Lipid epoxides target pain, inflammatory pathways in neurons
When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report. T.....»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
Indigenous US farm workers face greater job-related pain compared to undocumented peers, study suggests
Farming is a notoriously hard profession with long hours spent operating dangerous equipment and performing other arduous tasks. New Rice University research finds that Indigenous farm employees—many of whom have legal status in the U.S. after movi.....»»
SCCMSecrets: Open-source SCCM policies exploitation tool
SCCMSecrets is an open-source tool that exploits SCCM policies, offering more than just NAA credential extraction. SCCM policies are a key target for attackers in Active Directory environments, as they can expose sensitive technical information, incl.....»»
Study: Cats in little crocheted hats shed light on feline chronic pain
The custom-made caps hold electrodes in place and reduce motion artifacts during EEGs. Enlarge / “When you spend more time putting electrodes back on than you do actually recording the EEGs, you get creative." (credit: Alienor.....»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Researchers uncover key insights into cholesterol"s structure in cell membranes
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. Th.....»»
Proof-of-concept study uses X-rays to target mock-up asteroids in a vacuum
An X-ray pulse may be able to vaporize the surface of an asteroid and change its trajectory, according to a proof-of-concept paper published in Nature Physics. A laboratory experiment that mimics the deflection of an asteroid model using this techniq.....»»
Elon Musk shares new target date for Starship voyage to Mars
But it's worth noting that the SpaceX CEO's forecasts often slip......»»
Evidence tells us voters might be convinced to accept short-term pain for long-term gain—but it will be a hard sell
In the build-up to his government's first budget, Prime Minister Keir Starmer has been setting expectations low. It will be "painful," he has warned, and a "difficult trade-off" will have to be made because of the economic inheritance left by the las.....»»
Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?
Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?.....»»
How much auto demand will the Fed"s half-point rate cut produce?
The Federal Reserve cut its benchmark rate target 0.5 percentage points on Sept. 18, which could reduce the market interest rates that Cox Automotive polling indicates are dealerships' No. 1 challenge......»»
Copper-based nanocapsules shown to enhance radiotherapy effectiveness
In a study published in Nature Nanotechnology, researchers discovered that cuproptosis may serve as a new target for radiosensitization in re-irradiation......»»
Exploring the interplay between phosphate signaling and jasmonate pathways in tea plants
Catechins, the key active components in tea, are known for their protective effects against conditions like diabetes, cancer, and cardiovascular diseases. However, their biosynthesis is highly sensitive to environmental factors, particularly phosphat.....»»
This Whirlpool mini fridge is only $110 today at Target — normally it’s $150
Want a place to store cold drinks and snacks? This Whirlpool mini fridge deal at Target is just what you need to shop. Check it out......»»
Strange Visual Auras Could Hold the Key to Better Migraine Treatments
Research on the visual patterns that foreshadow migraines may reveal clues on how painful headaches arise from the brain even though it has no pain receptors......»»
Decoding "Chachi" citrus: Unveiling the secrets of flavorful phytonutrients
Citrus reticulata "Chachi" (CRC), a staple in traditional medicine and modern pharmacology, is renowned for its rich flavonoid content, which underpins its health-promoting properties. Despite its widespread use, the biosynthetic pathways and genetic.....»»
8-year-old who drove to an Ohio Target in mom"s SUV caught on dashcam video: Watch
8-year-old who drove to an Ohio Target in mom"s SUV caught on dashcam video: Watch.....»»
Half-point Fed rate cut could spur consumer demand at auto dealerships
Car dealerships might see higher demand from consumers following the Federal Reserve's decision Sept. 18 to cut its benchmark rate target 0.5 points, according to Edmunds......»»
Southern California suspects burglarize Target, hide stolen goods in baby stroller
Southern California suspects burglarize Target, hide stolen goods in baby stroller.....»»