, forming the variety of all living things on Earth as individual cells and multicellular organisms. To better understand how cells perform the essential functions of life, scientists have begun developing synth.....»»