Martynoside found to rescue 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A
Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic stem cells, and its disrupt.....»»
Mitochondrial ribosome assembly in 3D
In a study published in Nature Communications, researchers at Karolinska Institutet provide insight into the sequence of events leading to formation of functional mitoribosomes and sheds light on the mechanism of action of nine mitoribosome assembly.....»»
Sugar overload may be a recipe for long-term problems
Children who consume too much sugar could be at greater risk of becoming obese, hyperactive, and cognitively impaired, as adults, according to the results of a new study......»»
Study uses candy-like models to make STEM accessible to visually impaired students
About 36 million people have blindness including 1 million children. Additionally, 216 million people experience moderate to severe visual impairment. However, STEM (science, technology, engineering and math) education maintains a reliance on three-d.....»»
"Rescue mutations" that suppress harmful DNA changes could shed light on origins of genetic disorders
New insights into the ability of DNA to overcome harmful genetic changes have been discovered by scientists at the Wellcome Sanger Institute, the University of Lausanne and their collaborators. The team found that 26 percent of harmful mutations were.....»»
Suspected fatal shark attack in New Caledonia
Rescue services in New Caledonia were Thursday searching for the body of a fisherman believed to have been killed by a shark, following a spate of fatal attacks in the South Pacific territory this year......»»
Research shows two invasive beachgrasses are hybridizing
Two species of sand-stabilizing beachgrasses introduced to the Pacific Northwest starting in the early 1900s are hybridizing, raising new questions about impacts to the coastal ecosystems the non-native plants have been engineering for more than a ce.....»»
Mount Vesuvius victims died just moments away from rescue
A skeleton unearthed at the site may belong to a high-ranking naval officer. armi del soldato When Mount Vesuvius destroyed the Roman city of Pompeii in 79 CE, the eruption also killed hundreds of people huddled on the shores of nearby Hercul.....»»
Online therapy effective against OCD symptoms in the young
Obsessive-compulsive disorder (OCD) in children and adolescents is associated with impaired education and worse general health later in life. Access to specialist treatment is often limited. According to a new study, internet-delivered cognitive beha.....»»
16-bit classics Zombies Ate My Neighbors and Ghoul Patrol are getting modern re-releases
Zombies first arrived on the Super Nintendo in September 1993 before finding its way to the Sega Genesis a couple of months later. In it, players controlled protagonists Julie and Zeke as they attempted to rescue their neighbors from characters typic.....»»
Undetected early heart damage raises risk of death in hospitalized COVID-19 patients
First-phase ejection fraction, a possible indicator of heart failure, is a strong predictor of survival in hospitalized COVID-19 patients, according to a new study. Hospitalized patients who had impaired first-phase ejection fraction were nearly 5 ti.....»»
"I was injured but the rescue boat found me in seconds"
How technology has helped emergency responders save lives during the pandemic......»»
Kids with a desk and a quiet place to study do better in school, data shows
Ask what students need to learn at home, and the answer often involves access to Wi-Fi or a digital device. For example, the American Rescue Plan Act of 2021 sets aside US$7.1 billion to support access to high-speed internet for schools and libraries.....»»
Lost in the Med: Pacific grey whale ventures far from home
A young grey whale has been sighted off the southern French coast in recent days, lost in the Mediterranean and trying unsuccessfully to make it back to its natural habitat—the northern Pacific—the national network for the rescue of sea mammals s.....»»
Asbury rebounds in Q1 from coronavirus-impaired quarter in 2020
Asbury's core business lines improved in double-digit percentages across the board compared with the coronavirus-impacted quarter last year. The company's omnichannel tool Clicklane also rolled out to all of its dealerships......»»
Ocean debris again in spotlight as entangled baby whale struggles off California
The plight of an entangled baby whale off Orange County, California, has sparked an urgent multi-agency rescue effort, highlighting again the perils that ocean debris poses to marine mammals and other wildlife......»»
Researchers rescue endangered black abalone buried by debris flows
The Big Sur coast is prime habitat for black abalone and has had one of the few remaining healthy populations of this endangered species. So when heavy winter rains triggered debris flows from the Dolan Fire burn scar, dumping tons of sediment onto t.....»»
Rescue hampered by distance as more rain falls in Indonesia
Rescuers were hampered by damaged bridges and roads and a lack of heavy equipment Monday after torrential rains caused multiple disasters on remote eastern Indonesian islands......»»
About 4,300 cold-stunned turtles survived the Texas freeze
About a third of the cold-stunned sea turtles found along Texas' coast during last month's deadly winter freeze survived following a massive rescue effort by experts and volunteers who were themselves struggling without power at home......»»
Australia"s "Big Wet" eases, but thousands still isolated
Rescue teams raced emergency supplies to flood-hit Australians Wednesday, as trapped residents waited for still-swollen rivers to ebb, so the long, hard clean-up can begin......»»
New technologies, new responsibilities: Ethical risk assessment for northern white rhino rescue program
The BioRescue consortium develops and applies new technological approaches as a last straw for saving critically endangered species such as the northern white rhinoceros. advanced assisted reproductive technologies (aART) push the boundaries of what.....»»