Iridium-catalyzed Z-retentive asymmetric allylic substitution reactions
In synthetic organic chemistry, Z-olefins are a challenging synthetic target to produce in the lab due to their relative thermodynamic instability. The Z-olefins form an unsaturated compound with a CnH2n formula that can be readily isomerized. Analog.....»»
Video: What is life? And will we find it on other planets?
Chemistry is helping us figure out how life got started on Earth and is giving us molecules to look for on other planets. In this episode of Reactions, we break down what "life" is and how likely we are to find it out in the cosmos:.....»»
Covering metal catalyst surfaces with thin two-dimensional oxide materials can enhance chemical reactions
Physically confined spaces can make for more efficient chemical reactions, according to recent studies led by scientists from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory. They found that partially covering metal surfaces acti.....»»
Electrophotocatalytic diamination of vicinal C–H bonds
In organic chemistry, the conversion of inactivated carbon-hydrogen (C-H) bonds to carbon-nitrogen (C-N) bonds is a highly valued transformation. Scientists can accomplish such reactions at only a single C-H site since the first derivatization can di.....»»
Ultrafast electron dynamics in space and time
Often depicted as colorful balloons or clouds, electron orbitals provide information on the whereabouts of electrons in molecules, a bit like fuzzy snapshots. In order to understand the exchange of electrons in chemical reactions, it is not only impo.....»»
Giving oxygen to the question of air quality
The simplest of organic molecules have a much more complex relationship with oxygen than previously thought. Researchers from KAUST and their international collaborators have shown that alkanes participate extensively in autoxidation reactions with o.....»»
Breakthrough in organic chemistry: Asymmetric syntheses of useful, unique chiral compounds
Atropisomers are a class of stereoisomers (chemical compounds that differ in spatial arrangement of atoms) arising from restricted rotation around a single bond and have various applications in chemistry. To date, most research on atropisomers has fo.....»»
How can researchers quickly access complex molecules for drug discovery?
The function of molecules used in drugs in part depends on their structure, including the many chemical bonds between their atoms. These molecules can be built through several different chemical reactions, most of which are slow and inefficient becau.....»»
Iridium-catalyzed Z-retentive asymmetric allylic substitution reactions
In synthetic organic chemistry, Z-olefins are a challenging synthetic target to produce in the lab due to their relative thermodynamic instability. The Z-olefins form an unsaturated compound with a CnH2n formula that can be readily isomerized. Analog.....»»
Bond-selective reactions observed during molecular collisions
A team of researchers from Germany and the U.K. has found that bond-selective reactions can be observed during certain molecular collisions. In their paper published in the journal Physical Review Letters, the group describes experiments they conduct.....»»
1918 pandemic second wave had fatal consequences
In a pandemic, delayed reactions and a decentralized approach by the authorities at the start of a follow-up wave can lead to longer-lasting, more severe and more fatal consequences, a new study has found. Researchers compared the influenza pandemic.....»»
New method for asymmetric N,N-acetal synthesis promises advances in drug development
Chiral N,N-acetals are an important component of several bioactive drugs and medicines. Owing to this, chemical reactions that lead to high-purity yield of the desired 'enantiomeric' form are highly sought after. In a new study, scientists demonstrat.....»»
New method for asymmetric N,N-acetal synthesis promises advances in drug development
A lot of our medicines and other bioactive drugs are based on chemical structures called enantiomers—molecules that are mirror images of each other and are non-superimposable. Notable among them are chiral N,N-acetals contained in diuretic drugs li.....»»
Understanding catalytic couplings: not all synergies are simple
Negishi cross-coupling reactions have been widely used to form C-C bonds since the 1970s and are often perceived as the result of two metals, zinc and palladium/nickel, working in synergy. But like all relationships, there is more under the surface......»»
Mysterious organic scum boosts chemical reaction efficiency, may reduce chemical waste
Chemical manufacturers frequently use toxic solvents such as alcohols and benzene to make products like pharmaceuticals and plastics. Researchers are examining a previously overlooked and misunderstood phenomenon in the chemical reactions used to mak.....»»
Scientists find a way to accelerate DNA surface hybridization
Scientists globally aim to control chemical reactions—an ambitious goal that requires identifying the steps taken by initial reactants to arrive at the final products as the reaction takes place. While this dream remains to be realized, techniques.....»»
Measuring ozone chemistry in an occupied residence
An international team of researchers has taken a look at the amount of ozone in an occupied residence in order to measure both ozone and volatile organic compounds (VOCs) associated with chemical reactions with ozone. In their paper published in Proc.....»»
Facebook-style reactions are coming to Outlook
Microsoft’s product roadmap shows a feature in development called “Outlook for the web: React to an email message.” It describes users being able to react to an email without sending one of their own through a range of reactions......»»
Well connected through amides
Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. In the journal Angewandte Chemie, scientists have now introduced a new type of reaction for making amide bonds. Called an A.....»»
Future options for storing carbon dioxide: Synthesis of inorganic heteroalkenes
Group 13/15 heteroalkenes RMER' with M-E double bonds (M = B-Tl; E = N-Bi) offer promising potential for bond activation reactions, but they are difficult to prepare. A team led by CENIDE professor Stephan Schulz now describes new synthetic methods f.....»»
Pillar-like molecules as biosensors for metabolites
Metabolites are organic molecules that take part in or are created during the biochemical reactions constantly taking place in an organism. For the human body, more than 110,000 metabolites have been identified. Metabolites play a role in metabolic s.....»»