Martynoside found to rescue 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A
Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic stem cells, and its disrupt.....»»
Cellular clean energy: Can mitochondria make more energy without collateral damage?
Is it possible to amp up the energy production of mitochondria without also boosting potentially harmful byproducts? If so, such a method could be used to treat a host of neurodegenerative diseases in which impaired mitochondria are believed to play.....»»
New findings reveal koalas" health risks following bushfires, will aid in future rescue efforts
A new publication featured in Veterinary Sciences will guide future wildlife rescue and rehabilitation after Australian bushfires. These findings provide critical information for improving koala care during subsequent fire seasons......»»
The ViXion01 could be a useful wearable for people struggling to focus their eyes
A lot of us with non-impaired vision probably take for granted that we have relatively no issues with seeing things. However, there are many things that can affect eyesight. This includes medical issues or simply by getting older. For those who might.....»»
Snow hinders rescues and aid deliveries to isolated communities after Japan quakes kill 161 people
Rescue teams worked through snow to deliver supplies to isolated hamlets Monday, a week after a powerful earthquake hit western Japan, killing at least 161 people......»»
Scenes of loss play out across Japan"s western coastline after quake kills 92, dozens still missing
His face hidden under a humble straw hat, the man silently watched as several helmeted rescue workers carefully lifted from the rubble his wife's body, wrapped in blue plastic on a stretcher......»»
Procrastinators unite: Shop Best Buy"s Last-Minute Sales Event for same-day delivery or pickup
Best Buy's Last-Minute Sales Event features deals on brands like Apple, Xbox, KitchenAid, and Lego. Score same-day delivery or pickup through Dec. 24. Through Dec. 24, Best Buy comes to procrastinators' rescue with a Last-Minute Sales Event tha.....»»
VanMoof rescue plan will see replacement parts; new sales; e-scooter [U]
Anyone with a VanMoof ebike is likely concerned after the Dutch company confirmed that it is in financial trouble (and subsequently declared bankrupt). Update: The new owners have announced details of the rescue plan, set to roll out in the first.....»»
Scientists discover novel way to attack the trypanosome parasite through its ribosome
Trypanosome is a single-celled parasite that takes an extensive human and economic toll due to its involvement in causing sleeping sickness in humans and a similar disease in cattle. The parasite, found mainly in rural areas of Africa, is transmitted.....»»
Rescue teams evacuate flood-ravaged Australian town
Rescue teams on Tuesday evacuated a flood-ravaged town in northeastern Australia, racing to airlift hundreds of people to safety before they run out of food and water......»»
Satellite SOS is a game changer, says LA Search and Rescue
Search and rescue chiefs in the Los Angeles County Sheriff's Department (LASD) can't praise the iPhone's Emergency SOS via Satellite enough.Apple's Emergency SOS feature on iPhonesIt was Apple's Emergency SOS via Satellite feature that led an LASD te.....»»
Apple Watch fall detection helps hiker get help after after near-fatal fall
The Apple Watch’s fall detection feature came to the rescue for a man in Georgia, according to a new report from Fox5 Atlanta. Mike Menand was on a hike in the Chattahoochee River National Recreation Area earlier this year when his two dogs spotted.....»»
Climate economists identify interventions that could rescue 1.5°C Paris Agreement goal
To meet the goals of the Paris Agreement and limit global heating to 1.5°C, global annual emissions will need to drop radically over the coming decades. A new paper from climate economists at the University of Oxford says that this goal could still.....»»
National Transportation Safety Board wants anti-speeding tech in new cars
The NTSB issued the recommendation after determining a deadly crash in suburban Las Vegas was caused by excessive speeding, drug-impaired driving and Nevada's failure to hold the driver accountable despite numerous speeding citations......»»
"The Marvels" review: Ms. Marvel tries to rescue the MCU from itself
Iman Vellani. Brie Larson, and Teyonah Parris join forces in the MCU's latest adventure. Nia DaCosta directs. Movie review. 2023 has been a pretty miserable year for superhero movies, bringing us the underwhelming Shazam! Fury of the Gods, the.....»»
Fall COVID shot uptake is an “abysmal” 7%; wastewater testing impaired
Meanwhile, a quarter of the country's wastewater testing sites are offline. Enlarge (credit: Getty | Lindsey Nicholson) More than a month since US health officials recommended updated COVID-19 vaccines for all Americans.....»»
With salmon at risk of extinction, California begins urgent rescue effort
Typically, now is the time when creeks along the Sacramento River are filled with young spring-run Chinook salmon preparing to make their journey downstream to the Pacific Ocean, where they will mature, and eventually make their return to California.....»»
Leap in the dark: On a mission to rescue the Caribbean"s biggest frog
A rescue mission is under way in the Caribbean to save one of the world's largest—and rarest—frogs from extinction......»»
At least 10 dead, 102 missing in India glacial lake burst
Indian rescue teams searched on Thursday for 102 people missing after a devastating flash flood triggered by a high-altitude glacial lake burst killed at least 10, officials said......»»
Striking rare gold: Researchers unveil new material infused with gold in an exotic chemical state
For the first time, Stanford researchers have found a way to create and stabilize an extremely rare form of gold that has lost two negatively charged electrons, denoted Au2+. The material stabilizing this elusive version of the valued element is a ha.....»»
Tree-hugging AI to the rescue of Brazilian Amazon
Small, artificially intelligent boxes tied to tree trunks in the Brazilian Amazon are the latest weapon in the arsenal of scientists and environmentalists battling destructive jungle invaders......»»